8E1D
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6FGS
| Solution structure of p300Taz2-p73TA1 | Descriptor: | Histone acetyltransferase p300,Tumor protein p73, ZINC ION | Authors: | Gebel, J, Kazemi, S, Lohr, F, Guntert, P, Dotsch, V. | Deposit date: | 2018-01-11 | Release date: | 2018-05-30 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain. Structure, 26, 2018
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1P4Q
| Solution structure of the CITED2 transactivation domain in complex with the p300 CH1 domain | Descriptor: | Cbp/p300-interacting transactivator 2, E1A-associated protein p300, ZINC ION | Authors: | Freedman, S.J, Sun, Z.-Y.J, Kung, A.L, France, D.S, Wagner, G, Eck, M.J. | Deposit date: | 2003-04-23 | Release date: | 2003-07-01 | Last modified: | 2017-02-01 | Method: | SOLUTION NMR | Cite: | Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2. Nat.Struct.Biol., 10, 2003
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3IO2
| Crystal structure of the Taz2 domain of p300 | Descriptor: | Histone acetyltransferase p300, SULFATE ION, ZINC ION | Authors: | Miller, M, Dauter, Z, Wlodawer, A. | Deposit date: | 2009-08-13 | Release date: | 2009-11-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the Taz2 domain of p300: insights into ligand binding. Acta Crystallogr.,Sect.D, 65, 2009
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1F81
| SOLUTION STRUCTURE OF THE TAZ2 DOMAIN OF THE TRANSCRIPTIONAL ADAPTOR PROTEIN CBP | Descriptor: | CREB-BINDING PROTEIN, ZINC ION | Authors: | De Guzman, R.N, Liu, H.L, Martinez-Yamout, M, Dyson, H.J, Wright, P.E. | Deposit date: | 2000-06-28 | Release date: | 2000-10-18 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP. J.Mol.Biol., 303, 2000
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6FGN
| Solution Structure of p300Taz2-p63TA | Descriptor: | Histone acetyltransferase p300,Tumor protein 63, ZINC ION | Authors: | Gebel, J, Kazemi, S, Lohr, F, Guntert, P, Dotsch, V. | Deposit date: | 2018-01-11 | Release date: | 2018-05-30 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain. Structure, 26, 2018
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3T92
| Crystal structure of the Taz2:C/EBPepsilon-TAD chimera protein | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, ACETONE, HISTONE ACETYLTRANSFERASE P300 TAZ2-CCAAT/ENHANCER-BINDING PROTEIN EPSILON, ... | Authors: | Bhaumik, P, Maria, M. | Deposit date: | 2011-08-02 | Release date: | 2012-08-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural insights into interactions of C/EBP transcriptional activators with the Taz2 domain of p300. Acta Crystallogr. D Biol. Crystallogr., 70, 2014
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2KJE
| NMR structure of CBP TAZ2 and adenoviral E1A complex | Descriptor: | CREB-binding protein, Early E1A 32 kDa protein, ZINC ION | Authors: | Ferreon, J.C, Martinez-Yamout, M, Dyson, H, Wright, P.E. | Deposit date: | 2009-05-27 | Release date: | 2009-09-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein. Proc.Natl.Acad.Sci.USA, 106, 2009
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1U2N
| Structure CBP TAZ1 Domain | Descriptor: | CREB binding protein, ZINC ION | Authors: | De Guzman, R.N, Wojciak, J.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | Deposit date: | 2004-07-19 | Release date: | 2005-04-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding Biochemistry, 44, 2005
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1R8U
| NMR structure of CBP TAZ1/CITED2 complex | Descriptor: | CREB-binding protein, Cbp/p300-interacting transactivator 2, ZINC ION | Authors: | De Guzman, R.N, Martinez-Yamout, M, Dyson, H.J, Wright, P.E. | Deposit date: | 2003-10-28 | Release date: | 2004-03-23 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites. J.Biol.Chem., 279, 2004
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7XEZ
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7XFG
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2LWW
| NMR structure of RelA-TAD/CBP-TAZ1 complex | Descriptor: | CREB-binding protein, Nuclear transcription factor RelA, ZINC ION | Authors: | Mukherjee, S.P, Ghosh, G, Wright, P.E. | Deposit date: | 2012-08-07 | Release date: | 2013-09-11 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-kappa B-Driven Transcription. Plos Biol., 11, 2013
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2MH0
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1LIQ
