5AGH
Crystal structure of the LeuRS editing domain of Candida albicans Mutant K510A
Summary for 5AGH
Entry DOI | 10.2210/pdb5agh/pdb |
Related | 5AGI 5AGJ 5AH5 |
Descriptor | POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE, ACETATE ION (3 entities in total) |
Functional Keywords | ligase, aminoacyl-trna synthetase, aminoacylation, protein synthesis, proof-reading mechanisms, antifungal target |
Biological source | CANDIDA ALBICANS |
Total number of polymer chains | 1 |
Total formula weight | 29557.52 |
Authors | Zhao, H.,Palencia, A.,Seiradake, E.,Ghaemi, Z.,Luthey-Schulten, Z.,Cusack, S.,Martinis, S.A. (deposition date: 2015-02-02, release date: 2015-07-01, Last modification date: 2024-01-10) |
Primary citation | Zhao, H.,Palencia, A.,Seiradake, E.,Ghaemi, Z.,Cusack, S.,Luthey-Schulten, Z.,Martinis, S. Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism. Acs Chem.Biol., 10:2277-, 2015 Cited by PubMed: 26172575DOI: 10.1021/ACSCHEMBIO.5B00291 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
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