1P33

Pteridine reductase from Leishmania tarentolae complex with NADPH and MTX

Summary for 1P33

Related1E7w 1E92
DescriptorPteridine reductase 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, METHOTREXATE, ... (4 entities in total)
Functional Keywordspteridine reductase, complex, nadph, mtx, oxidoreductase
Biological sourceLeishmania tarentolae
Total number of polymer chains4
Total molecular weight127890.5
Authors
Zhao, H.,Bray, T.,Ouellette, M.,Zhao, M.,Ferre, R.A.,Matthews, D.,Whiteley, J.M.,Varughese, K.I. (deposition date: 2003-04-16, release date: 2003-09-02, Last modification date: 2011-07-13)
Primary citation
Zhao, H.,Bray, T.,Ouellette, M.,Zhao, M.,Ferre, R.A.,Matthews, D.,Whiteley, J.M.,Varughese, K.I.
Structure of pteridine reductase (PTR1) from Leishmania tarentolae.
Acta Crystallogr.,Sect.D, 59:1539-1544, 2003
PubMed: 12925782 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444903013131
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.86 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24423 2.0% 3.9% 3.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02