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5CQF
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CRYSTAL STRUCTURE OF L-LYSINE 6-MONOOXYGENASE FROM PSEUDOMONAS SYRINGAE
Descriptor:L-lysine 6-monooxygenase, IODIDE ION
Authors:Michalska, K., Bigelow, L., Jedrzejczak, R., Weerth, R.S., Cao, H., Yennamalli, R., Phillips Jr., G.N., Thomas, M.G., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2015-07-21
Release date:2015-09-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of L-lysine 6-monooxygenase from Pseudomonas syringae
To Be Published
5F4Z
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THE CRYSTAL STRUCTURE OF AN EPOXIDE HYDROLASE FROM STREPTOMYCES CARZINOSTATICUS SUBSP. NEOCARZINOSTATICUS
Descriptor:Epoxide hydrolase, GLYCEROL, ACETATE ION, ...
Authors:Tan, K., Li, H., Jedrzejczak, R., BABNIGG, G., BINGMAN, C.A., YENNAMALLI, R., LOHMAN, J., Chang, C.Y., Shen, B., PHILLIPS JR, G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2015-12-03
Release date:2016-02-17
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus
To Be Published
4HVM
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CRYSTAL STRUCTURE OF TALLYSOMYCIN BIOSYNTHESIS PROTEIN TLMII
Descriptor:TlmII, SULFATE ION
Authors:Chang, C., Bigelow, L., Bearden, J., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2012-11-06
Release date:2012-11-21
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:Crystal structure of tallysomycin biosynthesis protein TlmII
To be Published
4I19
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THE CRYSTAL STRUCTURE OF AN EPOXIDE HYDROLASE FROM STREPTOMYCES CARZINOSTATICUS SUBSP. NEOCARZINOSTATICUS.
Descriptor:Epoxide hydrolase, ACETATE ION, FORMIC ACID
Authors:Tan, K., Bigelow, L., Clancy, S., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2012-11-20
Release date:2012-12-05
Last modified:2013-01-30
Method:X-RAY DIFFRACTION (2.148 Å)
Cite:The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus.
To be Published
4I4J
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THE STRUCTURE OF SGCE10, THE ACP-POLYENE THIOESTERASE INVOLVED IN C-1027 BIOSYNTHESIS
Descriptor:ACP-polyene thioesterase, D(-)-TARTARIC ACID, 1,2-ETHANEDIOL, ...
Authors:Kim, Y., Bigelow, L., Bearden, J., Babnigg, J., Bingman, C.A., Yennamalli, R., Lohman, J., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2012-11-27
Release date:2012-12-12
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (2.784 Å)
Cite:The structure of SgcE10, the ACP-polyene thioesterase involved in C-1027 biosynthesis
To be Published
4QA9
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ENSEMBLE REFINEMENT OF AN EPOXIDE HYDROLASE FROM STREPTOMYCES CARZINOSTATICUS SUBSP. NEOCARZINOSTATICUS.
Descriptor:Epoxide hydrolase, SULFATE ION, 1,2-ETHANEDIOL
Authors:Wang, F., Tan, K., Bigelow, L., Clancy, S., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J., Ma, M., Shen, B., Joachimiak, A., Phillips Jr., G.N., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-05-02
Release date:2014-05-21
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Ensemble refinement of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus.
To be Published
4MV2
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CRYSTAL STRUCTURE OF PLU4264 PROTEIN FROM PHOTORHABDUS LUMINESCENS
Descriptor:plu4264, NICKEL (II) ION, SODIUM ION
Authors:Michalska, K., Li, H., Jedrzejczak, R., Babnigg, G., Bingman, C.A., Yennamalli, R., Weerth, S., Thomas, M.G., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2013-09-23
Release date:2013-10-02
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (1.349 Å)
Cite:Structure of a cupin protein Plu4264 from Photorhabdus luminescens subsp. laumondii TTO1 at 1.35 angstrom resolution.
Proteins, 83, 2015
4Q29
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ENSEMBLE REFINEMENT OF PLU4264 PROTEIN FROM PHOTORHABDUS LUMINESCENS
Descriptor:plu4264 protein, NICKEL (II) ION, SODIUM ION
Authors:Wang, F., Michalska, K., Li, H., Jedrzejczak, R., Babnigg, G., Bingman, C.A., Yennamalli, R., Weerth, S., Miller, M.D., Thomas, M.G., Joachimiak, A., Phillips Jr., G.N., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2014-04-07
Release date:2014-05-07
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (1.349 Å)
Cite:Structure of a cupin protein Plu4264 from Photorhabdus luminescens subsp. laumondii TTO1 at 1.35 angstrom resolution.
Proteins, 83, 2015
4HX6
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STREPTOMYCES GLOBISPORUS C-1027 NADH:FAD OXIDOREDUCTASE SGCE6
Descriptor:Oxidoreductase, SULFATE ION, ACETATE ION
Authors:Tan, K., Bigelow, L., Clancy, S., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2012-11-09
Release date:2012-11-28
Last modified:2016-12-07
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.
Biochemistry, 55, 2016
4I4K
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STREPTOMYCES GLOBISPORUS C-1027 9-MEMBERED ENEDIYNE CONSERVED PROTEIN SGCE6
Descriptor:uncharacterized protein SgcJ, CITRIC ACID, TETRAETHYLENE GLYCOL, ...
Authors:Kim, Y., Bigelow, L., Clancy, S., Babnigg, J., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2012-11-27
Release date:2012-12-12
Last modified:2016-12-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027.
