6SXU

GH51 a-l-arabinofuranosidase soaked with cyclic sulfate inhibitor

This is a non-PDB format compatible entry.

Summary for 6SXU

• Entry DOI: 10.2210/pdb6sxu/pdb
• Descriptor: Intracellular exo-alpha-(1->5)-L-arabinofuranosidase, [(1~{S},2~{S},3~{S},4~{S})-2-(hydroxymethyl)-3,4-bis(oxidanyl)cyclopentyl] hydrogen sulfate, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
• Functional Keywords: covalent complex, arabinofuranosidase, gh51, geobacillus, hydrolase
• Biological source: Geobacillus stearothermophilus
• Total number of polymer chains: 2
• Total formula weight: 115773.08

Authors

McGregor, N.G.S.,Davies, G.J. (deposition date: 2019-09-26, release date: 2020-02-26, Last modification date: 2024-01-24)

• Primary citation: McGregor, N.G.S.,Artola, M.,Nin-Hill, A.,Linzel, D.,Haon, M.,Reijngoud, J.,Ram, A.,Rosso, M.N.,van der Marel, G.A.,Codee, J.D.C.,van Wezel, G.P.,Berrin, J.G.,Rovira, C.,Overkleeft, H.S.,Davies, G.J.; Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining alpha-l-Arabinofuranosidases.; J.Am.Chem.Soc., 142:4648-4662, 2020; PubMed: 32053363; DOI: 10.1021/jacs.9b11351

Experimental method

X-RAY DIFFRACTION (1.398 Å)