| Non-native Solution Structure of a fragment of the CH1 domain of CBP | Descriptor: | CREB Binding Protein, ZINC ION | Authors: | Sharpe, B.K, Matthews, J.M, Kwan, A.H.Y, Newton, A, Gell, D.A, Crossley, M, Mackay, J.P. | Deposit date: | 2002-04-18 | Release date: | 2002-05-29 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | A New Zinc Binding Fold Underlines the Versatility of Zinc Binding Modules in Protein Evolution Structure, 10, 2002
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1WO3
| Solution structure of Minimal Mutant 1 (MM1): Multiple alanine mutant of non-native CHANCE domain | Descriptor: | CREB Binding Protein, ZINC ION | Authors: | Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P. | Deposit date: | 2004-08-12 | Release date: | 2005-03-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting Structure, 13, 2005
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1WO6
| Solution structure of Designed Functional Finger 5 (DFF5): Designed mutant based on non-native CHANCE domain | Descriptor: | CREB Binding Protein, ZINC ION | Authors: | Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P. | Deposit date: | 2004-08-12 | Release date: | 2005-03-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting Structure, 13, 2005
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1WO4
| Solution structure of Minimal Mutant 2 (MM2): Multiple alanine mutant of non-native CHANCE domain | Descriptor: | CREB Binding Protein, ZINC ION | Authors: | Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P. | Deposit date: | 2004-08-12 | Release date: | 2005-03-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting Structure, 13, 2005
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1WO5
| Solution structure of Designed Functional Finger 2 (DFF2): Designed mutant based on non-native CHANCE domain | Descriptor: | CREB Binding Protein, ZINC ION | Authors: | Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P. | Deposit date: | 2004-08-12 | Release date: | 2005-03-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting Structure, 13, 2005
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1WO7
| Solution structure of Designed Functional Finger 7 (DFF7): Designed mutant based on non-native CHANCE domain | Descriptor: | CREB Binding Protein, ZINC ION | Authors: | Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P. | Deposit date: | 2004-08-12 | Release date: | 2005-03-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting Structure, 13, 2005
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7QGS
| Crystal structure of p300 CH1 domain in complex with CITIF (a CITED2-HIF-1alpha hybrid) | Descriptor: | Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha, Histone acetyltransferase, ZINC ION | Authors: | Hegedus, Z, Wilson, A.J, Edwards, T.A. | Deposit date: | 2021-12-10 | Release date: | 2022-05-11 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Understanding p300-transcription factor interactions using sequence variation and hybridization. Rsc Chem Biol, 3, 2022
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7LVS
| The CBP TAZ1 Domain in Complex with a CITED2-HIF-1-Alpha Fusion Peptide | Descriptor: | Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha, Histone lysine acetyltransferase CREBBP, ZINC ION | Authors: | Appling, F.D, Berlow, R.B, Stanfield, R.L, Dyson, H.J, Wright, P.E. | Deposit date: | 2021-02-26 | Release date: | 2021-07-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | The molecular basis of allostery in a facilitated dissociation process. Structure, 29, 2021
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2K8F
| Structural Basis for the Regulation of p53 Function by p300 | Descriptor: | Cellular tumor antigen p53, Histone acetyltransferase p300 | Authors: | Bai, Y, Feng, H, Jenkins, L.M, Durell, S.R, Wiodawer, A, Appella, E. | Deposit date: | 2008-09-08 | Release date: | 2009-03-03 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation. Structure, 17, 2009
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2KA4
| NMR structure of the CBP-TAZ1/STAT2-TAD complex | Descriptor: | Crebbp protein, Signal transducer and activator of transcription 2, ZINC ION | Authors: | Wojciak, J.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | Deposit date: | 2008-10-30 | Release date: | 2009-04-21 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains Embo J., 28, 2009
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2KA6
| NMR structure of the CBP-TAZ2/STAT1-TAD complex | Descriptor: | CREB-binding protein, Signal transducer and activator of transcription 1-alpha/beta, ZINC ION | Authors: | Wojciak, J.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | Deposit date: | 2008-10-30 | Release date: | 2009-04-07 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains. Embo J., 28, 2009
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