J Antibiot (Tokyo), 69, 2016
4OO2
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STREPTOMYCES GLOBISPORUS C-1027 FAD DEPENDENT (S)-3-CHLORO-β-TYROSINE-S-SGCC2 C-5 HYDROXYLASE SGCC APO FORM
Descriptor:Chlorophenol-4-monooxygenase, CALCIUM ION, GLYCEROL
Authors:Cao, H., Xu, W., Bingman, C., Lohman, J.R., Yennamalli, R., Shen, B., Phillips Jr., G.N., Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-01-29
Release date:2014-02-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.
Biochemistry, 55, 2016
4OVM
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CRYSTAL STRUCTURE OF SGCJ PROTEIN FROM STREPTOMYCES CARZINOSTATICUS
Descriptor:uncharacterized protein SgcJ
Authors:Chang, C., Bigelow, L., Clancy, S., Bingman, C., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Babnigg, G., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2013-11-20
Release date:2013-12-25
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.719 Å)
Cite:Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027.
J.Antibiot., 2016
4R82
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STREPTOMYCES GLOBISPORUS C-1027 NADH:FAD OXIDOREDUCTASE SGCE6 IN COMPLEX WITH NAD AND FAD FRAGMENTS
Descriptor:Oxidoreductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, CALCIUM ION, ...
Authors:Tan, K., Bigelow, L., Clancy, S., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-08-29
Release date:2014-10-01
Last modified:2016-11-02
Method:X-RAY DIFFRACTION (1.659 Å)
Cite:Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.
Biochemistry, 55, 2016
4IAG
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CRYSTAL STRUCTURE OF ZBMA, THE ZORBAMYCIN BINDING PROTEIN FROM STREPTOMYCES FLAVOVIRIDIS
Descriptor:Zbm binding protein, 1,2-ETHANEDIOL, GLYCEROL
Authors:Cuff, M.E., Bigelow, L., Bruno, C.J.P., Clancy, S., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2012-12-06
Release date:2013-02-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892.
Biochemistry, 54, 2015
4NEO
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STRUCTURE OF BLMI, A TYPE-II ACYL-CARRIER-PROTEIN FROM STREPTOMYCES VERTICILLUS INVOLVED IN BLEOMYCIN BIOSYNTHESIS
Descriptor:Peptide synthetase NRPS type II-PCP, 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL
Authors:Cuff, M.E., Bigelow, L., Bearden, J., Babnigg, G., Bruno, C.J.P., Bingman, C., Yennamalli, R., Lohman, J., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2013-10-29
Release date:2014-01-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteins.
Proteins, 82, 2014
4NNQ
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CRYSTAL STRUCTURE OF LNMF PROTEIN FROM STREPTOMYCES AMPHIBIOSPORUS
Descriptor:Putative enoyl-CoA hydratase, SULFATE ION
Authors:Michalska, K., Bigelow, L., Endres, M., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2013-11-18
Release date:2014-01-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:

4OPE
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STREPTOMCYES ALBUS JA3453 OXAZOLOMYCIN KETOSYNTHASE DOMAIN OZMH KS7
Descriptor:NRPS/PKS, NITRATE ION
Authors:Osipiuk, J., Mack, J., Endres, M., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-02-05
Release date:2014-02-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4OPF
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STREPTOMCYES ALBUS JA3453 OXAZOLOMYCIN KETOSYNTHASE DOMAIN OZMH KS8
Descriptor:NRPS/PKS
Authors:Osipiuk, J., Bigelow, L., Endres, M., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-02-05
Release date:2014-02-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4OQJ
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STREPTOMCYES ALBUS JA3453 OXAZOLOMYCIN KETOSYNTHASE DOMAIN OZMQ KS1
Descriptor:PKS, POTASSIUM ION, PHOSPHATE ION, ...
Authors:Nocek, B., Mack, J., Endras, M., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-02-09
Release date:2014-03-19
Last modified:2016-11-02
Method:X-RAY DIFFRACTION (1.904 Å)
Cite:Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4QYR
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STREPTOMYCES PLATENSIS ISOMIGRASTATIN KETOSYNTHASE DOMAIN MGSE KS3
Descriptor:AT-less polyketide synthase, GLYCEROL, ACETIC ACID, ...
Authors:Kim, Y., Li, H., Endres, M., Babnigg, J., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-07-25
Release date:2014-08-20
Last modified:2016-12-07
Method:X-RAY DIFFRACTION (2.902 Å)
Cite:Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4TKT
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STREPTOMYCES PLATENSIS ISOMIGRASTATIN KETOSYNTHASE DOMAIN MGSF KS6
Descriptor:AT-less polyketide synthase, CHLORIDE ION, SULFATE ION, ...
Authors:Chang, C., Li, H., Endres, M., Bingman, C., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-05-27
Release date:2014-06-11
Last modified:2016-11-02
Method:X-RAY DIFFRACTION (2.4289 Å)
Cite:Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WKY
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STREPTOMCYES ALBUS JA3453 OXAZOLOMYCIN KETOSYNTHASE DOMAIN OZMN KS2
Descriptor:Beta-ketoacyl synthase, SULFATE ION, GLYCEROL, ...
Authors:Cuff, M.E., Mack, J.C., Endres, M., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-10-03
Release date:2014-10-29
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZDN
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STREPTOMYCES PLATENSIS ISOMIGRASTATIN KETOSYNTHASE DOMAIN MGSF KS4
Descriptor:AT-less polyketide synthase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION
Authors:Chang, C., Li, H., Endres, M., Bingman, C., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2015-04-17
Release date:2015-05-13
Last modified:2016-11-02
Method:X-RAY DIFFRACTION (2.509 Å)
Cite:Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015