5C12

Nuclease domain of the large terminase subunit gp2 of bacterial virus Sf6

Summary for 5C12

Entry DOI	10.2210/pdb5c12/pdb
Related	4IDH 5C10 5C15 5C2D 5C2F
Descriptor	Gene 2 protein, MAGNESIUM ION (3 entities in total)
Functional Keywords	nuclease domain, metal binding site, k428a mutant, metal binding protein
Biological source	Enterobacteria phage Sf6 (Shigella flexneri bacteriophage VI)
Total number of polymer chains	1
Total formula weight	30770.19
Authors	Zhao, H.,Tang, L. (deposition date: 2015-06-12, release date: 2015-10-21, Last modification date: 2024-03-06)
Primary citation	Zhao, H.,Lin, Z.,Lynn, A.Y.,Varnado, B.,Beutler, J.A.,Murelli, R.P.,Le Grice, S.F.,Tang, L. Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism. Nucleic Acids Res., 43:11003-11016, 2015 Cited by PubMed: 26450964 DOI: 10.1093/nar/gkv1018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.517 Å)

Structure validation