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3ZID
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BU of 3zid by Molmil
CetZ from Methanosaeta thermophila strain DSM 6194
Descriptor: GUANOSINE-5'-DIPHOSPHATE, TUBULIN/FTSZ, GTPASE
Authors:Aylett, C.H.S, Amos, L.A, Lowe, J.
Deposit date:2013-01-08
Release date:2013-08-14
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cetz Tubulin-Like Proteins Control Archaeal Cell Shape
Nature, 519, 2015
9F8G
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BU of 9f8g by Molmil
Photostatin (photoswitchable azo-combretastatin) Z-PST27 bound to tubulin-DARPin D1 complex
Descriptor: 5-[(~{Z})-(3,5-diethyl-4-methoxy-phenyl)diazenyl]-2-methyl-phenol, CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ...
Authors:Wranik, M, Steinmetz, M.O.
Deposit date:2024-05-06
Release date:2024-09-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A photo-SAR study of photoswitchable azobenzene tubulin-inhibiting antimitotics identifying a general method for near-quantitative photocontrol.
Chem Sci, 15, 2024
4UXT
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BU of 4uxt by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN HEAVY CHAIN ISOFORM 5A, ...
Authors:Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
Deposit date:2014-08-27
Release date:2014-09-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
5FNV
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BU of 5fnv by Molmil
a new complex structure of tubulin with an alpha-beta unsaturated lactone
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Wang, Y, Naismith, J, Zhu, X.
Deposit date:2015-11-16
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Pironetin Reacts Covalently with Cysteine-316 of Alpha-Tubulin to Destabilize Microtubule.
Nat.Commun., 7, 2016
6PC4
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BU of 6pc4 by Molmil
Tubulin-RB3_SLD-TTL in complex with compound ABI-274
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Kumar, G, Wang, Y, Li, W, White, S.W.
Deposit date:2019-06-15
Release date:2020-04-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.602 Å)
Cite:Structure-Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties.
J.Med.Chem., 63, 2020
1OFU
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BU of 1ofu by Molmil
Crystal structure of SulA:FtsZ from Pseudomonas aeruginosa
Descriptor: CELL DIVISION PROTEIN FTSZ, GUANOSINE-5'-DIPHOSPHATE, HYPOTHETICAL PROTEIN PA3008
Authors:Cordell, S.C, Robinson, E.J.H, Lowe, J.
Deposit date:2003-04-21
Release date:2003-06-19
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the SOS Cell Division Inhibitor Sula and in Complex with Ftsz
Proc.Natl.Acad.Sci.USA, 100, 2003
6VPP
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BU of 6vpp by Molmil
Cryo-EM structure of microtubule-bound KLP61F motor with tail domain in the nucleotide-free state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp61F, ...
Authors:Bodrug, T, Wilson-Kubalek, E.M, Nithianantham, S, Debs, G, Sindelar, C.V, Milligan, R, Al-Bassam, J.
Deposit date:2020-02-04
Release date:2020-02-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
Elife, 9, 2020
6I5C
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BU of 6i5c by Molmil
Long wavelength native-SAD phasing of Tubulin-Stathmin-TTL complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Basu, S, Olieric, V, Matsugaki, N, Kawano, Y, Takashi, T, Huang, C.Y, Leonarski, F, Yamada, Y, Vera, L, Olieric, N, Basquin, J, Wojdyla, J.A, Diederichs, K, Yamamoto, M, Bunk, O, Wang, M.
Deposit date:2018-11-13
Release date:2019-03-13
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-wavelength native-SAD phasing: opportunities and challenges.
Iucrj, 6, 2019
8C0F
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BU of 8c0f by Molmil
Tubulin-PTC596 complex
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-fluoranyl-2-(6-fluoranyl-2-methyl-benzimidazol-1-yl)-~{N}4-[4-(trifluoromethyl)phenyl]pyrimidine-4,6-diamine, ...
Authors:Prota, A.E, Muehlethaler, T, Weetall, M, Steinmetz, M.O.
Deposit date:2022-12-16
Release date:2022-12-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1005 Å)
Cite:Preclinical and Early Clinical Development of PTC596, a Novel Small-Molecule Tubulin-Binding Agent
Mol Cancer Ther, 20, 2021
8C5C
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BU of 8c5c by Molmil
microtubule decorated with tubulin oligomers in presence of APC C-terminal domain. (here only map corresponding to the 13-pf microtubule is represented)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Serre, L, Arnal, I.
Deposit date:2023-01-06
Release date:2023-01-25
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:The mitotic role of adenomatous polyposis coli requires its bilateral interaction with tubulin and microtubules.
J.Cell.Sci., 136, 2023
6VPO
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BU of 6vpo by Molmil
Cryo-EM structure of microtubule-bound KLP61F motor domain in the AMPPNP state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp61F, ...
Authors:Bodrug, T, Wilson-Kubalek, E.M, Nithianantham, S, Debs, G, Sindelar, C.V, Milligan, R, Al-Bassam, J.
Deposit date:2020-02-04
Release date:2020-02-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
Elife, 9, 2020
6I2I
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BU of 6i2i by Molmil
Refined 13pf Hela Cell Tubulin microtubule (EML4-NTD decorated)
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Atherton, J.M, Moores, C.A.
Deposit date:2018-11-01
Release date:2019-08-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression.
Sci.Signal., 12, 2019
3RYI
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BU of 3ryi by Molmil
GDP-Tubulin: rb3 stathmin-like domain complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Nawrotek, A, Knossow, M, Gigant, B.
Deposit date:2011-05-11
Release date:2011-10-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin.
J.Mol.Biol., 412, 2011
3RYC
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BU of 3ryc by Molmil
Tubulin: RB3 stathmin-like domain complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Nawrotek, A, Knossow, M, Gigant, B.
Deposit date:2011-05-11
Release date:2011-10-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin.
J.Mol.Biol., 412, 2011
2HXF
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BU of 2hxf by Molmil
KIF1A head-microtubule complex structure in amppnp-form
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ...
Authors:Kikkawa, M, Hirokawa, N.
Deposit date:2006-08-03
Release date:2006-10-10
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (10 Å)
Cite:High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations
Embo J., 25, 2006
1JFF
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BU of 1jff by Molmil
Refined structure of alpha-beta tubulin from zinc-induced sheets stabilized with taxol
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Lowe, J, Li, H, Downing, K.H, Nogales, E.
Deposit date:2001-06-20
Release date:2001-09-19
Last modified:2023-08-16
Method:ELECTRON CRYSTALLOGRAPHY (3.5 Å)
Cite:Refined structure of alpha beta-tubulin at 3.5 A resolution.
J.Mol.Biol., 313, 2001
1IA0
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BU of 1ia0 by Molmil
KIF1A HEAD-MICROTUBULE COMPLEX STRUCTURE IN ATP-FORM
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF1A, ...
Authors:Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N.
Deposit date:2001-03-22
Release date:2002-03-22
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Switch-based Mechanism of Kinesin Motors
Nature, 411, 2001
2BTQ
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BU of 2btq by Molmil
Structure of BtubAB heterodimer from Prosthecobacter dejongeii
Descriptor: GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, TUBULIN BTUBA, ...
Authors:Schlieper, D, Lowe, J.
Deposit date:2005-06-06
Release date:2005-06-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of Bacterial Tubulin Btuba/B: Evidence for Horizontal Gene Transfer.
Proc.Natl.Acad.Sci.USA, 102, 2005
2XRP
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BU of 2xrp by Molmil
Human Doublecortin N-DC Repeat (1MJD) and Mammalian Tubulin (1JFF and 3HKE) Docked into the 8-Angstrom Cryo-EM Map of Doublecortin- Stabilised Microtubules
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, NEURONAL MIGRATION PROTEIN DOUBLECORTIN, ...
Authors:Fourniol, F.J, Sindelar, C.V, Amigues, B, Clare, D.K, Thomas, G, Perderiset, M, Francis, F, Houdusse, A, Moores, C.A.
Deposit date:2010-09-18
Release date:2010-11-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:Template-Free 13-Protofilament Microtubule-Map Assembly Visualized at 8 A Resolution.
J.Cell Biol., 191, 2010
3N2K
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BU of 3n2k by Molmil
TUBULIN-NSC 613862: RB3 Stathmin-like domain complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M.
Deposit date:2010-05-18
Release date:2010-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4 Å)
Cite:Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers.
J.Biol.Chem., 285, 2010
1FSZ
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BU of 1fsz by Molmil
CRYSTAL STRUCTURE OF THE CELL-DIVISION PROTEIN FTSZ AT 2.8A RESOLUTION
Descriptor: FTSZ, GUANOSINE-5'-DIPHOSPHATE
Authors:Lowe, J, Amos, L.A.
Deposit date:1997-06-24
Release date:1998-06-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the bacterial cell-division protein FtsZ.
Nature, 391, 1998
3N2G
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BU of 3n2g by Molmil
TUBULIN-NSC 613863: RB3 Stathmin-like domain complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M.
Deposit date:2010-05-18
Release date:2010-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4 Å)
Cite:Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers.
J.Biol.Chem., 285, 2010
2HXH
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BU of 2hxh by Molmil
KIF1A head-microtubule complex structure in adp-form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Kikkawa, M, Hirokawa, N.
Deposit date:2006-08-03
Release date:2006-10-10
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (11 Å)
Cite:High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations
Embo J., 25, 2006
1FFX
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BU of 1ffx by Molmil
TUBULIN:STATHMIN-LIKE DOMAIN COMPLEX
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, PROTEIN (STATHMIN-LIKE DOMAIN OF RB3), ...
Authors:Gigant, B, Martin-Barbey, C, Knossow, M.
Deposit date:2000-07-26
Release date:2000-09-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:The 4 A X-ray structure of a tubulin:stathmin-like domain complex.
Cell(Cambridge,Mass.), 102, 2000
3CB2
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BU of 3cb2 by Molmil
Crystal structure of human gamma-tubulin bound to GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, tubulin gamma-1 chain
Authors:Rice, L.M, Montabana, E.A, Agard, D.A.
Deposit date:2008-02-21
Release date:2008-06-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:The lattice as allosteric effector: structural studies of alphabeta- and gamma-tubulin clarify the role of GTP in microtubule assembly
Proc.Natl.Acad.Sci.Usa, 105, 2008

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