1EQF
 
 | | CRYSTAL STRUCTURE OF THE DOUBLE BROMODOMAIN MODULE FROM HUMAN TAFII250 | | 分子名称: | RNA POLYMERASE II TRANSCRIPTION INITIATION FACTOR, SULFATE ION | | 著者 | Jacobson, R.H, Ladurner, A.G, King, D.S, Tjian, R. | | 登録日 | 2000-04-04 | | 公開日 | 2000-06-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure and function of a human TAFII250 double bromodomain module.
Science, 288, 2000
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1E6I
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1F68
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1JM4
 | | NMR Structure of P/CAF Bromodomain in Complex with HIV-1 Tat Peptide | | 分子名称: | HIV-1 Tat Peptide, P300/CBP-associated Factor | | 著者 | Mujtaba, S, He, Y, Zeng, L, Farooq, A, Carlson, J.E, Ott, M, Verdin, E, Zhou, M.-M. | | 登録日 | 2001-07-17 | | 公開日 | 2002-07-17 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain
Mol.Cell, 9, 2002
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1JSP
 | | NMR Structure of CBP Bromodomain in complex with p53 peptide | | 分子名称: | CREB-BINDING PROTEIN, tumor protein p53 | | 著者 | He, Y, Mujtaba, S, Zeng, L, Yan, S, Zhou, M.-M. | | 登録日 | 2001-08-17 | | 公開日 | 2002-08-17 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation.
Mol.Cell, 13, 2004
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1N72
 | | Structure and Ligand of a Histone Acetyltransferase Bromodomain | | 分子名称: | HISTONE ACETYLTRANSFERASE | | 著者 | Dhalluin, C, Carlson, J.E, Zeng, L, He, C, Aggarwal, A.K, Zhou, M.-M. | | 登録日 | 2002-11-12 | | 公開日 | 2002-12-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and Ligand of a Histone Acetyltransferase Bromodomain
Nature, 399, 1999
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1WUG
 | | complex structure of PCAF bromodomain with small chemical ligand NP1 | | 分子名称: | Histone acetyltransferase PCAF, N-(3-AMINOPROPYL)-4-METHYL-2-NITROBENZENAMINE | | 著者 | Zeng, L, Li, J, Muller, M, Yan, S, Mujtaba, S, Pan, C, Wang, Z, Zhou, M.M. | | 登録日 | 2004-12-07 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Selective small molecules blocking HIV-1 Tat and coactivator PCAF association
J.Am.Chem.Soc., 127, 2005
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1WUM
 | | Complex structure of PCAF bromodomain with small chemical ligand NP2 | | 分子名称: | Histone acetyltransferase PCAF, N-(3-AMINOPROPYL)-2-NITROBENZENAMINE | | 著者 | Zeng, L, Li, J, Muller, M, Yan, S, Mujtaba, S, Pan, C, Wang, Z, Zhou, M.M. | | 登録日 | 2004-12-08 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Selective small molecules blocking HIV-1 Tat and coactivator PCAF association
J.Am.Chem.Soc., 127, 2005
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2D82
 | | Target Structure-Based Discovery of Small Molecules that Block Human p53 and CREB Binding Protein (CBP) Association | | 分子名称: | 9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE, CREB-binding protein | | 著者 | Sachchidanand, Resnick-Silverman, L, Yan, S, Mujtaba, S, Liu, W.J, Zeng, L, Manfredi, J.J, Zhou, M.M. | | 登録日 | 2005-12-01 | | 公開日 | 2006-04-04 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Target structure-based discovery of small molecules that block human p53 and CREB binding protein association
Chem.Biol., 13, 2006
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1ZS5
 | | Structure-based evaluation of selective and non-selective small molecules that block HIV-1 TAT and PCAF association | | 分子名称: | (3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE, Histone acetyltransferase PCAF | | 著者 | Zeng, L, Godbole, S, Muller, M, Yan, S, Sanchez, R, Zhou, M. | | 登録日 | 2005-05-23 | | 公開日 | 2006-05-23 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure-based evaluation of selective nad non-selective small molecules that block hiv-1 tat and pcaf association
TO BE PUBLISHED
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2D9E
 | | Solution structure of the Bromodomain of Peregrin | | 分子名称: | Peregrin | | 著者 | Hatta, R, Hayashi, F, Izumi, K, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-12-09 | | 公開日 | 2006-06-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the Bromodomain of Peregrin
To be published
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1X0J
 | | Crystal structure analysis of the N-terminal bromodomain of human Brd2 | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bromodomain-containing protein 2 | | 著者 | Nakamura, Y, Umehara, T, Shirouzu, M, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-03-23 | | 公開日 | 2006-06-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for acetylated histone H4 recognition by the human Brd2 bromodomain
