2CO0

WDR5 and unmodified Histone H3 complex at 2.25 Angstrom

Summary for 2CO0

Entry DOI	10.2210/pdb2co0/pdb
Related	2CNX 2GNQ
Descriptor	WD-REPEAT PROTEIN 5, HISTONE H3 DIMETHYL-LYSINE 4, ... (4 entities in total)
Functional Keywords	transcription, histone presenter, lysine methylation, mll1, leukemia, hox gene activation, transcription activation
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Nucleus : P61964 P61964 Chromosome : Q5TEC6
Total number of polymer chains	4
Total formula weight	72320.02
Authors	Ruthenburg, A.J.,Wang, W.,Graybosch, D.M.,Li, H.,Allis, C.D.,Patel, D.J.,Verdine, G.L. (deposition date: 2006-05-25, release date: 2006-07-03, Last modification date: 2023-12-13)
Primary citation	Ruthenburg, A.J.,Wang, W.,Graybosch, D.M.,Li, H.,Allis, C.D.,Patel, D.J.,Verdine, G.L. Histone H3 Recognition and Presentation by the Wdr5 Module of the Mll1 Complex Nat.Struct.Mol.Biol., 13:704-, 2006 Cited by PubMed: 16829959 DOI: 10.1038/NSMB1119 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation