Author results

1VHR
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HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE
Descriptor:HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE VHR, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION
Authors:Yuvaniyama, J., Denu, J.M., Dixon, J.E., Saper, M.A.
Deposit date:1996-02-20
Release date:1996-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the dual specificity protein phosphatase VHR.
Science, 272, 1996
1J3I
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WILD-TYPE PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH WR99210, NADPH, AND DUMP
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Yuvaniyama, J., Chitnumsub, P., Kamchonwongpaisan, S., Vanichtanankul, J., Sirawaraporn, W., Taylor, P., Walkinshaw, M., Yuthavong, Y.
Deposit date:2003-02-03
Release date:2003-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Insights into antifolate resistance from malarial DHFR-TS structures.
NAT.STRUCT.BIOL., 10, 2003
1J3J
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DOUBLE MUTANT (C59R+S108N) PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH PYRIMETHAMINE, NADPH, AND DUMP
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Yuvaniyama, J., Chitnumsub, P., Kamchonwongpaisan, S., Vanichtanankul, J., Sirawaraporn, W., Taylor, P., Walkinshaw, M., Yuthavong, Y.
Deposit date:2003-02-03
Release date:2003-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insights into antifolate resistance from malarial DHFR-TS structures.
NAT.STRUCT.BIOL., 10, 2003
1J3K
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QUADRUPLE MUTANT (N51I+C59R+S108N+I164L) PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH WR99210, NADPH, AND DUMP
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Yuvaniyama, J., Chitnumsub, P., Kamchonwongpaisan, S., Vanichtanankul, J., Sirawaraporn, W., Taylor, P., Walkinshaw, M., Yuthavong, Y.
Deposit date:2003-02-03
Release date:2003-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights into antifolate resistance from malarial DHFR-TS structures.
NAT.STRUCT.BIOL., 10, 2003
5ZYR
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CRYSTAL STRUCTURE OF THE REDUCTASE (C1) COMPONENT OF P-HYDROXYPHENYLACETATE 3-HYDROXYLASE (HPAH) FROM ACINETOBACTER BAUMANNII
Descriptor:p-hydroxyphenylacetate 3-hydroxylase, reductase component, FLAVIN MONONUCLEOTIDE, ...
Authors:Oonanant, W., Phongsak, T., Sucharitakul, J., Chaiyen, P., Yuvaniyama, J.
Deposit date:2018-05-28
Release date:2019-06-05
Method:X-RAY DIFFRACTION (2.200013 Å)
Cite:Crystal structure of the reductase (C1) component of p-hydroxyphenylacetate 3-hydroxylase (HPAH) from Acinetobacter baumannii
To Be Published
2GV0
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THE STRUCTURE OF THE ORTHORHOMBIC FORM OF SOFT-SHELLED TURTLE LYSOZYME AT 1.9 ANGSTROMS RESOLUTION
Descriptor:Lysozyme C, SULFATE ION
Authors:Siritapetawee, J., Thammasirirak, S., Yuvaniyama, J., Robinson, R.C.
Deposit date:2006-05-02
Release date:2007-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallization and the 1.9 angstroms of the egg-white lysozyme from a taiwanese soft-shelled turtle (trionyx sinensis wiegmann)
to be published
3AHT
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CRYSTAL STRUCTURE OF RICE BGLU1 E176Q MUTANT IN COMPLEX WITH LAMINARIBIOSE
Descriptor:Beta-glucosidase 7, 3-O-beta-D-glucopyranosyl-beta-D-glucopyranose, ZINC ION, ...
Authors:Chuenchor, W., Pengthaisong, S., Robinson, R.C., Yuvaniyama, J., Svasti, J., Ketudat Cairns, J.R.
Deposit date:2010-04-29
Release date:2010-06-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structural basis of oligosaccharide binding by rice BGlu1 beta-glucosidase
J.Struct.Biol., 173, 2011
3AHV
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SEMI-ACTIVE E176Q MUTANT OF RICE BGLU1 COVALENT COMPLEX WITH 2-DEOXY-2-FLUOROGLUCOSIDE
Descriptor:Beta-glucosidase 7, 2-deoxy-2-fluoro-alpha-D-glucopyranose, ZINC ION, ...
Authors:Chuenchor, W., Pengthaisong, S., Robinson, R.C., Yuvaniyama, J., Svasti, J., Ketudat Cairns, J.R.
Deposit date:2010-04-30
Release date:2010-06-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:The structural basis of oligosaccharide binding by rice BGlu1 beta-glucosidase
J.Struct.Biol., 173, 2011
3QFX
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TRYPANOSOMA BRUCEI DIHYDROFOLATE REDUCTASE PYRIMETHAMINE COMPLEX
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE
Authors:Vanichtanankul, J., Yuvaniyama, J., Taweechai, S., Chitnumsub, P., Kamchonwongpaisan, S., Yuthavong, Y.
Deposit date:2011-01-24
Release date:2011-06-29
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Trypanosomal dihydrofolate reductase reveals natural antifolate resistance
Acs Chem.Biol., 6, 2011
3QG2
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PLASMODIUM FALCIPARUM DHFR-TS QRADRUPLE MUTANT (N51I+C59R+S108N+I164L, V1/S) PYRIMETHAMINE COMPLEX
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Vanichtanankul, J., Yuvaniyama, J., Taweechai, S., Chitnumsub, P., Kamchonwongpaisan, S., Yuthavong, Y.
Deposit date:2011-01-24
Release date:2011-06-29
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Trypanosomal dihydrofolate reductase reveals natural antifolate resistance
Acs Chem.Biol., 6, 2011
3RG9
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TRYPANOSOMA BRUCEI DIHYDROFOLATE REDUCTASE (TBDHFR) IN COMPLEX WITH WR99210
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE
Authors:Vanichtanankul, J., Yuvaniyama, J., Yuthavong, Y.
Deposit date:2011-04-08
Release date:2011-06-29
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Trypanosomal dihydrofolate reductase reveals natural antifolate resistance
Acs Chem.Biol., 6, 2011
4DDR
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HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND P218
Descriptor:Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid
Authors:Yuthavong, Y., Tarnchompoo, B., Vilaivan, T., Chitnumsub, P., Kamchonwongpaisan, S., Charman, S.A., McLennan, D.N., White, K.L., Vivas, L., Bongard, E., Thongphanchang, C., Taweechai, S., Vanichtanankul, J., Rattanajak, R., Arwon, U., Fantauzzi, P., Yuvaniyama, J., Charman, W.N., Matthews, D.
Deposit date:2012-01-19
Release date:2012-11-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target
Proc.Natl.Acad.Sci.USA, 109, 2012
4DP3
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QUADRUPLE MUTANT (N51I+C59R+S108N+I164L) PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH P218 AND NADPH
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Yuthavong, Y., Vilaivan, T., Kamchonwongpaisan, S., Charman, S.A., McLennan, D.N., White, K.L., Vivas, L., Bongard, E., Chitnumsub, P., Tarnchompoo, B., Thongphanchang, C., Taweechai, S., Vanichtanakul, J., Arwon, U., Fantauzzi, P., Yuvaniyama, J., Charman, W.N., Matthews, D.
Deposit date:2012-02-13
Release date:2012-11-14
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target
Proc.Natl.Acad.Sci.USA, 109, 2012
4DPD
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WILD TYPE PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS), DHF COMPLEX, NADP+, DUMP
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, DIHYDROFOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Yuthavong, Y., Vilaivan, T., Kamchonwongpaisan, S., Charman, S.A., McLennan, D.N., White, K.L., Vivas, L., Bongard, E., Chitnumsub, P., Tarnchompoo, B., Thongphanchang, C., Taweechai, S., Vanichtanakul, J., Arwon, U., Fantauzzi, P., Yuvaniyama, J., Charman, W.N., Matthews, D.
Deposit date:2012-02-13
Release date:2012-11-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target
Proc.Natl.Acad.Sci.USA, 109, 2012
4DPH
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QUADRUPLE MUTANT (N51I+C59R+S108N+I164L) PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH P65 AND NADPH
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, 2,4-diamino-6-methyl-5-[3-(2,4,5-trichlorophenoxy)propyloxy]pyrimidine, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Yuthavong, Y., Vilaivan, T., Kamchonwongpaisan, S., Charman, S.A., McLennan, D.N., White, K.L., Vivas, L., Bongard, E., Chitnumsub, P., Tarnchompoo, B., Thongphanchang, C., Taweechai, S., Vanichtanakul, J., Arwon, U., Fantauzzi, P., Yuvaniyama, J., Charman, W.N., Matthews, D.
Deposit date:2012-02-13
Release date:2012-11-14
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target
Proc.Natl.Acad.Sci.USA, 109, 2012
2RGL
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RICE BGLU1 BETA-GLUCOSIDASE, A PLANT EXOGLUCANASE/BETA-GLUCOSIDASE
Descriptor:Beta-glucosidase, ZINC ION, SULFATE ION, ...
Authors:Chuenchor, W., Ketudat Cairns, J.R., Pengthaisong, S., Robinson, R.C., Yuvaniyama, J., Chen, C.-J.
