PDB: 150 件ウェブページステータス検索Chemie searchBIRD

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3JWA	Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with methionine phosphinate 分子名称: (1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC ACID, DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase 著者 Revtovish, S.V, Nikulin, A.D, Morozova, E.A, Demidkina, T.V. 登録日 2009-09-18 公開日 2010-09-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Three-dimensional structures of noncovalent complexes of Citrobacter freundii methionine gamma-lyase with substrates. Biochemistry Mosc., 76, 2011
5M3Z	Crystal structure of Citrobacter freundii methionine gamma-lyase with C115H replacement in the complex with L-norleucine 分子名称: 2-[O-PHOSPHONOPYRIDOXYL]-AMINO-HEXANOIC ACID, Methionine gamma-lyase, NORLEUCINE, ... 著者 Revtovich, S.V, Nikulin, A.D, Anufrieva, N.V, Morozova, E.A, Demidkina, T.V. 登録日 2016-10-17 公開日 2017-06-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of mutant form Cys115His of Citrobacter freundii methionine gamma-lyase complexed with l-norleucine. Biochim. Biophys. Acta, 1865, 2017
5K30	Crystal structure of methionine gamma-lyase from Citrobacter freundii modified by S-Ethyl-L-cysteine sulfoxide 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase, ... 著者 Revtovich, S.V, Nikulin, A.D, Morozova, E.A, Demidkina, T.V. 登録日 2016-05-19 公開日 2017-07-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Sulfoxides of sulfur-containing amino acids are suicide substrates of Citrobacter freundii methionine gamma-lyase. Structural bases of the enzyme inactivation. Biochimie, 168, 2020
7SWH	Crystal Structure of Putative cystathionine gamma-synthase from Burkholderia pseudomallei in Complex with PLP 分子名称: 1,2-ETHANEDIOL, Putative cystathionine gamma-synthase 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-11-19 公開日 2021-12-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of Putative cystathionine gamma-synthase from Burkholderia pseudomallei in Complex with PLP to be published
2RFV	High resolution structure of L-methionine gamma-lyase from Citrobacter freundii 分子名称: CHLORIDE ION, Methionine gamma-lyase 著者 Nikulin, A.D, Revtovich, S.V, Morozova, E.A, Nevskaya, N.A, Nikonov, S.V, Garber, M.B, Demidkina, T.V. 登録日 2007-10-02 公開日 2008-08-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.355 Å) 主引用文献 High-resolution structure of methionine gamma-lyase from Citrobacter freundii. Acta Crystallogr.,Sect.D, 64, 2008
4XQ2	Ensemble refinement of cystathione gamma lyase (CalE6) D7G from Micromonospora echinospora 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, CalE6, ... 著者 Wang, F, Yennamalli, R.M, Singh, S, Tan, K, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) 登録日 2015-01-18 公開日 2015-04-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The crystal structure of cystathione gamma lyase (CalE6) from Micromonospora echinospora To Be Published
5IJG	Crystal structure of O-acetylhomoserine sulfhydrolase from Brucella melitensis at 2.0 A resolution 分子名称: Cys/Met metabolism pyridoxal-phosphate-dependent enzyme, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE 著者 Boyko, K.M, Nikolaeva, A.Y, Koolikova, V.V, Kotlov, M.I, Demidkina, T.V, Popov, V.O. 登録日 2016-03-02 公開日 2017-04-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of O-acetylhomoserine sulfhydrolase from Brucella melitensis at 2.0 A resolution To Be Published
3MKJ	Methionine gamma-lyase from Citrobacter freundii with pyridoximine-5'-phosphate 分子名称: Methionine gamma-lyase, [5-hydroxy-4-(iminomethyl)-6-methyl-pyridin-3-yl]methyl dihydrogen phosphate 著者 Revtovich, S.V, Nikulin, A.D, Morozova, E.A, Demidkina, T.V. 登録日 2010-04-15 公開日 2010-08-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Exploring methionine gamma-lyase structure-function relationship via microspectrophotometry and X-ray crystallography Biochim.Biophys.Acta, 1814, 2011
