PDB: 202 resultsInfo pagesStatus searchChemie searchBIRD

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5A50	The crystal structure of Arabidopsis thaliana CAR4 in complex with two calcium ions, Zn and Phopho Choline Descriptor: AT3G17980, CALCIUM ION, PHOSPHOCHOLINE, ... Authors: Diaz, M, Albert, A. Deposit date: 2015-06-16 Release date: 2016-03-02 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Calcium-Dependent Oligomerization of Car Proteins at Cell Membrane Modulates Aba Signaling. Proc.Natl.Acad.Sci.USA, 113, 2016
5A51	The crystal structure of Arabidopsis thaliana CAR4 in complex with two calcium ions and phophatidyl serine Descriptor: AT3G17980, CALCIUM ION, PHOSPHOSERINE Authors: Diaz, M, Albert, A. Deposit date: 2015-06-16 Release date: 2016-03-02 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.602 Å) Cite: Calcium-Dependent Oligomerization of Car Proteins at Cell Membrane Modulates Aba Signaling. Proc.Natl.Acad.Sci.USA, 113, 2016
2YOA	Synaptotagmin-1 C2B domain with phosphoserine Descriptor: CALCIUM ION, PHOSPHOSERINE, SYNAPTOTAGMIN-1, ... Authors: Honigmann, A, van den Bogaart, G, Iraheta, E, Risselada, H.J, Milovanovic, D, Mueller, V, Muellar, S, Diederichsen, U, Fasshauer, D, Grubmuller, H, Hell, S.W, Eggeling, C, Kuhnel, K, Jahn, R. Deposit date: 2012-10-22 Release date: 2013-03-20 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Phosphatidylinositol 4,5-Bisphosphate Clusters Act as Molecular Beacons for Vesicle Recruitment Nat.Struct.Mol.Biol., 20, 2013
6CXW	Synaptotagmin 1 C2A beta4 chimera with enhanced PIP2 binding function Descriptor: Synaptotagmin 1 C2A beta4 chimera Authors: Sutton, R.B. Deposit date: 2018-04-04 Release date: 2019-04-17 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.832 Å) Cite: Engineering a C2-domain to bind PIP2 To Be Published
6TZ3	Crystal Structure of Human Synaptotagmin 1 C2B without Ca2+ Descriptor: SULFATE ION, Synaptotagmin-1 Authors: Dominguez, M.J, Karmakar, S, Meyer, A.G, Sutton, R.B. Deposit date: 2019-08-09 Release date: 2020-05-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.17 Å) Cite: Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. Neuron, 107, 2020
6U41	1.7 angstrom structure of a pathogenic human Syt 1 C2B (D304G) Descriptor: SULFATE ION, Synaptotagmin-1 Authors: Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B. Deposit date: 2019-08-22 Release date: 2020-05-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. Neuron, 107, 2020
6U4U	1.3 A structure of a pathogenic human Syt 1 C2B (I368T) Descriptor: SULFATE ION, Synaptotagmin-1 Authors: Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B. Deposit date: 2019-08-26 Release date: 2020-05-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. Neuron, 107, 2020
4IQH	Crystal Structure Analysis of Dysferlin C2A variant 1 (C2Av1) Descriptor: Dysferlin Authors: Sutton, R.B, Fuson, K.L. Deposit date: 2013-01-11 Release date: 2013-12-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.764 Å) Cite: Alternate Splicing of Dysferlin C2A Confers Ca(2+)-Dependent and Ca(2+)-Independent Binding for Membrane Repair. Structure, 22, 2014
4RJ9	Structure of a plant specific C2 domain protein, OsGAP1 from rice Descriptor: C2 domain-containing protein-like, POTASSIUM ION Authors: Miao, R, Fong, Y.H, Wong, K.B, Lam, H.M. Deposit date: 2014-10-08 Release date: 2015-08-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1). J.Biol.Chem., 290, 2015
6U4W	1.4 A structure of a pathogenic human Syt 1 C2B (D366E) Descriptor: SULFATE ION, Synaptotagmin-1 Authors: Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B. Deposit date: 2019-08-26 Release date: 2020-05-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. Neuron, 107, 2020
8FAF	Unedited Octopus bimaculoides Synaptotagmin 1 C2A at room temperature Descriptor: Synaptotagmin Authors: McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.C, Sutton, R.B. Deposit date: 2022-11-26 Release date: 2023-07-19 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Temperature-dependent RNA editing in octopus extensively recodes the neural proteome. Cell, 186, 2023
8FAM	Edited Octopus bimaculoides Synaptotagmin 1 C2A (I248V) at room temperature Descriptor: Synaptotagmin Authors: McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.J, Sutton, R.B. Deposit date: 2022-11-28 Release date: 2023-07-19 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Temperature-dependent RNA editing in octopus extensively recodes the neural proteome. Cell, 186, 2023
4TS6	Crystal structure of the RIM C2A domain from Drosophila. Descriptor: GLYCEROL, Rab3 interacting molecule variant 2 Authors: Hatzopoulos, G.N, Shiroma, J, Vakonakis, I. Deposit date: 2014-06-18 Release date: 2015-07-01 Last modified: 2024-08-07 Method: X-RAY DIFFRACTION (1.92 Å) Cite: The human cognition-enhancing CORD7 mutation increases active zone number and synaptic release. Brain, 145, 2022
