Cryo-EM structure of the human Ebp1-ribosome complex

This is a large structure.

Summary for 6SXO

EMDB information10608 10609 10344
DescriptorProliferation-associated protein 2G4, 60S ribosomal protein L35, 60S ribosomal protein L38, ... (8 entities in total)
Functional Keywordshuman ebp1, pa2g4 family, met-ap homolog, expansion segment es27l, ribosome
Biological sourceHomo sapiens (Human)
Total number of polymer chains8
Total molecular weight1815935.23
Wild, K.,Aleksic, M.,Pfeffer, M.,Sinning, I. (deposition date: 2019-09-26, release date: 2020-02-19)
Primary citation
Wild, K.,Aleksic, M.,Lapouge, K.,Juaire, K.D.,Flemming, D.,Pfeffer, S.,Sinning, I.
MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments.
Nat Commun, 11:776-776, 2020
PubMed: 32034140 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-020-14603-7
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone60 1.3% 0.48MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload