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3MEV
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BU of 3mev by Molmil
Crystal structure of SGF29 in complex with R2AK4me3
分子名称: GLYCEROL, Histone H3, SAGA-associated factor 29 homolog, ...
著者Bian, C.B, Xu, C, Lam, R, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2021-10-06
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MEU
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BU of 3meu by Molmil
Crystal structure of SGF29 in complex with H3R2me2sK4me3
分子名称: Histone H3, SAGA-associated factor 29 homolog, SULFATE ION
著者Bian, C.B, Xu, C, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MEW
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BU of 3mew by Molmil
Crystal structure of Novel Tudor domain-containing protein SGF29
分子名称: SAGA-associated factor 29 homolog
著者Xu, C, Bian, C.B, Lam, R, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MET
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BU of 3met by Molmil
Crystal structure of SGF29 in complex with H3K4me2
分子名称: GLYCEROL, Histone H3, SAGA-associated factor 29 homolog, ...
著者Bian, C.B, Xu, C, Lam, R, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2011-08-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
5JSJ
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BU of 5jsj by Molmil
Crystal structure of Spindlin1 bound to compound EML631
分子名称: CHLORIDE ION, MAGNESIUM ION, Spindlin-1, ...
著者Su, X, Li, H.
登録日2016-05-08
公開日2017-05-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.348 Å)
主引用文献Developing Spindlin1 small-molecule inhibitors by using protein microarrays
Nat. Chem. Biol., 13, 2017
5JSG
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BU of 5jsg by Molmil
Crystal structure of Spindlin1 bound to compound EML405
分子名称: CHLORIDE ION, MAGNESIUM ION, Spindlin-1, ...
著者Su, X, Li, H.
登録日2016-05-08
公開日2017-05-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Developing Spindlin1 small-molecule inhibitors by using protein microarrays
Nat. Chem. Biol., 13, 2017
5Y5W
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BU of 5y5w by Molmil
Crystal structure of human Spindlin1 in complex with a histone H4K20(me3) peptide
分子名称: Histone peptide H4K20(me3), Spindlin-1
著者Wang, C, Zang, J.
登録日2017-08-10
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Spindlin-1 recognizes methylations of K20 and R23 of histone H4 tail
FEBS Lett., 592, 2018
5Y20
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BU of 5y20 by Molmil
Crystal structure of AL1 PHD finger bound to H3K4me3
分子名称: PEPTIDE FROM HISTONE H3, PHD finger protein ALFIN-LIKE 1, ZINC ION
著者Zhao, S, Zhang, B, Li, H.
登録日2017-07-22
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.409 Å)
主引用文献Systematic Profiling of Histone Readers in Arabidopsis thaliana.
Cell Rep, 22, 2018
3MP8
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BU of 3mp8 by Molmil
Crystal structure of Sgf29 tudor domain
分子名称: 4-(HYDROXYMETHYL)BENZAMIDINE, ACETIC ACID, GLYCEROL, ...
著者Li, J, Wu, M, Ruan, J, Zang, J.
登録日2010-04-26
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
7M10
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BU of 7m10 by Molmil
PHF2 PHD Domain Complexed with Peptide From N-terminus of VRK1
分子名称: FORMIC ACID, Lysine-specific demethylase PHF2, Serine/threonine-protein kinase VRK1 N-terminus peptide, ...
著者Horton, J.R, Cheng, X.
登録日2021-03-11
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions.
Biochem.J., 478, 2021
3GL6
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BU of 3gl6 by Molmil
Crystal structure of JARID1A-PHD3 complexed with H3(1-9)K4me3 peptide
分子名称: Histone H3, Histone demethylase JARID1A, ZINC ION
著者Wang, Z, Song, J, Patel, D.J.
登録日2009-03-11
公開日2009-05-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
2KGI
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BU of 2kgi by Molmil
Solution structure of JARID1A C-terminal PHD finger in complex with H3(1-9)K4me3
分子名称: H3(1-9)K4me3, Histone demethylase JARID1A, ZINC ION
著者Song, J, Wang, Z, Patel, D.J.
登録日2009-03-12
公開日2009-05-05
最終更新日2020-02-26
実験手法SOLUTION NMR
主引用文献Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
6WXK
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BU of 6wxk by Molmil
PHF23 PHD Domain Apo
分子名称: PHD finger protein 23, ZINC ION
著者Vann, K.R, Zhang, J, Zhang, Y, Kutateladze, T.