6BTY	Crystal structure of the PI3KC2alpha C2 domain in space group P41212 Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Authors: Chen, K.-E, Collins, B.M. Deposit date: 2017-12-08 Release date: 2018-10-17 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.678 Å) Cite: Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26, 2018
6EEL	Crystal Structure of Myoferlin C2A with divalent cation Descriptor: Myoferlin, STRONTIUM ION Authors: Sutton, R.B, Harsini, F.M, Rice, A.M. Deposit date: 2018-08-14 Release date: 2019-05-22 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Structural Basis for the Distinct Membrane Binding Activity of the Homologous C2A Domains of Myoferlin and Dysferlin. J.Mol.Biol., 431, 2019
6BTZ	Crystal structure of the PI3KC2alpha C2 domain in space group C121 Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, GLYCEROL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, ... Authors: Chen, K.-E, Collins, B.M. Deposit date: 2017-12-08 Release date: 2018-10-17 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26, 2018
6BU0	Crystal structure of the PI3KC2alpha C2 domain in complex with IP6 Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, FORMIC ACID, INOSITOL HEXAKISPHOSPHATE, ... Authors: Chen, K.-E, Collins, B.M. Deposit date: 2017-12-08 Release date: 2018-10-17 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.427 Å) Cite: Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26, 2018
4ICX	N-terminal C2 domain of human CEP120 Descriptor: Centrosomal protein of 120 kDa Authors: Janowski, R, Guarin, N, Coll, M. Deposit date: 2012-12-11 Release date: 2014-06-18 Method: X-RAY DIFFRACTION (2.7 Å) Cite: N-terminal C2 domain tandem of human CEP120 shows lipid binding properties To be Published
4ICW	N-terminal C2 domain of human CEP120 Descriptor: Centrosomal protein of 120 kDa Authors: Janowski, R, Guarin, N, Coll, M. Deposit date: 2012-12-11 Release date: 2014-06-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.2 Å) Cite: N-terminal C2 domain tandem of human CEP120 shows lipid binding properties To be Published
4IHB	X-RAY STRUCTURE OF THE canonical C2A DOMAIN FROM HUMAN DYSFERLIN Descriptor: CALCIUM ION, Dysferlin, FORMIC ACID Authors: Sutton, R.B, Fuson, K.L. Deposit date: 2012-12-18 Release date: 2013-12-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.044 Å) Cite: Alternate Splicing of Dysferlin C2A Confers Ca(2+)-Dependent and Ca(2+)-Independent Binding for Membrane Repair. Structure, 22, 2014
4L1L	Rat PKC C2 domain bound to CD Descriptor: CADMIUM ION, Protein kinase C alpha type, SULFATE ION Authors: Morales, K.M, Yang, Y, Long, Z, Li, P, Taylor, A.B, Hart, P.J, Igumenova, T.I. Deposit date: 2013-06-03 Release date: 2013-08-28 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Cd(2+) as a ca(2+) surrogate in protein-membrane interactions: isostructural but not isofunctional. J.Am.Chem.Soc., 135, 2013
6FB4	human KIBRA C2 domain mutant C771A Descriptor: GLYCEROL, PHOSPHATE ION, Protein KIBRA Authors: Crennell, S.J, Posner, M.G, Bagby, S. Deposit date: 2017-12-18 Release date: 2018-05-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.415631 Å) Cite: Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain. J. Biol. Chem., 293, 2018
6FJC	Human KIBRA C2 domain mutant C771A in complex with phosphatidylinositol 3,4,5-trisphosphate Descriptor: (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, GLYCEROL, Protein KIBRA, ... Authors: Crennell, S.J, Posner, M.G, Bagby, S. Deposit date: 2018-01-22 Release date: 2018-05-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.598 Å) Cite: Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain. J. Biol. Chem., 293, 2018
6FJD	Human KIBRA C2 domain mutant C771A in complex with phosphatidylinositol 4,5-bisphosphate Descriptor: (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE, GLYCEROL, Protein KIBRA, ... Authors: Crennell, S.J, Posner, M.G, Bagby, S. Deposit date: 2018-01-22 Release date: 2018-05-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.898 Å) Cite: Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain. J. Biol. Chem., 293, 2018
6FD0	Human KIBRA C2 domain mutant M734I S735A Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Protein KIBRA Authors: Crennell, S.J, Posner, M.G, Bagby, S. Deposit date: 2017-12-21 Release date: 2018-05-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.64215851 Å) Cite: Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain. J. Biol. Chem., 293, 2018

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