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1GXR
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BU of 1gxr by Molmil
WD40 Region of Human Groucho/TLE1
分子名称: CALCIUM ION, TRANSDUCIN-LIKE ENHANCER PROTEIN 1
著者Pearl, L.H, Roe, S.M, Pickles, L.M.
登録日2002-04-10
公開日2002-06-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal Structure of the C-Terminal Wd40 Repeat Domain of the Human Groucho/Tle1 Transcriptional Corepressor
Structure, 10, 2002
4LG9
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BU of 4lg9 by Molmil
Crystal structure of TBL1XR1 WD40 repeats
分子名称: F-box-like/WD repeat-containing protein TBL1XR1, UNKNOWN ATOM OR ION
著者Xu, C, Tempel, W, He, H, Wu, X, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2013-06-27
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Crystal structure of TBL1XR1 WD40 repeats
TO BE PUBLISHED
4LG8
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BU of 4lg8 by Molmil
Crystal structure of PRPF19 WD40 repeats
分子名称: Pre-mRNA-processing factor 19, SODIUM ION, UNKNOWN ATOM OR ION
著者Xu, C, Tempel, W, He, H, Dobrovetsky, E, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2013-06-27
公開日2013-08-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal structure of the WD40 domain of human PRPF19.
Biochem. Biophys. Res. Commun., 493, 2017
2XL3
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BU of 2xl3 by Molmil
WDR5 IN COMPLEX WITH AN RBBP5 PEPTIDE AND HISTONE H3 PEPTIDE
分子名称: GLYCEROL, HISTONE H3.1, RETINOBLASTOMA-BINDING PROTEIN 5, ...
著者Odho, Z, Southall, S.M, Wilson, J.R.
登録日2010-07-19
公開日2010-08-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Characterisation of a Novel Wdr5 Binding Site that Recruits Rbbp5 Through a Conserved Motif and Enhances Methylation of H3K4 by Mll1.
J.Biol.Chem., 285, 2010
1YFQ
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BU of 1yfq by Molmil
High resolution S. cerevisiae Bub3 mitotic checkpoint protein
分子名称: ACETATE ION, CALCIUM ION, Cell cycle arrest protein BUB3
著者Wilson, D.K, Cerna, D, Chew, E.
登録日2005-01-03
公開日2005-01-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The 1.1-a structure of the spindle checkpoint protein bub3p reveals functional regions.
J.Biol.Chem., 280, 2005
4CY1
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BU of 4cy1 by Molmil
Crystal structure of the KANSL1-WDR5 complex.
分子名称: GLYCEROL, KAT8 REGULATORY NSL COMPLEX SUBUNIT 1, WD REPEAT-CONTAINING PROTEIN 5
著者Dias, J, Brettschneider, J, Cusack, S, Kadlec, J.
登録日2014-04-09
公開日2014-05-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Genes Dev., 28, 2014
4CY2
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BU of 4cy2 by Molmil
Crystal structure of the KANSL1-WDR5-KANSL2 complex.
分子名称: KAT8 REGULATORY NSL COMPLEX SUBUNIT 1, KAT8 REGULATORY NSL COMPLEX SUBUNIT 2, WD REPEAT-CONTAINING PROTEIN 5
著者Dias, J, Brettschneider, J, Cusack, S, Kadlec, J.
登録日2014-04-09
公開日2014-05-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Genes Dev., 28, 2014
4CY5
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BU of 4cy5 by Molmil
Crystal structure of the NSL1-WDS-NSL2 complex.
分子名称: CG4699, ISOFORM D, DIM GAMMA-TUBULIN 1, ...
著者Dias, J, Brettschneider, J, Cusack, S, Kadlec, J.
登録日2014-04-10
公開日2014-05-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Genes Dev., 28, 2014
1ERJ
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BU of 1erj by Molmil
CRYSTAL STRUCTURE OF THE C-TERMINAL WD40 DOMAIN OF TUP1
分子名称: TRANSCRIPTIONAL REPRESSOR TUP1
著者Sprague, E.R, Redd, M.J, Johnson, A.D, Wolberger, C.
登録日2000-04-06
公開日2000-07-26
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast.
EMBO J., 19, 2000
6IAM
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BU of 6iam by Molmil
Modulating Protein-Protein Interactions with Visible Light Peptide Backbone Switches
分子名称: POTASSIUM ION, SER-ALA-ARG-ALA-XY5-VAL-HIS-LEU-ARG-LYS-SER-ALA, SODIUM ION, ...
著者Werel, L, Essen, L.-O.
登録日2018-11-27
公開日2019-02-06
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Modulating Protein-Protein Interactions with Visible-Light-Responsive Peptide Backbone Photoswitches.
Chembiochem, 20, 2019
2CE9
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BU of 2ce9 by Molmil
A WRPW peptide bound to the Groucho-TLE WD40 domain.
分子名称: TRANSDUCIN-LIKE ENHANCER PROTEIN 1, WRPW PEPTIDE
著者Pickles, L.M, Roe, S.M, Pearl, L.H.
登録日2006-02-03
公開日2006-06-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Molecular Recognition of Transcriptional Repressor Motifs by the Wd Domain of the Groucho/Tle Corepressor.
Mol.Cell, 22, 2006
2CNX
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BU of 2cnx by Molmil
WDR5 and Histone H3 Lysine 4 dimethyl complex at 2.1 angstrom
分子名称: HISTONE H3 DIMETHYL-LYSINE 4, WD-REPEAT PROTEIN 5
著者Ruthenburg, A.J, Wang, W, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-25
公開日2006-07-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Histone H3 Recognition and Presentation by the Wdr5 Module of the Mll1 Complex
Nat.Struct.Mol.Biol., 13, 2006
2CE8
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BU of 2ce8 by Molmil
An EH1 peptide bound to the Groucho-TLE WD40 domain.
分子名称: EH1 PEPTIDE, TRANSDUCIN-LIKE ENHANCER PROTEIN 1
著者Pickles, L.M, Roe, S.M, Pearl, L.H.
登録日2006-02-03
公開日2006-06-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Molecular Recognition of Transcriptional Repressor Motifs by the Wd Domain of the Groucho/Tle Corepressor.
Mol.Cell, 22, 2006
2CO0
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BU of 2co0 by Molmil
WDR5 and unmodified Histone H3 complex at 2.25 Angstrom
分子名称: HISTONE H3 DIMETHYL-LYSINE 4, WD-REPEAT PROTEIN 5
著者Ruthenburg, A.J, Wang, W, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-25
公開日2006-07-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Histone H3 Recognition and Presentation by the Wdr5 Module of the Mll1 Complex
Nat.Struct.Mol.Biol., 13, 2006
5M23
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BU of 5m23 by Molmil
Modulation of MLL1 Methyltransferase Activity
分子名称: 4-[(~{E})-[4-[[[(2~{S})-2-[[(2~{S})-2-[[(2~{S})-2-[[(2~{S})-2-azanyl-3-oxidanyl-propanoyl]amino]propanoyl]amino]-5-carbamimidamido-pentanoyl]amino]propanoyl]amino]methyl]phenyl]diazenyl]-~{N}-[(2~{S})-3-methyl-1-oxidanylidene-butan-2-yl]benzamide, WD repeat-containing protein 5
著者Srinivasan, V.
登録日2016-10-11
公開日2017-06-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Controlled inhibition of methyltransferases using photoswitchable peptidomimetics: towards an epigenetic regulation of leukemia.
Chem Sci, 8, 2017
5M89
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Spliceosome component
分子名称: Spliceosome WD40 Sc
著者Moura, T.R, Pena, V.
登録日2016-10-28
公開日2018-03-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.605 Å)
主引用文献Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors.
Mol. Cell, 69, 2018
1NR0
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BU of 1nr0 by Molmil
Two Seven-Bladed Beta-Propeller Domains Revealed By The Structure Of A C. elegans Homologue Of Yeast Actin Interacting Protein 1 (AIP1).
分子名称: Actin interacting protein 1, MANGANESE (II) ION
著者Vorobiev, S.M, Mohri, K, Ono, S, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2003-01-23
公開日2003-07-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Identification of Functional Residues on Caenorhabditis elegans Actin-interacting Protein 1 (UNC-78) for Disassembly of Actin Depolymerizing Factor/Cofilin-bound Actin Filaments
J.Biol.Chem., 279, 2004
1PEV
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BU of 1pev by Molmil
Crystal Structure of the Actin Interacting Protein from Caenorhabditis Elegans
分子名称: Actin interacting protein 1
著者Vorobiev, S, Mohri, K, Fedorov, A.A, Ono, S, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2003-05-22
公開日2003-07-01
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification of functional residues on Caenorhabditis elegans actin-interacting protein 1 (UNC-78) for disassembly of actin depolymerizing factor/cofilin-bound actin filaments.
J.Biol.Chem., 279, 2004
1PGU
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BU of 1pgu by Molmil
YEAST ACTIN INTERACTING PROTEIN 1 (AIP1), Se-Met PROTEIN, MONOCLINIC CRYSTAL FORM
分子名称: Actin interacting protein 1, ZINC ION
著者Voegtli, W.C, Madrona, A.Y, Wilson, D.K.
登録日2003-05-28
公開日2003-07-15
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of Aip1p, a WD repeat protein that regulates Cofilin-mediated actin depolymerization.
J.Biol.Chem., 278, 2003
1PI6
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BU of 1pi6 by Molmil
YEAST ACTIN INTERACTING PROTEIN 1 (Aip1), ORTHORHOMBIC CRYSTAL FORM
分子名称: Actin interacting protein 1, ZINC ION
著者Voegtli, W.C, Madrona, A.Y, Wilson, D.K.
登録日2003-05-29
公開日2003-07-15
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of Aip1p, a WD repeat protein that regulates Cofilin-mediated actin depolymerization.
J.Biol.Chem., 278, 2003
5SXM
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BU of 5sxm by Molmil
WDR5 in complex with MLL Win motif peptidomimetic
分子名称: ACE-ALA-ARG-THR-GLU-VAL-TYR-NH2, WD repeat-containing protein 5
著者Alicea-Velazquez, N.L, Shinsky, S.A, Cosgrove, M.S.
登録日2016-08-09
公開日2016-09-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.
J.Biol.Chem., 291, 2016
1U4C
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BU of 1u4c by Molmil
Structure of spindle checkpoint protein Bub3
分子名称: Cell cycle arrest protein BUB3
著者Larsen, N.A, Harrison, S.C.
登録日2004-07-23
公開日2004-08-03
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of the spindle assembly checkpoint protein Bub3
J.Mol.Biol., 344, 2004
1TRJ
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BU of 1trj by Molmil
Homology Model of Yeast RACK1 Protein fitted into 11.7A cryo-EM map of Yeast 80S Ribosome
分子名称: Guanine nucleotide-binding protein beta subunit-like protein, Helix 39 of 18S rRNA, Helix 40 of 18S rRNA
著者Sengupta, J, Nilsson, J, Gursky, R, Spahn, C.M, Nissen, P, Frank, J.
登録日2004-06-21
公開日2004-09-28
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (11.7 Å)
主引用文献Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM
Nat.Struct.Mol.Biol., 11, 2004
1R5M
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BU of 1r5m by Molmil
Crystal Structure Of The C-Terminal WD40 Domain Of Sif2
分子名称: SIR4-interacting protein SIF2, SULFATE ION
著者Cerna, D, Wilson, D.K.
登録日2003-10-10
公開日2005-03-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The structure of Sif2p, a WD repeat protein functioning in the SET3 corepressor complex.
J.Mol.Biol., 351, 2005
1S4U
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Crystal Structure analysis of the beta-propeller protein Ski8p
分子名称: Antiviral protein SKI8
著者Cheng, Z, Song, H.
登録日2004-01-18
公開日2004-12-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Ski8p, a WD-repeat protein with dual roles in mRNA metabolism and meiotic recombination
Protein Sci., 13, 2004

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