2BBZ
Crystal Structure of MC159 Reveals Molecular Mechanism of DISC Assembly and vFLIP Inhibition
Summary for 2BBZ
Entry DOI | 10.2210/pdb2bbz/pdb |
Related | 2BBR |
Descriptor | Viral CASP8 and FADD-like apoptosis regulator (2 entities in total) |
Functional Keywords | death effector domain, viral protein |
Biological source | Molluscum contagiosum virus subtype 1 |
Total number of polymer chains | 4 |
Total formula weight | 112155.73 |
Authors | Yang, J.K.,Wang, L.,Zheng, L.,Wan, F.,Ahmed, M.,Lenardo, M.J.,Wu, H. (deposition date: 2005-10-18, release date: 2006-02-14, Last modification date: 2024-02-14) |
Primary citation | Yang, J.K.,Wang, L.,Zheng, L.,Wan, F.,Ahmed, M.,Lenardo, M.J.,Wu, H. Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition. Mol.Cell, 20:939-949, 2005 Cited by PubMed: 16364918DOI: 10.1016/j.molcel.2005.10.023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.8 Å) |
Structure validation
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