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PDB形式変換不可の PDB エントリー
6SRX
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BU of 6srx by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021158
分子名称: ACETATE ION, CHLORIDE ION, Fab C0021158 heavy chain (IgG1), ...
著者Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
登録日2019-09-06
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS0
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Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021181
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Fab C0021181 heavy chain (IgG1), ...
著者Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
登録日2019-09-06
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS2
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BU of 6ss2 by Molmil
Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0021158
分子名称: Arginase-2, mitochondrial, Fab C0021158 heavy chain (IgG1), ...
著者Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
登録日2019-09-06
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS4
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BU of 6ss4 by Molmil
Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0021181
分子名称: Arginase-2, mitochondrial, Fab C0021181 heavy chain (IgG1), ...
著者Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
登録日2019-09-06
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS5
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BU of 6ss5 by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0020187
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
登録日2019-09-06
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6SS6
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BU of 6ss6 by Molmil
Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0020187
分子名称: Arginase-2, mitochondrial, Fab C0020187 heavy chain (IgG1), ...
著者Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
登録日2019-09-06
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6SUE
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BU of 6sue by Molmil
Structure of Photorhabdus luminescens Tc holotoxin pore, Mutation TccC3-D651A
分子名称: TcdA1, TcdB2,TccC3
著者Roderer, D, Raunser, S.
登録日2019-09-13
公開日2019-11-06
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of a Tc holotoxin pore provides insights into the translocation mechanism.
Proc.Natl.Acad.Sci.USA, 116, 2019
6SUF
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BU of 6suf by Molmil
Structure of Photorhabdus luminescens Tc holotoxin pore
分子名称: TcdA1, TcdB2,TccC3
著者Roderer, D, Raunser, S.
登録日2019-09-13
公開日2019-11-06
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of a Tc holotoxin pore provides insights into the translocation mechanism.
Proc.Natl.Acad.Sci.USA, 116, 2019
6SUJ
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BU of 6suj by Molmil
Mutations in SsgB correlate to longitudinal cell division during sporulation of Streptomyces coelicolor
分子名称: PHOSPHATE ION, Sporulation and cell division protein SsgA
著者Xiao, X.S, Willemse, J.
登録日2019-09-14
公開日2020-09-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Mutations in SsgB correlate to longitudinal cell division during sporulation of Streptomyces coelicolor
To Be Published
6SUV
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BU of 6suv by Molmil
Horse cytochrome c complexed by octa-anionic calixarene
分子名称: ACETYL GROUP, Cytochrome c, HEME C, ...
著者Geremia, S, Brancatelli, G.
登録日2019-09-16
公開日2020-07-22
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Probing the determinants of porosity in protein frameworks: co-crystals of cytochrome c and an octa-anionic calix[4]arene
Org.Biomol.Chem., 18, 2020
6SV4
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BU of 6sv4 by Molmil
The cryo-EM structure of SDD1-stalled collided trisome.
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Tesina, P, Buschauer, R, Cheng, J, Becker, T, Beckmann, R.
登録日2019-09-17
公開日2020-03-04
最終更新日2020-04-22
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1.
Nat.Struct.Mol.Biol., 27, 2020
6SWA
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BU of 6swa by Molmil
Mus musculus brain neocortex ribosome 60S bound to Ebp1
分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Kraushar, M.L, Sprink, T.
登録日2019-09-20
公開日2020-09-30
最終更新日2021-02-17
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit.
Mol.Cell, 81, 2021
6SWN
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BU of 6swn by Molmil
N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH iBET-BD1 (GSK778)
分子名称: 1,2-ETHANEDIOL, 4-[2-(methoxymethyl)-1-[(1~{R})-1-phenylethyl]-8-[[(3~{S})-pyrrolidin-3-yl]methoxy]imidazo[4,5-c]quinolin-7-yl]-3,5-dimethyl-1,2-oxazole, Bromodomain-containing protein 4, ...
著者Chung, C.
登録日2019-09-22
公開日2020-04-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.
Science, 368, 2020
6SWO
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BU of 6swo by Molmil
C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH iBET-BD1 (GSK778)
分子名称: 1,2-ETHANEDIOL, 4-[2-(methoxymethyl)-1-[(1~{R})-1-phenylethyl]-8-[[(3~{S})-pyrrolidin-3-yl]methoxy]imidazo[4,5-c]quinolin-7-yl]-3,5-dimethyl-1,2-oxazole, Bromodomain-containing protein 2
著者Chung, C.
登録日2019-09-22
公開日2020-04-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.
Science, 368, 2020
6SWP
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BU of 6swp by Molmil
C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH iBET-BD2 (GSK046)
分子名称: 1,2-ETHANEDIOL, 4-acetamido-3-fluoranyl-~{N}-(4-oxidanylcyclohexyl)-5-[(1~{S})-1-phenylethoxy]benzamide, Bromodomain-containing protein 2
著者Chung, C.
