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6U4U

1.3 A structure of a pathogenic human Syt 1 C2B (I368T)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Synaptotagmin-1polymer15717867.81UniProt (P21579)
Pfam (PF00168)
Homo sapiens (Human)Synaptotagmin I,SytI,p65
2B, C, D, E, F...
(A)
SULFATE IONnon-polymer96.19Chemie (SO4)
3K
(A)
waterwater18.0217Chemie (HOH)
Sequence modifications
A: 272 - 422 (UniProt: P21579)
PDBExternal DatabaseDetails
Gly 266-expression tag
Asp 267-expression tag
Ile 268-expression tag
Thr 269-expression tag
His 270-expression tag
Met 271-expression tag
Thr 368Ile 368engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight17867.8
Non-Polymers*Number of molecules9
Total formula weight864.6
All*Total formula weight18732.3
*Water molecules are not included.

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PDB entries from 2026-01-21

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