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462D
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CRYSTAL STRUCTURE OF THE HIV-1 GENOMIC RNA DIMERIZATION INITIATION SITE
Descriptor:RNA (5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G) -3'), MAGNESIUM ION
Authors:Ennifar, E., Yusupov, M., Walter, P., Marquet, R., Ehresmann, C., Ehresmann, B., Dumas, P.
Deposit date:1999-03-18
Release date:1999-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of the dimerization initiation site of genomic HIV-1 RNA reveals an extended duplex with two adenine bulges.
Structure Fold.Des., 7, 1999
1Y99
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HIV-1 SUBTYPE A DIS RNA DUPLEX
Descriptor:5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', MAGNESIUM ION
Authors:Ennifar, E., Yusupov, M., Walter, P., Marquet, R., Ehresmann, B., Ehresmann, C., Dumas, P.
Deposit date:2004-12-15
Release date:2004-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of the dimerization initiation site of genomic HIV-1 RNA reveals an extended duplex with two adenine bulges
Structure Fold.Des., 7, 1999
4U4R
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CRYSTAL STRUCTURE OF LACTIMIDOMYCIN BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U3U
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CRYSTAL STRUCTURE OF CYCLOHEXIMIDE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-22
Release date:2014-10-22
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4WSD
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COMPLEX OF 70S RIBOSOME WITH TRNA-PHE AND MRNA WITH C-A MISMATCH IN THE SECOND POSITION IN THE A-SITE AND WITH ANTIBIOTIC PAROMOMYCIN.
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2014-10-27
Release date:2015-06-10
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
5E81
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STRUCTURE OF T. THERMOPHILUS 70S RIBOSOME COMPLEX WITH MRNA AND TRNALYS IN THE A-SITE WITH WOBBLE PAIR
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Khusainov, I., Yusupov, M., Yusupova, G.
Deposit date:2015-10-13
Release date:2016-01-27
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Nat Commun, 7, 2016
5NDK
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE TC007 CO-CRYSTALLIZED WITH 70S RIBOSOME FROM THERMUS THERMOPHILUS, THREE TRNAS AND MRNA
Descriptor:16S ribosomal RNA, 50S ribosomal protein L18, 50S ribosomal protein L23, ...
Authors:Prokhorova, I., Djumagulov, M., Urzhumtsev, A., Yusupov, M., Yusupova, G.
Deposit date:2017-03-08
Release date:2017-12-13
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5IBB
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STRUCTURE OF T. THERMOPHILUS 70S RIBOSOME COMPLEX WITH MRNA, TRNAFMET AND COGNATE TRNAVAL IN THE A-SITE
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2016-02-22
Release date:2016-05-25
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix.
Nucleic Acids Res., 44, 2016
6GSJ
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STRUCTURE OF T. THERMOPHILUS 70S RIBOSOME COMPLEX WITH MRNA, TRNAFMET AND COGNATE TRNATHR IN THE A-SITE
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Yusupov, M., Yusupova, G.
Deposit date:2018-06-14
Release date:2018-07-04
Last modified:2018-09-05
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria.
Nucleic Acids Res., 46, 2018
5IB7
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STRUCTURE OF T. THERMOPHILUS 70S RIBOSOME COMPLEX WITH MRNA, TRNAFMET, NEAR-COGNATE TRNALYS WITH U-G MISMATCH IN THE A-SITE AND ANTIBIOTIC PAROMOMYCIN
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2016-02-22
Release date:2016-05-25
Last modified:2016-08-10
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix.
Nucleic Acids Res., 44, 2016
4U3M
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CRYSTAL STRUCTURE OF ANISOMYCIN BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S rRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-22
Release date:2014-10-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U4Q
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CRYSTAL STRUCTURE OF HOMOHARRINGTONINE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U4U
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CRYSTAL STRUCTURE OF LYCORINE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U52
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CRYSTAL STRUCTURE OF NAGILACTONE C BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4V88
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THE STRUCTURE OF THE EUKARYOTIC RIBOSOME AT 3.0 A RESOLUTION.
Descriptor:18S RIBOSOMAL RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Ben-Shem, A., Garreau de Loubresse, N., Melnikov, S., Jenner, L., Yusupova, G., Yusupov, M.
Deposit date:2011-10-11
Release date:2014-07-09
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of the eukaryotic ribosome at 3.0 angstrom resolution.
Science, 334, 2011
4V8B
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CRYSTAL STRUCTURE ANALYSIS OF RIBOSOMAL DECODING (NEAR-COGNATE TRNA-LEU COMPLEX).
Descriptor:16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Jenner, L., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2011-12-06
Release date:2014-07-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
4V8D
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STRUCTURE ANALYSIS OF RIBOSOMAL DECODING (COGNATE TRNA-TYR COMPLEX).
Descriptor:16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Jenner, L., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2011-12-07
Release date:2014-07-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
5TBW
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CRYSTAL STRUCTURE OF CHLOROLISSOCLIMIDE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Konst, Z.A., Szklarski, A.R., Pellegrino, S., Michalak, S.E., Meyer, M., Zanette, C., Cencic, R., Nam, S., Horne, D.A., Pelletier, J., Mobley, D.L., Yusupova, G., Yusupov, M., Vanderwal, C.D.
Deposit date:2016-09-13
Release date:2017-07-26
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides.
Nat Chem, 9, 2017
4WR6
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COMPLEX OF 70S RIBOSOME WITH TRNA-TYR AND MRNA WITH A-A MISMATCH IN THE FIRST POSITION IN THE A-SITE.
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2014-10-23
Release date:2015-06-10
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WRA
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COMPLEX OF 70S RIBOSOME WITH TRNA-TYR AND MRNA WITH A-A MISMATCH IN THE FIRST POSITION IN THE A-SITE AND WITH ANTIBIOTIC PAROMOMYCIN.
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2014-10-23
Release date:2015-06-10
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WRO
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COMPLEX OF 70S RIBOSOME WITH TRNA-PHE AND MRNA WITH C-A MISMATCH IN THE SECOND POSITION IN THE A-SITE
Descriptor:16S ribosomal RNA, tRNA-Phe, tRNA-fMet, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2014-10-24
Release date:2015-06-10
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WT1
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COMPLEX OF 70S RIBOSOME WITH TRNA-PHE AND MRNA WITH A-A MISMATCH IN THE SECOND POSITION IN THE A-SITE
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2014-10-29
Release date:2015-06-10
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
1Y90
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HIV-1 DIS(MAL) DUPLEX MN-SOAKED
Descriptor:5'-R(*CP*(5BU)P*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', MANGANESE (II) ION
Authors:Ennifar, E., Walter, P., Dumas, P.
Deposit date:2004-12-14
Release date:2004-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:A crystallographic study of the binding of 13 metal ions to two related RNA duplexes
Nucleic Acids Res., 31, 2003
4U4N
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CRYSTAL STRUCTURE OF EDEINE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U4Z
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CRYSTAL STRUCTURE OF PHYLLANTHOSIDE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Garreau de Loubresse, N., Prokhorova, I., Yusupova, G., Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014