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9ILB	HUMAN INTERLEUKIN-1 BETA Descriptor: PROTEIN (HUMAN INTERLEUKIN-1 BETA) Authors: Yu, B, Blaber, M, Gronenborn, A.M, Clore, G.M, Caspar, D.L.D. Deposit date: 1998-10-22 Release date: 1999-01-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Disordered water within a hydrophobic protein cavity visualized by x-ray crystallography. Proc.Natl.Acad.Sci.USA, 96, 1999
41BI	INTERLEUKIN-1 BETA (IL-1 BETA) (MUTANT WITH CYS 8 REPLACED BY ALA (C8A) Descriptor: INTERLEUKIN-1 BETA Authors: Veerapandian, B, Poulos, T.L, Gilliland, G.L, Masui, Y, Hirai, Y. Deposit date: 1992-02-03 Release date: 1992-04-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9 Å) Cite:
7CHY	Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26 Descriptor: Interleukin-1 beta, heavy chain of antibody binding fragment of IgG26, light chain of antibody binding fragment of IgG26 Authors: Lee, C.C, Wang, A.H.J, Kuo, W.C. Deposit date: 2020-07-06 Release date: 2021-01-13 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structure-based Development of Human Interleukin-1 beta-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP. J.Mol.Biol., 433, 2020
7CHZ	Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26A Descriptor: Interleukin-1 beta, heavy chain of antibody binding fragment of IgG26A, light chain of antibody binding fragment of IgG26A Authors: Lee, C.C, Wang, A.H.J, Kuo, W.C. Deposit date: 2020-07-06 Release date: 2021-01-13 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure-based Development of Human Interleukin-1 beta-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP. J.Mol.Biol., 433, 2020
4P0L	Crystal Structure of Double Loop-Swapped Interleukin-36Ra With Additional Point Mutations Descriptor: Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein Authors: Guenther, S, Sundberg, E.J. Deposit date: 2014-02-21 Release date: 2014-06-25 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor. J Immunol., 193, 2014
4P0K	Crystal Structure of Double Loop-Swapped Interleukin-36Ra Descriptor: Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein Authors: Guenther, S, Sundberg, E.J. Deposit date: 2014-02-21 Release date: 2014-06-25 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor. J Immunol., 193, 2014
4P0J	Crystal Structure of Loop-Swapped Interleukin-36Ra Descriptor: Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein Authors: Guenther, S, Sundberg, E.J. Deposit date: 2014-02-21 Release date: 2014-06-25 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.298 Å) Cite: Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor. J Immunol., 193, 2014
4EEE	Crystal Structure of YLDV 14L IL-18 Binding Protein in Complex with Human IL-18 Descriptor: 14L protein, Interleukin-18 Authors: Krumm, B.E, Xiang, Y, Deng, J. Deposit date: 2012-03-28 Release date: 2012-09-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.71 Å) Cite: A unique bivalent binding and inhibition mechanism by the yatapoxvirus interleukin 18 binding protein. Plos Pathog., 8, 2012
3WO2	Crystal structure of human interleukin-18 Descriptor: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Interleukin-18, SULFATE ION Authors: Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H. Deposit date: 2013-12-19 Release date: 2014-12-17 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.33 Å) Cite: The structural basis for receptor recognition of human interleukin-18 Nat Commun, 5, 2014
3WO3	Crystal structure of IL-18 in complex with IL-18 receptor alpha Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H. Deposit date: 2013-12-19 Release date: 2014-12-17 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.1 Å) Cite: The structural basis for receptor recognition of human interleukin-18 Nat Commun, 5, 2014
3LTQ	Structure of Interleukin 1B solved by SAD using an inserted Lanthanide Binding Tag Descriptor: ACETATE ION, Interleukin-1 beta, SULFATE ION, ... Authors: Peisach, E, Allen, K.N. Deposit date: 2010-02-16 Release date: 2011-02-16 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Engineering encodable lanthanide-binding tags into loop regions of proteins. J.Am.Chem.Soc., 133, 2011
3NJ5	Crystal structure of chicken IL-1 hydrophobic cavity mutant 157 Descriptor: IL-1 beta Authors: Yin, H.S, Chen, Y.W. Deposit date: 2010-06-17 Release date: 2011-06-22 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.67 Å) Cite: Structural and functional comparison of cytokine interleukin-1 beta from chicken and human Mol.Immunol., 48, 2011
3POK	Interleukin-1-beta LBT L3 Mutant Descriptor: Interleukin-1 beta Authors: Barthelmes, K, Reynolds, A.M, Peisach, E, Jonker, H.R.A, DeNunzio, N.J, Allen, K.N, Imperiali, B, Schwalbe, H. Deposit date: 2010-11-22 Release date: 2011-01-19 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Engineering encodable lanthanide-binding tags into loop regions of proteins. J.Am.Chem.Soc., 133, 2011
1T4Q	Interleukin 1 beta F101W Descriptor: Interleukin-1 beta Authors: Adamek, D.H, Guerrero, L, Caspar, D.L. Deposit date: 2004-04-30 Release date: 2004-12-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural and energetic consequences of mutations in a solvated hydrophobic cavity. J.Mol.Biol., 346, 2005
1TOO	Interleukin 1B Mutant F146W Descriptor: Interleukin-1 beta Authors: Adamek, D.H, Guerrero, L, Caspar, D.L. Deposit date: 2004-06-14 Release date: 2004-12-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural and energetic consequences of mutations in a solvated hydrophobic cavity. J.Mol.Biol., 346, 2005
1TP0	Triple mutation in interleukin 1 beta cavity:replacement of phenylalanines with tryptophan. Descriptor: Interleukin-1 beta Authors: Adamek, D.H, Guerrero, L, Caspar, D.L. Deposit date: 2004-06-15 Release date: 2005-02-08 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural and energetic consequences of mutations in a solvated hydrophobic cavity. J.Mol.Biol., 346, 2005
1TWM	Interleukin-1 Beta Mutant F146Y Descriptor: Interleukin-1 beta Authors: Adamek, D.H, Capsar, D.L. Deposit date: 2004-07-01 Release date: 2004-12-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Structural and energetic consequences of mutations in a solvated hydrophobic cavity. J.Mol.Biol., 346, 2005
1TWE	INTERLEUKIN 1 BETA MUTANT F101Y Descriptor: Interleukin-1 beta Authors: Adamek, D.H, Capsar, D.L. Deposit date: 2004-06-30 Release date: 2004-12-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural and energetic consequences of mutations in a solvated hydrophobic cavity. J.Mol.Biol., 346, 2005
2I1B	CRYSTALLOGRAPHIC REFINEMENT OF INTERLEUKIN-1 BETA AT 2.0 ANGSTROMS RESOLUTION Descriptor: INTERLEUKIN-1 BETA Authors: Priestle, J.P, Schaer, H.-P, Gruetter, M.G. Deposit date: 1990-01-02 Release date: 1990-04-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystallographic refinement of interleukin 1 beta at 2.0 A resolution. Proc.Natl.Acad.Sci.USA, 86, 1989
2IRT	INITIAL CRYSTALLOGRAPHIC ANALYSES OF A RECOMBINANT INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN Descriptor: INTERLEUKIN-1 RECEPTOR ANTAGONIST Authors: Finzel, B.C, Clancy, L.L, Einspahr, H.M. Deposit date: 1994-07-13 Release date: 1994-10-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Initial crystallographic analysis of a recombinant human interleukin-1 receptor antagonist protein. Acta Crystallogr.,Sect.D, 50, 1994
2ILA	STRUCTURE OF INTERLEUKIN 1ALPHA AT 2.7-ANGSTROMS RESOLUTION Descriptor: INTERLEUKIN-1 ALPHA Authors: Graves, B.J, Hatada, M.H. Deposit date: 1991-05-01 Release date: 1992-10-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of interleukin 1 alpha at 2.7-A resolution. Biochemistry, 29, 1990
2KH2	Solution structure of a scFv-IL-1B complex Descriptor: Interleukin-1 beta, scFv Authors: Wilkinson, I.C, Hall, C.J, Veverka, V, Muskett, F.W, Stephens, P.E, Taylor, R.J, Henry, A.J, Carr, M.D. Deposit date: 2009-03-23 Release date: 2009-09-08 Last modified: 2022-03-16 Method: SOLUTION NMR Cite: High resolution NMR-based model for the structure of a scFv-IL-1beta complex: potential for NMR as a key tool in therapeutic antibody design and development. J.Biol.Chem., 284, 2009
2KKI	Solution structure of human Interleukin 1a Descriptor: Interleukin-1 alpha Authors: Mohan, S.K, Chang, H.-K, Yu, C. Deposit date: 2009-06-24 Release date: 2010-06-30 Last modified: 2022-03-16 Method: SOLUTION NMR Cite: 1H, 13C and 15N backbone and side chain resonance assignments of human interleukin 1alpha Biomol.Nmr Assign., 4, 2010
4X3A	gallus interleukin-1 beta mutant - R140A Descriptor: IL-1 beta Authors: Yin, H.S, Cheng, W.T. Deposit date: 2014-11-28 Release date: 2015-12-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.75 Å) Cite: gallus interleukin-1 beta mutant - R140A To Be Published
4X37	Gallus interleukin-1 mutant - E118K Descriptor: IL-1 beta Authors: Yin, H.S, Cheng, W.T, Cheng, T. Deposit date: 2014-11-28 Release date: 2015-12-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Gallus interleukin-1 mutant - E118K To Be Published

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