6U4W
1.4 A structure of a pathogenic human Syt 1 C2B (D366E)
Summary for 6U4W
| Entry DOI | 10.2210/pdb6u4w/pdb |
| Related | 1UOW |
| Descriptor | Synaptotagmin-1, SULFATE ION (3 entities in total) |
| Functional Keywords | c2 domain, c2b, greek key, baker-gordon syndrome, exocytosis |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 18278.10 |
| Authors | Dominguez, M.J.,Bradberry, M.M.,Chapman, E.R.,Sutton, R.B. (deposition date: 2019-08-26, release date: 2020-05-13, Last modification date: 2023-10-11) |
| Primary citation | Bradberry, M.M.,Courtney, N.A.,Dominguez, M.J.,Lofquist, S.M.,Knox, A.T.,Sutton, R.B.,Chapman, E.R. Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder. Neuron, 107:52-64.e7, 2020 Cited by PubMed: 32362337DOI: 10.1016/j.neuron.2020.04.003 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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