8DUY	Crystal structure of Cystathionine beta-lyase from Klebsiella pneumoniae 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Cystathionine beta-lyase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2022-07-27 公開日 2022-08-10 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of Cystathionine beta-lyase from Klebsiella pneumoniae To be Published
6S0C	Crystal structure of methionine gamma-lyase from Citrobacter freundii modified by dimethylthiosulfinate 分子名称: Cystathionine gamma-synthase, PYRIDOXAL-5'-PHOSPHATE, TRIETHYLENE GLYCOL 著者 Revtovich, S.V, Morozova, E.A, Nikulin, A.D, Demidkina, T.V. 登録日 2019-06-14 公開日 2020-04-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Sulfoxides of sulfur-containing amino acids are suicide substrates of Citrobacter freundii methionine gamma-lyase. Structural bases of the enzyme inactivation. Biochimie, 168, 2020
7YEO	Crystal Structure of cystathionine gamma-synthase-like protein C23A1.14c 分子名称: MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, Uncharacterized trans-sulfuration enzyme C23A1.14c 著者 Zhang, S.J. 登録日 2022-07-06 公開日 2023-01-11 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of cystathionine gamma-synthase-like protein C23A1.14c To Be Published
1UKJ	Detailed structure of L-Methionine-Lyase from Pseudomonas putida 分子名称: Methionine gamma-lyase, SULFATE ION 著者 Misaki, S, Takimoto, A, Takakura, T, Yoshioka, T, Yamashita, M, Tamura, T, Tanaka, H, Inagaki, K. 登録日 2003-08-24 公開日 2004-10-19 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Detailed structure of L-Methionine -Lyase from Pseudomonas putida To be Published
8J6N	Crystal structure of Cystathionine gamma-lyase in complex with compound 1 分子名称: 1,2-ETHANEDIOL, Cystathionine gamma-lyase, GLYCEROL, ... 著者 Hibi, R, Toma-Fukai, S, Shimizu, T, Hanaoka, K. 登録日 2023-04-26 公開日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of a cystathionine gamma-lyase (CSE) selective inhibitor targeting active-site pyridoxal 5'-phosphate (PLP) via Schiff base formation. Sci Rep, 13, 2023
1Y4I	Crystal structure of Citrobacter Freundii L-methionine-lyase 分子名称: SULFATE ION, methionine gamma-lyase 著者 Revtovich, S.V, Mamaeva, D.V, Morozova, E.A, Nikulin, A.D, Nikonov, S.V, Garber, M.B, Demidkina, T.V. 登録日 2004-12-01 公開日 2005-06-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of Citrobacter freundii L-methionine gamma-lyase. Acta Crystallogr.,Sect.F, 61, 2005
5X5H	Crystal structure of metB from Corynebacterium glutamicum 分子名称: Cystathionine beta-lyases/cystathionine gamma-synthases, GLYCEROL, MAGNESIUM ION, ... 著者 Sagong, H.-Y, Kim, K.-J. 登録日 2017-02-16 公開日 2017-03-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Structural Insights into Substrate Specificity of Cystathionine gamma-Synthase from Corynebacterium glutamicum J. Agric. Food Chem., 65, 2017
5X2X	Crystal structure of Pseudomonas putida methionine gamma-lyase wild type with L-homocysteine intermediates 分子名称: (2E)-2-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}but-2-enoic acid, HYDROSULFURIC ACID, L-methionine gamma-lyase 著者 Shiba, T, Sato, D, Harada, S. 登録日 2017-02-02 公開日 2017-04-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and mechanistic insights into homocysteine degradation by a mutant of methionine gamma-lyase based on substrate-assisted catalysis Protein Sci., 26, 2017
