Author results

1P33
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PTERIDINE REDUCTASE FROM LEISHMANIA TARENTOLAE COMPLEX WITH NADPH AND MTX
Descriptor:Pteridine reductase 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, METHOTREXATE
Authors:Zhao, H., Bray, T., Ouellette, M., Zhao, M., Ferre, R.A., Matthews, D., Whiteley, J.M., Varughese, K.I.
Deposit date:2003-04-16
Release date:2003-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structure of pteridine reductase (PTR1) from Leishmania tarentolae.
Acta Crystallogr.,Sect.D, 59, 2003
1BK9
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PHOSPHOLIPASE A2 MODIFIED BY PBPB
Descriptor:PHOSPHOLIPASE A2, CALCIUM ION, 1-(4-BROMO-PHENYL)-ETHANONE, ...
Authors:Zhao, H., Tang, L., Wang, X., Lin, Z., Zhou, Y.
Deposit date:1998-07-16
Release date:1999-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a snake venom phospholipase A2 modified by p-bromo-phenacyl-bromide.
Toxicon, 36, 1998
1LQ1
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DNA COMPLEXED STRUCTURE OF THE KEY TRANSCRIPTION FACTOR INITIATING DEVELOPMENT IN SPORULATION BACTERIA
Descriptor:5'-D(*TP*TP*CP*GP*TP*GP*TP*CP*GP*AP*AP*TP*TP*TP*TP*G)-3', 5'-D(*AP*CP*AP*AP*AP*AP*TP*TP*CP*GP*AP*CP*AP*CP*GP*A)-3', Stage 0 sporulation protein A
Authors:Zhao, H., Msadek, T., Zapf, J., Madhusudan, Hoch, J.A., Varughese, K.I.
Deposit date:2002-05-08
Release date:2002-08-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:DNA complexed structure of the key transcription factor initiating development in sporulating bacteria.
Structure, 10, 2002
1XBO
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PTP1B COMPLEXED WITH ISOXAZOLE CARBOXYLIC ACID
Descriptor:Protein-tyrosine phosphatase, non-receptor type 1, 5-(3-{3-[3-HYDROXY-2-(METHOXYCARBONYL)PHENOXY]PROPENYL}PHENYL)-4-(HYDROXYMETHYL)ISOXAZOLE-3-CARBOXYLIC ACID
Authors:Zhao, H., Liu, G., Xin, Z., Serby, M., Pei, Z., Szczepankiewicz, B.G., Hajduk, P.J., Abad-Zapatero, C., Hutchins, C.W., Lubben, T.H., Ballaron, S.J., Hassach, D.L., Kaszubska, W., Rondinone, C.M., Trevillyan, J.M., Jirousek, M.R.
Deposit date:2004-08-31
Release date:2004-10-19
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
2ZKZ
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CRYSTAL STRUCTURE OF THE TRANSCRIPTIONAL REPRESSOR PAGR OF BACILLUS ANTHRACIS
Descriptor:Transcriptional repressor pagR
Authors:Zhao, H., Volkov, A., Veldore, V.H., Varughese, K.I.
Deposit date:2008-04-01
Release date:2009-04-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the transcriptional repressor PagR of Bacillus anthracis
Microbiology, 156, 2010
3F6P
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CRYSTAL STRUCTURE OF UNPHOSPHORELATED RECEIVER DOMAIN OF YYCF
Descriptor:Transcriptional regulatory protein yycF
Authors:Zhao, H., Tang, L.
Deposit date:2008-11-06
Release date:2010-03-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Preliminary crystallographic studies of the regulatory domain of response regulator YycF from an essential two-component signal transduction system.
Acta Crystallogr.,Sect.F, 65, 2009
3HEF
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CRYSTAL STRUCTURE OF THE BACTERIOPHAGE SF6 TERMINASE SMALL SUBUNIT
Descriptor:Gene 1 protein
Authors:Zhao, H., Tang, L.
Deposit date:2009-05-08
Release date:2010-02-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the DNA-recognition component of the bacterial virus Sf6 genome-packaging machine
Proc.Natl.Acad.Sci.USA, 107, 2010
3NB3
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THE HOST OUTER MEMBRANE PROTEINS OMPA AND OMPC ARE PACKED AT SPECIFIC SITES IN THE SHIGELLA PHAGE SF6 VIRION AS STRUCTURAL COMPONENTS
Descriptor:Outer membrane protein A, Outer membrane protein C
Authors:Zhao, H., Sequeira, R.D., Galeva, N.A., Tang, L.