To be Published
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2FSA
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2F6J
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2F6N
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2DKW
 | | Solution structure of the bromodomain of human protein KIAA1240 | | 分子名称: | hypothetical protein KIAA1240 | | 著者 | Sano, R, Hayashi, F, Kurosaki, C, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-14 | | 公開日 | 2006-10-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the bromodomain of human protein KIAA1240
To be Published
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2NXB
 | | Crystal structure of human Bromodomain containing protein 3 (BRD3) | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 3, SODIUM ION | | 著者 | Filippakopoulos, P, Bullock, A, Cooper, C, Keates, K, Berridge, G, Pike, A, Bunkoczi, G, Edwards, A, Arrowsmith, C, Sundstrom, M, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2006-11-17 | | 公開日 | 2006-12-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
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2DAT
 | | Solution structure of the Bromodomain of human SWI/SNF related matrix associated actin dependent regulator of cromatin subfamily A member 2 | | 分子名称: | Possible global transcription activator SNF2L2 | | 著者 | Yoneyama, M, Kigawa, T, Saito, K, Tochio, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-12-14 | | 公開日 | 2007-01-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the Bromodomain of human SWI/SNF related matrix associated actin dependent regulator of cromatin subfamily A member 2
To be Published
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2OO1
 | | Crystal structure of the Bromo domain 2 of human Bromodomain containing protein 3 (BRD3) | | 分子名称: | 1,2-ETHANEDIOL, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, Bromodomain-containing protein 3, ... | | 著者 | Filippakopoulos, P, Bullock, A, Papagrigoriou, E, Keates, T, Cooper, C, Smee, C, Ugochukwu, E, Debreczeni, J, von Delft, F, Arrowsmith, C, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2007-01-25 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
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2H60
 | | Solution Structure of Human Brg1 Bromodomain | | 分子名称: | Probable global transcription activator SNF2L4 | | 著者 | Shen, W, Xu, C, Zhang, J, Wu, J, Shi, Y. | | 登録日 | 2006-05-30 | | 公開日 | 2007-02-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of human Brg1 bromodomain and its specific binding to acetylated histone tails
Biochemistry, 46, 2007
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2OSS
 | | Crystal structure of the Bromo domain 1 in human Bromodomain Containing Protein 4 (BRD4) | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | | 著者 | Filippakopoulos, P, Keates, T, Savitsky, P, Burgess, N, Pike, A.C.W, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2007-02-06 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
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2OUO
 | | Crystal Structure of the Bromo domain 2 in human Bromodomain Containing Protein 4 (BRD4) | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | | 著者 | Filippakopoulos, P, Keates, T, Savitsky, P, Burgess, N, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2007-02-12 | | 公開日 | 2007-02-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
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2G4A
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2GRC
 | | 1.5 A structure of bromodomain from human BRG1 protein, a central ATPase of SWI/SNF remodeling complex | | 分子名称: | Probable global transcription activator SNF2L4 | | 著者 | Singh, M, Popowicz, G.M, Krajewski, M, Holak, T.A. | | 登録日 | 2006-04-24 | | 公開日 | 2007-05-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural ramification for acetyl-lysine recognition by the bromodomain of human BRG1 protein, a central ATPase of the SWI/SNF remodeling complex.
Chembiochem, 8, 2007
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2I7K
 | | Solution Structure of the Bromodomain of Human BRD7 Protein | | 分子名称: | Bromodomain-containing protein 7 | | 著者 | Sun, H, Liu, J, Zhang, J, Huang, H, Wu, J, Shi, Y. | | 登録日 | 2006-08-31 | | 公開日 | 2007-07-10 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of BRD7 bromodomain and its interaction with acetylated peptides from histone H3 and H4
Biochem.Biophys.Res.Commun., 358, 2007
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