1WUM

Complex structure of PCAF bromodomain with small chemical ligand NP2

Summary for 1WUM

• Entry DOI: 10.2210/pdb1wum/pdb
• Related: 1JM4 1WUG 1b91
• NMR Information: BMRB: 6507
• Descriptor: Histone acetyltransferase PCAF, N-(3-AMINOPROPYL)-2-NITROBENZENAMINE (2 entities in total)
• Functional Keywords: bromodomain, histone-acetyltransferase, nmr-structure, chemical ligand, np2, np1, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus (By similarity): Q92831
• Total number of polymer chains: 1
• Total formula weight: 14247.44

Authors

Zeng, L.,Li, J.,Muller, M.,Yan, S.,Mujtaba, S.,Pan, C.,Wang, Z.,Zhou, M.M. (deposition date: 2004-12-08, release date: 2005-08-16, Last modification date: 2022-03-02)

• Primary citation: Zeng, L.,Li, J.,Muller, M.,Yan, S.,Mujtaba, S.,Pan, C.,Wang, Z.,Zhou, M.M.; Selective small molecules blocking HIV-1 Tat and coactivator PCAF association; J.Am.Chem.Soc., 127:2376-2377, 2005; PubMed: 15724976; DOI: 10.1021/ja044885g

Experimental method

SOLUTION NMR