NMR structure of CBP TAZ2 and adenoviral E1A complex

Summary for 2KJE

DescriptorCREB-binding protein, Early E1A 32 kDa protein, ZINC ION (3 entities in total)
Functional Keywordscbp, taz2, e1a, adenoviral, acetylation, activator, bromodomain, chromosomal rearrangement, disease mutation, host-virus interaction, isopeptide bond, metal-binding, methylation, nucleus, phosphoprotein, transcription, transcription regulation, transferase, ubl conjugation, zinc, zinc-finger, alternative splicing, dna-binding, early protein, oncogene
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q92793
Host nucleus (Potential) P03255
Total number of polymer chains2
Total molecular weight15188.7
Ferreon, J.C.,Martinez-Yamout, M.,Dyson, H.,Wright, P.E. (deposition date: 2009-05-27, release date: 2009-09-15, Last modification date: 2011-07-13)
Primary citation
Ferreon, J.C.,Martinez-Yamout, M.A.,Dyson, H.J.,Wright, P.E.
Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein.
Proc.Natl.Acad.Sci.USA, 106:13260-13265, 2009
PubMed: 19651603 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.0906770106
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers00.7%3.7%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures