2CNX
WDR5 and Histone H3 Lysine 4 dimethyl complex at 2.1 angstrom
Summary for 2CNX
Entry DOI | 10.2210/pdb2cnx/pdb |
Related | 2CO0 2GNQ |
Descriptor | WD-REPEAT PROTEIN 5, HISTONE H3 DIMETHYL-LYSINE 4 (3 entities in total) |
Functional Keywords | histone presenter, lysine methylation, mll1, leukemia, hox gene activation, transcription activation, transcription |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus : P61964 Chromosome . Nucleus : Q5TEC6 |
Total number of polymer chains | 2 |
Total formula weight | 35218.96 |
Authors | Ruthenburg, A.J.,Wang, W.,Graybosch, D.M.,Li, H.,Allis, C.D.,Patel, D.J.,Verdine, G.L. (deposition date: 2006-05-25, release date: 2006-07-03, Last modification date: 2023-12-13) |
Primary citation | Ruthenburg, A.J.,Wang, W.,Graybosch, D.M.,Li, H.,Allis, C.D.,Patel, D.J.,Verdine, G.L. Histone H3 Recognition and Presentation by the Wdr5 Module of the Mll1 Complex Nat.Struct.Mol.Biol., 13:704-, 2006 Cited by PubMed: 16829959DOI: 10.1038/NSMB1119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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