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Showing 1 - 50 of 148 items for (author: spencer & t)

EMDB-72383:
Cryo-EM structure of human VCP/p97-R89W mutant bound to ADP
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

EMDB-72384:
Cryo-EM structure of human VCP/p97-R89W mutant bound to ATPgammaS
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

EMDB-72385:
Cryo-EM structure of human VCP/p97-R89W mutant bound to CB-5083
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

EMDB-72386:
Cryo-EM structure of human VCP/p97-T122P mutant bound to ADP
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

EMDB-72387:
Cryo-EM structure of human VCP/p97-T122P mutant bound to ATPgammaS
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

EMDB-72388:
Cryo-EM structure of human VCP/p97-G128D mutant bound to ADP
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

EMDB-72389:
Cryo-EM structure of human VCP/p97-G128D mutant bound to ATPgS
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

EMDB-72390:
Cryo-EM structure of human VCP/p97-G156D mutant bound to ADP
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

EMDB-72391:
Cryo-EM structure of human VCP/p97-G156D mutant bound to ATPgammaS
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

PDB-9y03:
Cryo-EM structure of human VCP/p97-R89W mutant bound to ADP
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

PDB-9y04:
Cryo-EM structure of human VCP/p97-R89W mutant bound to ATPgammaS
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

PDB-9y05:
Cryo-EM structure of human VCP/p97-R89W mutant bound to CB-5083
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

PDB-9y06:
Cryo-EM structure of human VCP/p97-T122P mutant bound to ADP
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

PDB-9y07:
Cryo-EM structure of human VCP/p97-T122P mutant bound to ATPgammaS
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

PDB-9y08:
Cryo-EM structure of human VCP/p97-G128D mutant bound to ADP
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

PDB-9y09:
Cryo-EM structure of human VCP/p97-G128D mutant bound to ATPgS
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

PDB-9y0b:
Cryo-EM structure of human VCP/p97-G156D mutant bound to ADP
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

PDB-9y0c:
Cryo-EM structure of human VCP/p97-G156D mutant bound to ATPgammaS
Method: single particle / : Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS

EMDB-53847:
Cryo-EM structure of human ATP citrate lyase in complex with inhibitor EVT0185-CoA
Method: single particle / : Verstraete K, Verschueren K, Savvides SN, Steinberg GR

PDB-9r90:
Cryo-EM structure of human ATP citrate lyase in complex with inhibitor EVT0185-CoA
Method: single particle / : Verstraete K, Verschueren K, Savvides SN, Steinberg GR

EMDB-70557:
Cardiac lambda-6 light chain amyloid AL-224L single protofilament
Method: helical / : Hicks CW, Gursky O, Huda N

PDB-9oka:
Cardiac lambda-6 light chain amyloid AL-224L single protofilament
Method: helical / : Hicks CW, Gursky O, Huda N

EMDB-49728:
TMPRSS6 in complex with REGN7999 Fab and REGN8023 Fab
Method: single particle / : Saotome K, Franklin MC

PDB-9nrc:
TMPRSS6 in complex with REGN7999 Fab and REGN8023 Fab
Method: single particle / : Saotome K, Franklin MC

EMDB-61842:
CryoEM structure of M. tuberculosis ClpC1P1P2 complex bound to bortezomib, conformation 3
Method: single particle / : Zhou B, Zhao H, Gao Y, Chen X, Zhang T, He J, Xiong X

EMDB-61847:
CryoEM structure of M. tuberculosis ClpP1P2 bound to bortezomib
Method: single particle / : Zhou B, Zhao H, Gao Y, Chen W, Zhang T, He J, Xiong X

PDB-9jvp:
CryoEM structure of M. tuberculosis ClpC1P1P2 complex bound to bortezomib, conformation 3
Method: single particle / : Zhou B, Zhao H, Gao Y, Chen X, Zhang T, He J, Xiong X

PDB-9jvz:
CryoEM structure of M. tuberculosis ClpP1P2 bound to bortezomib
Method: single particle / : Zhou B, Zhao H, Gao Y, Chen W, Zhang T, He J, Xiong X

EMDB-39157:
CryoEM structure of M. tuberculosis ClpC1P1P2 complex bound to bortezomib, conformation 2
Method: single particle / : Zhou B, Zhao H, Gao Y, Chen X, Zhang T, He J, Xiong X

