1ZS5
Structure-based evaluation of selective and non-selective small molecules that block HIV-1 TAT and PCAF association
Summary for 1ZS5
Entry DOI | 10.2210/pdb1zs5/pdb |
Related | 1WUG 1WUM |
NMR Information | BMRB: 6507,6508 |
Descriptor | Histone acetyltransferase PCAF, (3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE (2 entities in total) |
Functional Keywords | bromodomain, histone-acetyltransferase, nmr-structure chemical ligand, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (By similarity): Q92831 |
Total number of polymer chains | 1 |
Total formula weight | 14251.47 |
Authors | Zeng, L.,Godbole, S.,Muller, M.,Yan, S.,Sanchez, R.,Zhou, M. (deposition date: 2005-05-23, release date: 2006-05-23, Last modification date: 2024-05-22) |
Primary citation | Zeng, L.,Godbole, S.,Muller, M.,Yan, S.,Sanchez, R.,Zhou, M. Structure-based evaluation of selective nad non-selective small molecules that block hiv-1 tat and pcaf association TO BE PUBLISHED, |
Experimental method | SOLUTION NMR |
Structure validation
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