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Showing 1 - 50 of 2,395 items for (author: hu & hl)

EMDB-76459:
Cryo-EM density of the [NiFe]-hydrogenase HoxEFU diaphorase subcomplex
Method: single particle / : Ziegler SJ, Gruber JN

EMDB-71756:
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened consensus map from cryoSPARC non-uniform refinement)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71757:
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened AHD1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71758:
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened AHD2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71759:
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened CORE1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71760:
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened CORE2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71761:
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened WalkerB1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71762:
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened WalkerB2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71763:
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened NBD1 plus T2a local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71764:
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened NBD2 plus T2a local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71765:
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened T2a plus T2a local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-48304:
Cryo-EM structure of human NBCn2
Method: single particle / : Yang S, Capper MJ, Zilberg G, Warren AL, Wacker D

EMDB-48318:
Cryo-EM structure of human NBCn2 bound to Carbonate
Method: single particle / : Yang S, Capper MJ, Zilberg G, Warren AL, Wacker D

EMDB-48320:
Cryo-EM structure of human NBCn2 bound to Compound 38J
Method: single particle / : Yang S, Capper MJ, Zilberg G, Warren AL, Wacker D

EMDB-54904:
Structure of trans-basal conformer of human CBS trapped in PLP-aminoacrylate intermediate state (CBS PLP-AA)- by single particle approach
Method: single particle / : Inayathulla M, Tomas M

EMDB-54905:
Structure of trans-basal conformer of human CBS trapped in PLP-serine external aldemine intermediate (CBS-PLP-Ser)- by single particle approach
Method: single particle / : Inayathulla M, Tomas M

EMDB-54925:
Structure of trans-basal conformer of human CBS trapped in PLP-aminoacrylate intermediate state (CBS PLP-AA)- by Helical processing.
Method: helical / : Inayathulla M, Tomas M

EMDB-55037:
Structure of trans-basal conformer of human CBS trapped in PLP-serine external aldemine intermediate (CBS-PLP-Ser)- by Helical approach
Method: helical / : Inayathulla M, Tomas M

EMDB-55097:
focused structure of regulatory domains of cis-basal conformer of human CBS induced by non-activating allosteric SAO ligand - by Helical approach
Method: helical / : Inayathulla M, Tomas M

EMDB-55099:
Structure of cis-basal conformer of human CBS induced by non-activating allosteric SAO ligand - by single particle approach.
Method: single particle / : Inayathulla M, Tomas M

EMDB-55105:
Structure of trans-basal conformer of wild-type human CBS alone (internal aldemine)- by single particle approach
Method: single particle / : Inayathulla M, Tomas M

EMDB-55115:
Structure of trans-basal conformer of wild-type human CBS enzyme in absence of substrate and allosteric activators- by Helical approach
Method: helical / : Inayathulla M, Tomas M

PDB-9shm:
Structure of trans-basal conformer of human CBS trapped in PLP-aminoacrylate intermediate state (CBS PLP-AA)- by single particle approach
Method: single particle / : Inayathulla M, Tomas M

PDB-9shn:
Structure of trans-basal conformer of human CBS trapped in PLP-serine external aldemine intermediate (CBS-PLP-Ser)- by single particle approach
Method: single particle / : Inayathulla M, Tomas M

PDB-9si8:
Structure of trans-basal conformer of human CBS trapped in PLP-aminoacrylate intermediate state (CBS PLP-AA)- by Helical processing.
Method: helical / : Inayathulla M, Tomas M

PDB-9sml:
Structure of trans-basal conformer of human CBS trapped in PLP-serine external aldemine intermediate (CBS-PLP-Ser)- by Helical approach
Method: helical / : Inayathulla M, Tomas M

PDB-9spv:
focused structure of regulatory domains of cis-basal conformer of human CBS induced by non-activating allosteric SAO ligand - by Helical approach
Method: helical / : Inayathulla M, Tomas M

PDB-9spw:
Structure of cis-basal conformer of human CBS induced by non-activating allosteric SAO ligand - by single particle approach.
Method: single particle / : Inayathulla M, Tomas M

PDB-9sq0:
Structure of trans-basal conformer of wild-type human CBS alone (internal aldemine)- by single particle approach
Method: single particle / : Inayathulla M, Tomas M

PDB-9sqq:
Structure of trans-basal conformer of wild-type human CBS enzyme in absence of substrate and allosteric activators- by Helical approach
Method: helical / : Inayathulla M, Tomas M

EMDB-71698:
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened AHD1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71709:
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened AHD2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71710:
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened CORE1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71711:
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened CORE2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71713:
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened WalkerB2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71714:
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened T2a local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-75346:
Membrane protein solubilization and structure determination using de novo-designed amphipathic proteins
Method: single particle / : Borst AJ, Weidle C

EMDB-75350:
WRAP-TP0698
Method: single particle / : Borst AJ

EMDB-68793:
Vpb4Aa2 pore complex in C1 symmetry
Method: single particle / : Wirawan R, Spicer BA, Lupton CJ, Venugopal H, Berry C, Dunstone MA

EMDB-71647:
Vpb4Aa2 pore complex in C7 symmetry
Method: single particle / : Wirawan R, Spicer BA, Lupton CJ, Venugopal H, Berry C, Dunstone MA

EMDB-57856:
Structure of human Trpm4 in native lipid vesicles at 8 degrees celsius
Method: single particle / : Schneiter D, Ekundayo B, Stahlberg H, Abriel H

PDB-30kh:
Structure of human Trpm4 in native lipid vesicles at 8 degrees celsius
Method: single particle / : Schneiter D, Ekundayo B, Stahlberg H, Abriel H

EMDB-54772:
C1 map of the filament formed by the grappling-hook like protein A from L. aerophila
Method: single particle / : Joest M, Mollat CL, Sivabalasarma S, Albers SV

EMDB-54773:
C3 map of the filament formed by the grappling-hook like protein A from L. aerophila
Method: single particle / : Joest M, Mollat CL, Sivabalasarma S, Albers SV

EMDB-54780:
CryoET of L. aerophila cell
Method: electron tomography / : Joest M, Sivabalasarma S, Mollat CL, Albers SV

EMDB-54781:
CryoET of cell pole of L. aerophila
Method: electron tomography / : Joest M, Sivabalasarma S, Mollat CL, Albers SV

EMDB-57253:
CryoET of archaellated cell pole of L. aerophila
Method: electron tomography / : Joest M, Sivabalasarma S, Mollat CL, Albers SV

EMDB-72009:
Q10M-055 Fab in complex with HIV-1 Env Q23 NFL TD CC3+
Method: single particle / : Phulera S, Ozorowski G, Ward AB

EMDB-72031:
Q12QBM-007 Fab in complex with HIV-1 Env BG505 NFL TD CC3+
Method: single particle / : Phulera S, Ozorowski G, Ward AB

EMDB-72033:
Q9M-023 Fab in complex with HIV-1 Env BG505 NFL TD CC3+
Method: single particle / : Phulera S, Ozorowski G, Ward AB

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

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