Deposit date:2010-06-02
Release date:2011-02-16
Last modified:2016-11-09
Method:ELECTRON MICROSCOPY (19 Å)
Cite:The host outer membrane proteins OmpA and OmpC are associated with the Shigella phage Sf6 virion.
Virology, 409, 2011
4DYC
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CRYSTAL STRUCTURE OF THE TERMINASE SMALL SUBUNIT GP1 WITH D19R MUTATION OF THE BACTERIAL VIRUS SF6
Descriptor:Terminase small subunit
Authors:Zhao, H., Tang, L.
Deposit date:2012-02-28
Release date:2012-10-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Functional Studies of the Phage Sf6 Terminase Small Subunit Reveal a DNA-Spooling Device Facilitated by Structural Plasticity.
J.Mol.Biol., 423, 2012
4DYQ
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HIGH RESOLUTION CRYSTAL STRUCTURE OF TERMINASE SMALL SUBUNIT GP1 OF THE BACTERIAL VIRUS SF6
Descriptor:Gene 1 protein
Authors:Zhao, H., Tang, L.
Deposit date:2012-02-29
Release date:2012-10-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Structural and Functional Studies of the Phage Sf6 Terminase Small Subunit Reveal a DNA-Spooling Device Facilitated by Structural Plasticity.
J.Mol.Biol., 423, 2012
4DYR
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CRYSTAL STRUCTURE OF TERMINASE SMALL SUBUNIT GP1 OF THE BACTERIAL VIRUS SF6 WITH CAPS PH10.5 BUFFER
Descriptor:Gene 1 protein
Authors:Zhao, H., Tang, L.
Deposit date:2012-02-29
Release date:2012-10-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural and Functional Studies of the Phage Sf6 Terminase Small Subunit Reveal a DNA-Spooling Device Facilitated by Structural Plasticity.
J.Mol.Biol., 423, 2012
4DZJ
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CRYSTAL STRUCTURE OF THE TERMINASE SMALL SUBUNIT GP1 WITH K59E MUTATION OF THE BACTERIAL VIRUS SF6
Descriptor:Gene 1 protein
Authors:Zhao, H., Tang, L.
Deposit date:2012-03-01
Release date:2012-10-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Studies of the Phage Sf6 Terminase Small Subunit Reveal a DNA-Spooling Device Facilitated by Structural Plasticity.
J.Mol.Biol., 423, 2012
4DZP
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CRYSTAL STRUCTURE OF THE TERMINASE SMALL SUBUNIT GP1 WITH R48A MUTATION OF THE BACTERIAL VIRUS SF6
Descriptor:Gene 1 protein
Authors:Zhao, H., Tang, L.
Deposit date:2012-03-01
Release date:2012-10-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Functional Studies of the Phage Sf6 Terminase Small Subunit Reveal a DNA-Spooling Device Facilitated by Structural Plasticity.
J.Mol.Biol., 423, 2012
4IDH
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CRYSTAL STRUCTURE OF THE LARGE TERMINASE SUBUNIT GP2 OF BACTERIAL VIRUS SF6
Descriptor:Gene 2 protein
Authors:Zhao, H., Christensen, T., Kamau, Y., Tang, L.
Deposit date:2012-12-12
Release date:2013-05-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structures of the phage Sf6 large terminase provide new insights into DNA translocation and cleavage.
Proc.Natl.Acad.Sci.USA, 110, 2013
4IEE
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CRYSTAL STRUCTURE OF THE LARGE TERMINASE SUBUNIT GP2 OF BACTERIAL VIRUS SF6 COMPLEXED WITH ATP-R-S
Descriptor:Gene 2 protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Zhao, H., Christensen, T., Kamau, Y., Tang, L.
Deposit date:2012-12-13
Release date:2013-05-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structures of the phage Sf6 large terminase provide new insights into DNA translocation and cleavage.
Proc.Natl.Acad.Sci.USA, 110, 2013
4IEI
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CRYSTAL STRUCTURE OF THE LARGE TERMINASE SUBUNIT GP2 OF BACTERIAL VIRUS SF6 COMPLEXED WITH ADP
Descriptor:Gene 2 protein, ADENOSINE-5'-DIPHOSPHATE
Authors:Zhao, H., Christensen, T., Kamau, Y., Tang, L.
Deposit date:2012-12-13
Release date:2013-05-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structures of the phage Sf6 large terminase provide new insights into DNA translocation and cleavage.
