2OO1
Crystal structure of the Bromo domain 2 of human Bromodomain containing protein 3 (BRD3)
Summary for 2OO1
Entry DOI | 10.2210/pdb2oo1/pdb |
Descriptor | Bromodomain-containing protein 3, SODIUM ION, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | brd3, bromodomain containing protein 3, orfx, ring3 like gene, ring3l, structural genomics, structural genomics consortium, sgc, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : Q15059 |
Total number of polymer chains | 4 |
Total formula weight | 54144.57 |
Authors | Filippakopoulos, P.,Bullock, A.,Papagrigoriou, E.,Keates, T.,Cooper, C.,Smee, C.,Ugochukwu, E.,Debreczeni, J.,von Delft, F.,Arrowsmith, C.,Edwards, A.,Weigelt, J.,Sundstrom, M.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2007-01-25, release date: 2007-02-13, Last modification date: 2023-08-30) |
Primary citation | Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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