5TSN
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5XE0
| Crystal structure of EV-D68-3Dpol in complex with GTP | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein | 著者 | Xie, W, Wang, C, Wang, Z, Li, Q, Wang, C. | 登録日 | 2017-03-30 | 公開日 | 2017-06-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure and Thermostability Characterization of Enterovirus D68 3Dpol J. Virol., 91, 2017
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3KMS
| G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA trigonal structure | 分子名称: | 3D polymerase, MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), ... | 著者 | Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. | 登録日 | 2009-11-11 | 公開日 | 2010-07-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin J.Virol., 84, 2010
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5JXS
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7W9S
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8C2P
| FMDV 3D polymerase in complex with 3B3 | 分子名称: | Protein 3B-3, RNA-directed RNA polymerase 3D-POL | 著者 | Ferrer-Orta, C, Veraguer, N. | 登録日 | 2022-12-22 | 公開日 | 2023-04-26 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes. Plos Pathog., 19, 2023
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8C1N
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1HHS
| RNA dependent RNA polymerase from dsRNA bacteriophage phi6 | 分子名称: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | 著者 | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | 登録日 | 2000-12-28 | 公開日 | 2001-03-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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1HHT
| RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus template | 分子名称: | DNA (5'-(*TP*TP*TP*CP*C)-3'), MANGANESE (II) ION, P2 PROTEIN | 著者 | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | 登録日 | 2000-12-28 | 公開日 | 2001-03-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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3H5Y
| Norovirus polymerase+primer/template+CTP complex at 6 mM MnCl2 | 分子名称: | 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', CYTIDINE-5'-TRIPHOSPHATE, ... | 著者 | Zamyatkin, D.F, Parra, F, Machin, A, Grochulski, P, Ng, K.K.S. | 登録日 | 2009-04-22 | 公開日 | 2009-05-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site. J.Mol.Biol., 390, 2009
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3H5X
| Crystal Structure of 2'-amino-2'-deoxy-cytidine-5'-triphosphate bound to Norovirus GII RNA polymerase | 分子名称: | 2'-amino-2'-deoxycytidine 5'-(tetrahydrogen triphosphate), 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', ... | 著者 | Zamyatkin, D.F, Parra, F, Machin, A, Grochulski, P, Ng, K.K.S. | 登録日 | 2009-04-22 | 公開日 | 2009-05-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site. J.Mol.Biol., 390, 2009
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4R0E
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5N8X
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5N95
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4QPX
| NV polymerase post-incorporation-like complex | 分子名称: | GLYCEROL, MANGANESE (II) ION, Polyprotein, ... | 著者 | Zamyatkin, D.F, Parra, F, Grochulski, P, Ng, K.K.S. | 登録日 | 2014-06-25 | 公開日 | 2015-04-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structure of a backtracked state reveals conformational changes similar to the state following nucleotide incorporation in human norovirus polymerase. Acta Crystallogr.,Sect.D, 70, 2014
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6GVV
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6GVY
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5I62
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5I61
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3BSN
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3BSO
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4Y34
| Crystal Structure of Coxsackievirus B3 3D polymerase in complex with GPC-N143 | 分子名称: | 2,2'-[(4-fluorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), 3D polymerase, GLYCEROL, ... | 著者 | Vives-Adrian, L, Ferrer-Orta, C, Cerdaguer, N. | 登録日 | 2015-02-10 | 公開日 | 2015-04-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family. Plos Pathog., 11, 2015
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4Y3C
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4Y2C
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3CDU
| Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with a pyrophosphate | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B. | 登録日 | 2008-02-27 | 公開日 | 2008-07-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases J.Virol., 82, 2008
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