5TT2	Inactive conformation of engineered human cystathionine gamma lyase (E59N, R119L, E339V) to depleting methionine 分子名称: Cystathionine gamma-lyase, SULFATE ION 著者 Yan, W, Zhang, Y. 登録日 2016-10-31 公開日 2017-10-11 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (2.949 Å) 主引用文献 Structural Snapshots of an Engineered Cystathionine-gamma-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site. Biochemistry, 56, 2017
6NBA	Crystal structure of Human Cystathionine gamma lyase with S-3-Carboxpropyl-L-Cysteine 分子名称: 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, Cystathionine gamma-lyase 著者 Kim, H, Yadav, P.K, Banerjee, R, Cho, U.-S. 登録日 2018-12-06 公開日 2019-06-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.495 Å) 主引用文献 S-3-Carboxypropyl-l-cysteine specifically inhibits cystathionine gamma-lyase-dependent hydrogen sulfide synthesis. J.Biol.Chem., 294, 2019
8JUI	Crystal structures of Cystathionine beta lyase from Bacillus cereus ATCC 14579 分子名称: Cystathionine beta-lyase, PYRIDOXAL-5'-PHOSPHATE 著者 Yu, H, Kim, K.-J. 登録日 2023-06-26 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of Cystathionine beta lyase from Bacillus cereus ATCC 14579 To Be Published
2FQ6	Cystathionine beta-lyase (cbl) from escherichia coli in complex with n-hydrazinocarbonylmethyl-2-trifluoromethyl-benzamide 分子名称: Cystathionine beta-lyase, PHOSPHORIC ACID MONO-(5-HYDROXY-6-METHYL-4-{[2-(2-TRIFLUOROMETHYL-BENZOYLAMINO)-ACETYL]-HYDRAZONOMETHYL}-PYRIDIN-3-YLMETHYL)ESTER 著者 Junop, M.S. 登録日 2006-01-17 公開日 2006-12-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Inhibitors of bacterial cystathionine beta-lyase: leads for new antimicrobial agents and probes of enzyme structure and function. J.Med.Chem., 50, 2007
2CB1	Crystal Structure of O-actetyl Homoserine Sulfhydrylase From Thermus Thermophilus HB8,OAH2. 分子名称: O-ACETYL HOMOSERINE SULFHYDRYLASE, PYRIDOXAL-5'-PHOSPHATE 著者 Imagawa, T, Utsunomiya, H, Tsuge, H, Ebihara, A, Kanagawa, M, Nakagawa, N, Kuroishi, C, Agari, Y, Kuramitsu, S, Yokoyama, S. 登録日 2005-12-28 公開日 2007-01-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Crystal Structure of O-Acetyl Homoserine Sulfhydrylase To be Published
8OVH	Crystal structure of O-acetyl-L-homoserine sulfhydrolase from Saccharomyces cerevisiae in complex with Pyridoxal-5'-phosphate 分子名称: DI(HYDROXYETHYL)ETHER, Homocysteine/cysteine synthase, PYRIDOXAL-5'-PHOSPHATE 著者 Saleem-Batcha, R, Andexer, J.N, Mohr, M. 登録日 2023-04-26 公開日 2023-06-21 最終更新日 2024-09-18 実験手法 X-RAY DIFFRACTION (2.171 Å) 主引用文献 Structure, function and substrate preferences of archaeal S-adenosyl-L-homocysteine hydrolases. Commun Biol, 7, 2024
6OVG	L-Methionine Depletion with an Engineered Human Enzyme Disrupts Prostate Cancer Metabolism 分子名称: Cystathionine gamma-lyase, SULFATE ION 著者 Yan, W, Irani, S, Zhang, J. 登録日 2019-05-07 公開日 2020-04-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.719 Å) 主引用文献 Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity. Proc.Natl.Acad.Sci.USA, 117, 2020
2O7C	Crystal structure of L-methionine-lyase from Pseudomonas 分子名称: Methionine gamma-lyase, SULFATE ION 著者 Misaki, S, Takimoto, A, Takakura, T, Yoshioka, T, Yamashita, M, Tamura, T, Tanaka, H, Inagaki, K. 登録日 2006-12-10 公開日 2007-12-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of the antitumour enzyme L-methionine gamma-lyase from Pseudomonas putida at 1.8 A resolution J.Biochem.(Tokyo), 141, 2007
5TSU	Active conformation for Engineered human cystathionine gamma lyase (E59N, R119L, E339V) to depleting methionine 分子名称: CYSTEINE, Cystathionine gamma-lyase, METHIONINE, ... 著者 Yan, W, Zhang, Y. 登録日 2016-10-31 公開日 2017-10-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Snapshots of an Engineered Cystathionine-gamma-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site. Biochemistry, 56, 2017

 

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