6U4U
1.3 A structure of a pathogenic human Syt 1 C2B (I368T)
Summary for 6U4U
Entry DOI | 10.2210/pdb6u4u/pdb |
Related | 1UOW |
Descriptor | Synaptotagmin-1, SULFATE ION (3 entities in total) |
Functional Keywords | c2 domain, c2b, greek key, exocytosis |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 18732.33 |
Authors | Dominguez, M.J.,Bradberry, M.M.,Chapman, E.R.,Sutton, R.B. (deposition date: 2019-08-26, release date: 2020-05-13, Last modification date: 2023-10-11) |
Primary citation | Bradberry, M.M.,Courtney, N.A.,Dominguez, M.J.,Lofquist, S.M.,Knox, A.T.,Sutton, R.B.,Chapman, E.R. Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. Neuron, 107:52-64.e7, 2020 Cited by PubMed: 32362337DOI: 10.1016/j.neuron.2020.04.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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