Proc.Natl.Acad.Sci.USA, 110, 2013
4IFE
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CRYSTAL STRUCTURE OF THE LARGE TERMINASE SUBUNIT GP2 OF BACTERIAL VIRUS SF6 COMPLEXED WITH ATP
Descriptor:Gene 2 protein, ADENOSINE-5'-TRIPHOSPHATE
Authors:Zhao, H., Christensen, T., Kamau, Y., Tang, L.
Deposit date:2012-12-14
Release date:2013-05-01
Last modified:2013-05-29
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structures of the phage Sf6 large terminase provide new insights into DNA translocation and cleavage.
Proc.Natl.Acad.Sci.USA, 110, 2013
4U7U
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CRYSTAL STRUCTURE OF RNA-GUIDED IMMUNE CASCADE COMPLEX FROM E.COLI
Descriptor:CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasE, ...
Authors:Zhao, H., Sheng, G., Wang, J., Wang, M., Bunkoczi, G., Gong, W., Wei, Z., Wang, Y.
Deposit date:2014-07-31
Release date:2014-08-27
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli
Nature, 515, 2014
5AGH
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CRYSTAL STRUCTURE OF THE LEURS EDITING DOMAIN OF CANDIDA ALBICANS MUTANT K510A
Descriptor:POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE, ACETATE ION
Authors:Zhao, H., Palencia, A., Seiradake, E., Ghaemi, Z., Luthey-Schulten, Z., Cusack, S., Martinis, S.A.
Deposit date:2015-02-02
Release date:2015-07-01
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism.
Acs Chem.Biol., 10, 2015
5AGI
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CRYSTAL STRUCTURE OF THE LEURS EDITING DOMAIN OF CANDIDA ALBICANS MUTANT K510A IN COMPLEX WITH THE ADDUCT FORMED BY AN2690-AMP
Descriptor:POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE, [(6-AMINO-9H-PURIN-9-YL)-[5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE]-4'YL]METHYL DIHYDROGEN PHOSPHATE, GLYCEROL
Authors:Zhao, H., Palencia, A., Seiradake, E., Ghaemi, Z., Luthey-Schulten, Z., Cusack, S., Martinis, S.A.
Deposit date:2015-02-02
Release date:2015-07-01
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism.
Acs Chem.Biol., 10, 2015
5AGJ
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CRYSTAL STRUCTURE OF THE LEURS EDITING DOMAIN OF CANDIDA ALBICANS IN COMPLEX WITH THE ADDUCT AN2690-AMP
Descriptor:POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE, [(6-AMINO-9H-PURIN-9-YL)-[5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE]-4'YL]METHYL DIHYDROGEN PHOSPHATE
Authors:Zhao, H., Palencia, A., Seiradake, E., Ghaemi, Z., Luthey-Schulten, Z., Cusack, S., Martinis, S.A.
Deposit date:2015-02-02
Release date:2015-07-01
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism.
Acs Chem.Biol., 10, 2015
5C10
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NUCLEASE DOMAIN OF THE LARGE TERMINASE SUBUNIT GP2 OF BACTERIAL VIRUS SF6
Descriptor:Gene 2 protein
Authors:Zhao, H., Tang, L.
Deposit date:2015-06-12
Release date:2015-10-21
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism.
Nucleic Acids Res., 43, 2015
5C12
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NUCLEASE DOMAIN OF THE LARGE TERMINASE SUBUNIT GP2 OF BACTERIAL VIRUS SF6
Descriptor:Gene 2 protein, MAGNESIUM ION
Authors:Zhao, H., Tang, L.
Deposit date:2015-06-12
Release date:2015-10-21
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.517 Å)
Cite:Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism.
Nucleic Acids Res., 43, 2015
5C15
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K428A MUNTANT NUCLEASE DOMAIN OF THE LARGE TERMINASE SUBUNIT GP2 OF BACTERIAL VIRUS SF6 WITH MANGANESE
Descriptor:Gene 2 protein, MANGANESE (II) ION
Authors:Zhao, H., Tang, L.
Deposit date:2015-06-12
Release date:2015-10-21
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism.
Nucleic Acids Res., 43, 2015
5C2D
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K428A MUTANT GP2C OF LARGE TERMINASE SUBUNIT FROM BACTERIOPHAGE SF6 WITH CALCIUM
Descriptor:Gene 2 protein, CALCIUM ION
Authors:Zhao, H., Tang, L.
Deposit date:2015-06-15
Release date:2015-10-21
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism.
Nucleic Acids Res., 43, 2015