Deposit date:2007-10-04
Release date:2008-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights into Rice BGlu1 beta-Glucosidase Oligosaccharide Hydrolysis and Transglycosylation
J.Mol.Biol., 377, 2008
2RGM
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RICE BGLU1 BETA-GLUCOSIDASE, A PLANT EXOGLUCANASE/BETA-GLUCOSIDASE
Descriptor:Beta-glucosidase, 2-deoxy-2-fluoro-alpha-D-glucopyranose, ZINC ION, ...
Authors:Chuenchor, W., Ketudat Cairns, J.R., Pengthaisong, S., Robinson, R.C., Yuvaniyama, J., Chen, C.-J.
Deposit date:2007-10-04
Release date:2008-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural Insights into Rice BGlu1 beta-Glucosidase Oligosaccharide Hydrolysis and Transglycosylation
J.Mol.Biol., 377, 2008
3F4V
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SEMI-ACTIVE E176Q MUTANT OF RICE BGLU1, A PLANT EXOGLUCANASE/BETA-GLUCOSIDASE
Descriptor:Beta-glucosidase, ZINC ION, SULFATE ION, ...
Authors:Chuenchor, W., Ketudat Cairns, J.R., Pengthaisong, S., Robinson, R.C., Yuvaniyama, J., Chen, C.-J.
Deposit date:2008-11-03
Release date:2009-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The structural basis of oligosaccharide binding by rice BGlu1 beta-glucosidase
J.Struct.Biol., 173, 2011
3F5J
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SEMI-ACTIVE E176Q MUTANT OF RICE BGLU1, A PLANT EXOGLUCANASE/BETA-GLUCOSIDASE
Descriptor:Beta-glucosidase, beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranose, ZINC ION, ...
Authors:Chuenchor, W., Ketudat Cairns, J.R., Pengthaisong, S., Robinson, R.C., Yuvaniyama, J., Chen, C.-J.
Deposit date:2008-11-03
Release date:2009-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The structural basis of oligosaccharide binding by rice BGlu1 beta-glucosidase
J.Struct.Biol., 173, 2011
3F5K
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SEMI-ACTIVE E176Q MUTANT OF RICE BGLU1, A PLANT EXOGLUCANASE/BETA-GLUCOSIDASE
Descriptor:Beta-glucosidase, CELLOPENTAOSE, ZINC ION, ...
Authors:Chuenchor, W., Ketudat Cairns, J.R., Pengthaisong, S., Robinson, R.C., Yuvaniyama, J., Chen, C.-J.
Deposit date:2008-11-03
Release date:2009-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structural basis of oligosaccharide binding by rice BGlu1 beta-glucosidase
J.Struct.Biol., 173, 2011
3F5L
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SEMI-ACTIVE E176Q MUTANT OF RICE BGLU1, A PLANT EXOGLUCANASE/BETA-GLUCOSIDASE
Descriptor:Beta-glucosidase, 3-O-beta-D-glucopyranosyl-beta-D-glucopyranose, ZINC ION, ...
Authors:Chuenchor, W., Ketudat Cairns, J.R., Pengthaisong, S., Robinson, R.C., Yuvaniyama, J., Chen, C.-J.
Deposit date:2008-11-04
Release date:2009-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:The structural basis of oligosaccharide binding by rice BGlu1 beta-glucosidase
J.Struct.Biol., 173, 2011
3INV
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TRYPANOSOMA CRUZI DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE COMPLEXED WITH NADPH, DUMP AND C-448 ANTIFOLATE
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, 1-[3-(2,3-dichlorophenoxy)propoxy]-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Chitnumsub, P., Yuvaniyama, J., Yuthavong, Y.
Deposit date:2009-08-13
Release date:2010-07-28
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structural basis of antifolate inhibition of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase
To be Published
3IRM
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TRYPANOSOMA CRUZI DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE COMPLEXED WITH CYCLOGUANIL
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine, PHOSPHATE ION, ...
Authors:Chitnumsub, P., Yuvaniyama, J., Yuthavong, Y.
Deposit date:2009-08-24
Release date:2010-07-28
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of antifolate inhibition of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase
To be Published
3IRN
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TRYPANOSOMA CRUZI DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE COMPLEXED WITH NADPH AND CYCLOGUANIL
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Chitnumsub, P., Yuvaniyama, J., Yuthavong, Y.
Deposit date:2009-08-24
Release date:2010-07-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of antifolate inhibition of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase
To be Published
3IRO
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TRYPANOSOMA CRUZI DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE COMPLEXED WITH NADPH AND Q-8 ANTIFOLATE
Descriptor:Bifunctional dihydrofolate reductase-thymidylate synthase, 5-[3-(3-fluorophenoxy)propoxy]quinazoline-2,4-diamine, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Chitnumsub, P., Yuvaniyama, J., Yuthavong, Y.
Deposit date:2009-08-24
Release date:2010-07-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of antifolate inhibition of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase
To be Published
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