EMDB-39161:
CryoEM structure of M. tuberculosis ClpXP1P2 complex bound to bortezomib
Method: single particle / : Zhou B, Zhao H, Gao Y, Chen X, Zhang T, He J, Xiong X

EMDB-39162:
CryoEM structure of M. tuberculosis ClpC1P1P2 complex bound to bortezomib, conformation 1
Method: single particle / : Zhou B, Zhao H, Gao Y, Chen X, Zhang T, He J, Xiong X

EMDB-39163:
CryoEM structure of M. tuberculosis ClpP1P2 bound to bortezomib
Method: single particle / : Zhou B, Gao Y, Zhao H, Chen W, He J, Zhang T, Xiong X

EMDB-39164:
CryoEM structure of apo M. tuberculosis ClpP1P2
Method: single particle / : Zhou B, Gao Y, Zhao H, Chen X, He J, Zhang T, Xiong X

EMDB-19627:
Cryo-EM structure of CAK modified by covalent inhibitor SY-1365
Method: single particle / : Feng J, Koh AF, Kotecha A, Greber BJ

EMDB-19628:
Cryo-EM structure of CAK in complex with SY-5609
Method: single particle / : Feng J, Cronin NB, Marineau JJ, Greber BJ

PDB-8s0r:
Cryo-EM structure of CAK modified by covalent inhibitor SY-1365
Method: single particle / : Feng J, Koh AF, Kotecha A, Greber BJ

PDB-8s0t:
Cryo-EM structure of CAK in complex with SY-5609
Method: single particle / : Feng J, Cronin NB, Marineau JJ, Greber BJ

EMDB-40825:
10E8-GT10.2 immunogen in complex with human Fab 10E8 and mouse Fab W6-10
Method: single particle / : Huang J, Ozorowski G, Ward AB

PDB-8sx3:
10E8-GT10.2 immunogen in complex with human Fab 10E8 and mouse Fab W6-10
Method: single particle / : Huang J, Ozorowski G, Ward AB

EMDB-18207:
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide, Glacios map
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-18230:
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-18915:
Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB-BRD4 BD2
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

PDB-8q7r:
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

PDB-8r5h:
Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB-BRD4 BD2
Method: single particle / : Liwocha J, Prabu JR, Kleiger G, Schulman BA

EMDB-43320:
Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein
Method: single particle / : Zhu X, Mannar D, Saville J, Poloni C, Bezeruk A, Tidey K, Ahmed S, Tuttle K, Vahdatihassani F, Cholak S, Cook L, Steiner TS, Subramaniam S

EMDB-43321:
Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with mouse ACE2 (conformation 2)
Method: single particle / : Zhu X, Mannar D, Saville J, Poloni C, Bezeruk A, Tidey K, Ahmed S, Tuttle K, Vahdatihassani F, Cholak S, Cook L, Steiner TS, Subramaniam S

EMDB-43322:
Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with mouse ACE2 (conformation 1)
Method: single particle / : Zhu X, Mannar D, Saville J, Poloni C, Bezeruk A, Tidey K, Ahmed S, Tuttle K, Vahdatihassani F, Cholak S, Cook L, Steiner TS, Subramaniam S

EMDB-43323:
Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with mouse ACE2 (focused refinement of RBD and mouse ACE2)
Method: single particle / : Zhu X, Mannar D, Saville J, Poloni C, Bezeruk A, Tidey K, Ahmed S, Tuttle K, Vahdatihassani F, Cholak S, Cook L, Steiner TS, Subramaniam S

EMDB-43324:
Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with human ACE2
Method: single particle / : Zhu X, Mannar D, Saville J, Poloni C, Bezeruk A, Tidey K, Ahmed S, Tuttle K, Vahdatihassani F, Cholak S, Cook L, Steiner TS, Subramaniam S

EMDB-43325:
Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with human ACE2 (focused refinement of RBD and ACE2)
Method: single particle / : Zhu X, Mannar D, Saville J, Poloni C, Bezeruk A, Tidey K, Ahmed S, Tuttle K, Vahdatihassani F, Cholak S, Cook L, Steiner TS, Subramaniam S

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