登録日2019-09-22
公開日2020-04-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.604 Å)
主引用文献Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.
Science, 368, 2020
6SWQ
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BU of 6swq by Molmil
N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH iBET-BD2 (GSK046)
分子名称: 1,2-ETHANEDIOL, 4-acetamido-3-fluoranyl-~{N}-(4-oxidanylcyclohexyl)-5-[(1~{S})-1-phenylethoxy]benzamide, Bromodomain-containing protein 4
著者Chung, C.
登録日2019-09-22
公開日2020-04-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.
Science, 368, 2020
6SWV
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BU of 6swv by Molmil
Trypsin fast data collection
分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ...
著者von Stetten, D, Mueller-Dieckmann, C.
登録日2019-09-24
公開日2020-05-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.432 Å)
主引用文献ID30A-3 (MASSIF-3) - a beamline for macromolecular crystallography at the ESRF with a small intense beam.
J.Synchrotron Radiat., 27, 2020
6SWZ
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BU of 6swz by Molmil
Structure of the C-terminal domain of C. glutamicum mycoloyltransferase A
分子名称: GLYCEROL, Protein PS1
著者Li de la Sierra-Gallay, I, Van tilbeurgh, H, Bayan, N.
登録日2019-09-24
公開日2020-03-04
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.995 Å)
主引用文献The C-terminal domain of Corynebacterium glutamicum mycoloyltransferase A is composed of five repeated motifs involved in cell wall binding and stability.
Mol.Microbiol., 114, 2020
6SX4
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BU of 6sx4 by Molmil
Structure of C. glutamicum mycoloyltransferase A
分子名称: ACETATE ION, Protein PS1
著者Li de la Sierra-Gallay, I, Van tilbeurgh, H, Bayan, N.
登録日2019-09-24
公開日2020-03-04
最終更新日2020-07-22
実験手法X-RAY DIFFRACTION (2.796 Å)
主引用文献The C-terminal domain of Corynebacterium glutamicum mycoloyltransferase A is composed of five repeated motifs involved in cell wall binding and stability.
Mol.Microbiol., 114, 2020
6SXO
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BU of 6sxo by Molmil
Cryo-EM structure of the human Ebp1-ribosome complex
分子名称: 28S ribosomal RNA including ES27L-B (2839-3265), 5.8S ribosomal RNA, 60S ribosomal protein L19, ...
著者Wild, K, Aleksic, M, Pfeffer, M, Sinning, I.
登録日2019-09-26
公開日2020-02-19
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments.
Nat Commun, 11, 2020
6SXS
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BU of 6sxs by Molmil
GH54 a-l-arabinofuranosidase soaked with cyclic sulfate inhibitor
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者McGregor, N.G.S, Davies, G.J, Nin-Hill, A, Rovira, C.
登録日2019-09-26
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.859 Å)
主引用文献Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining alpha-l-Arabinofuranosidases.
J.Am.Chem.Soc., 142, 2020
6SXU
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BU of 6sxu by Molmil
GH51 a-l-arabinofuranosidase soaked with cyclic sulfate inhibitor
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者McGregor, N.G.S, Davies, G.J.
登録日2019-09-26
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.398 Å)
主引用文献Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining alpha-l-Arabinofuranosidases.
J.Am.Chem.Soc., 142, 2020
6SYO
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BU of 6syo by Molmil
Hydrogenase-2 variant R479K - As Isolated form
分子名称: CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ...
著者Carr, S.B, Beaton, S.E, Evans, R.M, Armstrong, F.A.
登録日2019-09-30
公開日2020-10-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Hydrogen activation by NiFe-hydrogenases - consolidating the role of the pendant arginine.
To Be Published
6SYP
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BU of 6syp by Molmil
Human DHODH bound to inhibitor IPP/CNRS-A017
分子名称: 2-[4-[2,6-bis(fluoranyl)phenoxy]-5-methyl-3-propan-2-yloxy-pyrazol-1-yl]-5-cyclopropyl-3-fluoranyl-pyridine, Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, ...
著者Kraemer, A, Janin, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2019-09-30
公開日2019-10-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor
Eur.J.Med.Chem., 208, 2020
6SYX
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BU of 6syx by Molmil
Hydrogenase-2 variant R479K - reduced sample exposed to pure oxygen
分子名称: CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ...
著者Carr, S.B, Beaton, S.E, Evans, R.M, Armstrong, F.A.
登録日2019-10-01
公開日2020-10-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Hydrogen activation by NiFe-hydrogenases - consolidating the role of the pendant arginine.
To Be Published

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件を2024-07-31に公開中

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