2LS7
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7PDJ
| R12E vFLIP mutant | 分子名称: | FLICE inhibitory protein | 著者 | Barrett, T.E. | 登録日 | 2021-08-05 | 公開日 | 2022-05-11 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Mechanistic insights into the activation of the IKK kinase complex by the Kaposi's sarcoma herpes virus oncoprotein vFLIP. J.Biol.Chem., 298, 2022
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4ZBW
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3CL3
| Crystal Structure of a vFLIP-IKKgamma complex: Insights into viral activation of the IKK signalosome | 分子名称: | NF-kappa-B essential modulator, ORF K13 | 著者 | Bagneris, C, Ageichik, A.V, Cronin, N, Boshoff, C, Waksman, G, Barrett, T. | 登録日 | 2008-03-18 | 公開日 | 2008-06-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of a vFlip-IKKgamma complex: insights into viral activation of the IKK signalosome. Mol.Cell, 30, 2008
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1N3K
| Solution structure of phosphoprotein enriched in astrocytes 15 kDa (PEA-15) | 分子名称: | Astrocytic phosphoprotein PEA-15 | 著者 | Hill, J.M, Vaidyanathan, H, Ramos, J.W, Ginsberg, M.H, Werner, M.H. | 登録日 | 2002-10-28 | 公開日 | 2003-01-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Recognition of ERK MAP Kinase by PEA-15 Reveals a Common Docking Site Within the Death Domain and Death Effector Domain Embo J., 21, 2002
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6AGW
| Pro-domain of Caspase-8 | 分子名称: | Caspase-8 pro-domain | 著者 | Park, H.H. | 登録日 | 2018-08-15 | 公開日 | 2019-06-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.093 Å) | 主引用文献 | Molecular basis of dimerization of initiator caspase was revealed by crystal structure of caspase-8 pro-domain. Cell Death Differ., 26, 2019
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7DEE
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6M6O
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6P6B
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6P6C
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5H31
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5H33
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1A1Z
| FADD DEATH EFFECTOR DOMAIN, F25G MUTANT, NMR MINIMIZED AVERAGE STRUCTURE | 分子名称: | FADD PROTEIN | 著者 | Eberstadt, M, Huang, B, Chen, Z, Meadows, R.P, Ng, C, Fesik, S.W. | 登録日 | 1997-12-18 | 公開日 | 1998-12-30 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure and mutagenesis of the FADD (Mort1) death-effector domain. Nature, 392, 1998
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1A1W
| FADD DEATH EFFECTOR DOMAIN, F25Y MUTANT, NMR MINIMIZED AVERAGE STRUCTURE | 分子名称: | FADD PROTEIN | 著者 | Eberstadt, M, Huang, B, Chen, Z, Meadows, R.P, Ng, C, Fesik, S.W. | 登録日 | 1997-12-18 | 公開日 | 1998-12-30 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure and mutagenesis of the FADD (Mort1) death-effector domain. Nature, 392, 1998
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7LVM
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7LVJ
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5L08
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7LXC
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2BBR
| Crystal Structure of MC159 Reveals Molecular Mechanism of DISC Assembly and vFLIP Inhibition | 分子名称: | AZIDE ION, Viral CASP8 and FADD-like apoptosis regulator | 著者 | Yang, J.K, Wang, L, Zheng, L, Wan, F, Ahmed, M, Lenardo, M.J, Wu, H. | 登録日 | 2005-10-17 | 公開日 | 2006-02-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition. Mol.Cell, 20, 2005
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2BBZ
| Crystal Structure of MC159 Reveals Molecular Mechanism of DISC Assembly and vFLIP Inhibition | 分子名称: | Viral CASP8 and FADD-like apoptosis regulator | 著者 | Yang, J.K, Wang, L, Zheng, L, Wan, F, Ahmed, M, Lenardo, M.J, Wu, H. | 登録日 | 2005-10-18 | 公開日 | 2006-02-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition. Mol.Cell, 20, 2005
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2F1S
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5JQE
| Crystal structure of caspase8 tDED | 分子名称: | Sugar ABC transporter substrate-binding protein,Caspase-8 chimera | 著者 | Fu, T, Li, Y, Lu, A, Wu, H. | 登録日 | 2016-05-04 | 公開日 | 2016-10-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.157 Å) | 主引用文献 | Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex. Mol. Cell, 64, 2016
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5LDE
| Crystal structure of a vFLIP-IKKgamma stapled peptide dimer | 分子名称: | Immunoglobulin G-binding protein G,Viral FLICE protein, Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, ... | 著者 | Barrett, T. | 登録日 | 2016-06-24 | 公開日 | 2017-10-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | 主引用文献 | IKK gamma-Mimetic Peptides Block the Resistance to Apoptosis Associated with Kaposi's Sarcoma-Associated Herpesvirus Infection. J. Virol., 91, 2017
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2GF5
| Structure of intact FADD (MORT1) | 分子名称: | FADD protein | 著者 | Carrington, P.E, Sandu, C, Wei, Y, Hill, J.M, Morisawa, G, Huang, T, Gavathiotis, E, Wei, Y, Werner, M.H. | 登録日 | 2006-03-21 | 公開日 | 2006-06-27 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | The Structure of FADD and Its Mode of Interaction with Procaspase-8 Mol.Cell, 22, 2006
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4IZ7
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