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-Structure paper
| Title | Architecture of the UBR4 complex, a giant E4 ligase central to eukaryotic protein quality control |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Jan 8, 2025 (structure data deposition date) |
Authors | Grabarczyk DB / Ehrmann JF / Murphy P / Kurzbauer R / Bell LE / Deszcz L / Neuhold J / Schleiffer A / Shulkina A / Versteeg GA ...Grabarczyk DB / Ehrmann JF / Murphy P / Kurzbauer R / Bell LE / Deszcz L / Neuhold J / Schleiffer A / Shulkina A / Versteeg GA / Meinhart A / Zavodszky E / Hegde RS / Clausen T |
External links | Search PubMed |
| Methods | EM (single particle) |
| Resolution | 3.1 - 5.7 Å |
| Structure data | EMDB-52490, PDB-9hxw: ![]() EMDB-52492: Cryo-EM structure of human UBR4/KCMF1/CALM1 (N-term focused refinement) ![]() EMDB-52511: Cryo-EM structure of the C. elegans UBR4/KCMF1 complex (side focused refinement) ![]() EMDB-52515: Cryo-EM structure of the C. elegans UBR4/KCMF1 complex (N-term focused refinement) |
| Chemicals | ![]() ChemComp-ZN: |
| Source |
|
Keywords | LIGASE / Ubiquitin ligase Protein quality control |
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homo sapiens (human)
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