2FQ6

Cystathionine beta-lyase (cbl) from escherichia coli in complex with n-hydrazinocarbonylmethyl-2-trifluoromethyl-benzamide

Summary for 2FQ6

Entry DOI	10.2210/pdb2fq6/pdb
Descriptor	Cystathionine beta-lyase, PHOSPHORIC ACID MONO-(5-HYDROXY-6-METHYL-4-{[2-(2-TRIFLUOROMETHYL-BENZOYLAMINO)-ACETYL]-HYDRAZONOMETHYL}-PYRIDIN-3-YLMETHYL)ESTER (3 entities in total)
Functional Keywords	protein-inhibitor complex, plp cofactor covalently bound to p3f inhibitor, lyase
Biological source	Escherichia coli
Cellular location	Cytoplasm: P06721
Total number of polymer chains	2
Total formula weight	91845.91
Authors	Junop, M.S. (deposition date: 2006-01-17, release date: 2006-12-26, Last modification date: 2023-08-30)
Primary citation	Ejim, L.J.,Blanchard, J.E.,Koteva, K.P.,Sumerfield, R.,Elowe, N.H.,Chechetto, J.D.,Brown, E.D.,Junop, M.S.,Wright, G.D. Inhibitors of bacterial cystathionine beta-lyase: leads for new antimicrobial agents and probes of enzyme structure and function. J.Med.Chem., 50:755-764, 2007 Cited by PubMed: 17300162 DOI: 10.1021/jm061132r PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.78 Å)

Structure validation