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-Structure paper
| Title | Deep mining of the human antibody repertoire identifies frequent and genetically diverse CDRH3 topologies targetable by vaccination. |
|---|---|
| Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 123, Page e2532810123-e2532810123, Year 2026 |
| Publish date | Sep 4, 2024 (structure data deposition date) |
 Authors | Habib, R. / Solieva, S.O. / Lin, Z.J. / Ghosh, S. / Bayruns, K. / Singh, M. / Agostino, C.J. / Tursi, N.J. / Sowers, K.J. / Huang, J. ...Habib, R. / Solieva, S.O. / Lin, Z.J. / Ghosh, S. / Bayruns, K. / Singh, M. / Agostino, C.J. / Tursi, N.J. / Sowers, K.J. / Huang, J. / Roark, R.S. / Purwar, M. / Park, Y. / Ayyanathan, K. / Li, H. / Carey, J.W. / Kim, A. / Park, J. / McCanna, M.E. / Skelly, A.N. / Chokkalingam, N. / Kriete, S. / Shupin, N. / Huynh, A. / Walker, S. / Sadeesh, R. / Laenger, N. / Du, J. / Cui, J. / Patel, A. / Escolano, A. / Kwong, P.D. / Shapiro, L. / Bowman, G.R. / Hahn, B.H. / Shaw, G.M. / Weiner, D.B. / Pallesen, J. / Kulp, D.W. |
 External links | Proc. Natl. Acad. Sci. USA / PubMed:42054357 |
| Methods | EM (single particle) |
| Resolution | 3.19 - 3.49 Å |
| Structure data |  PDB-9dhw:  PDB-9dim:  PDB-9z9l: |
| Chemicals |  ChemComp-NAG: |
| Source |
|
 Keywords | VIRAL PROTEIN/IMMUNE SYSTEM / Antibody / Complex / VIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex / HIV-1 Env / VIRUS |
human immunodeficiency virus 1
homo sapiens (human)