登録日2020-05-11
公開日2020-07-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion.
Nat Commun, 11, 2020
4PLI
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BU of 4pli by Molmil
Structure of the chromodomain of MRG2 in complex with H3K36me3
分子名称: At1g02740, H3K36me3
著者Liu, Y, Huang, Y.
登録日2014-05-18
公開日2015-07-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.651 Å)
主引用文献Regulation of arabidopsis flowering by the histone mark readers MRG1/2 via interaction with CONSTANS to modulate FT expression.
Plos Genet., 10, 2014
4PLL
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BU of 4pll by Molmil
Structure of the chromodaomain of MRG2 in complex with H3K36me3
分子名称: At1g02740, H3K36me3
著者Liu, Y, Huang, Y.
登録日2014-05-18
公開日2015-07-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Regulation of arabidopsis flowering by the histone mark readers MRG1/2 via interaction with CONSTANS to modulate FT expression.
Plos Genet., 10, 2014
7BU9
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BU of 7bu9 by Molmil
Crystal Structure of Spindlin1-H3(K4me3-K9me2) complex
分子名称: H3(K4me3-K9me2) peptide, Spindlin-1
著者Zhao, F, Li, H.
登録日2020-04-05
公開日2020-10-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.502 Å)
主引用文献Molecular basis for histone H3 "K4me3-K9me3/2" methylation pattern readout by Spindlin1.
J.Biol.Chem., 295, 2020
7BQZ
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BU of 7bqz by Molmil
Crystal Structure of Spindlin1 bound to H3(K4me3-K9me3) peptide
分子名称: H3(K4me3-K9me3) peptide, Spindlin-1
著者Zhao, F, Li, H.
登録日2020-03-26
公開日2020-10-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Molecular basis for histone H3 "K4me3-K9me3/2" methylation pattern readout by Spindlin1.
J.Biol.Chem., 295, 2020
8COK
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BU of 8cok by Molmil
Structural analysis of ING3 protein and its binding to histone H3
分子名称: Inhibitor of growth protein 3
著者Ferreras-Gutierrez, M, Medrano, F.J, Blanco, F.J.
登録日2023-02-28
公開日2023-05-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Structural analysis of ING3 protein and histone H3 binding.
Int.J.Biol.Macromol., 242, 2023
2YBA
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BU of 2yba by Molmil
Crystal structure of Nurf55 in complex with histone H3
分子名称: HISTONE H3, PROBABLE HISTONE-BINDING PROTEIN CAF1
著者Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H.
登録日2011-03-02
公開日2011-05-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks
Mol.Cell, 42, 2011
2YB8
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BU of 2yb8 by Molmil
Crystal structure of Nurf55 in complex with Su(z)12
分子名称: POLYCOMB PROTEIN SU(Z)12, PROBABLE HISTONE-BINDING PROTEIN CAF1, SULFATE ION
著者Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H.
登録日2011-03-02
公開日2011-05-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks.
Mol.Cell, 42, 2011
2KGG
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BU of 2kgg by Molmil
Solution Structure of JARID1A C-terminal PHD finger
分子名称: Histone demethylase JARID1A, ZINC ION
著者Song, J, Wang, Z, Patel, D.J.
登録日2009-03-11
公開日2009-05-05
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
2KYX
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BU of 2kyx by Molmil
Solution structure of the RRM domain of CYP33
分子名称: Peptidyl-prolyl cis-trans isomerase E
著者Park, S, Bushweller, J.H.
登録日2010-06-09
公開日2010-08-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression .
Biochemistry, 49, 2010
2KU7
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BU of 2ku7 by Molmil
Solution structure of MLL1 PHD3-Cyp33 RRM chimeric protein
分子名称: MLL1 PHD3-Cyp33 RRM chimeric protein
著者Song, J, Wang, Z, Patel, D.
登録日2010-02-12
公開日2010-07-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell(Cambridge,Mass.), 141, 2010
2KYU
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BU of 2kyu by Molmil
The solution structure of the PHD3 finger of MLL
分子名称: Histone-lysine N-methyltransferase MLL, ZINC ION
著者Park, S, Bushweller, J.H.
登録日2010-06-08
公開日2010-08-25
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression.
Biochemistry, 49, 2010
6W5N
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BU of 6w5n by Molmil
Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class05)
分子名称: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U.
登録日2020-03-13
公開日2021-03-31
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin.
Nat Commun, 12, 2021

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