2NXB

Crystal structure of human Bromodomain containing protein 3 (BRD3)

Summary for 2NXB

Entry DOI	10.2210/pdb2nxb/pdb
Descriptor	Bromodomain-containing protein 3, SODIUM ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	brd3, bromodomain containing protein 3, orfx, ring3 like gene, ring3l, structural genomics, structural genomics consortium, sgc, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Nucleus : Q15059
Total number of polymer chains	2
Total formula weight	29631.15
Authors	Filippakopoulos, P.,Bullock, A.,Cooper, C.,Keates, K.,Berridge, G.,Pike, A.,Bunkoczi, G.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,von Delft, F.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2006-11-17, release date: 2006-12-12, Last modification date: 2023-08-30)
Primary citation	Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331 DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation