4I4J
The structure of SgcE10, the ACP-polyene thioesterase involved in C-1027 biosynthesis
Summary for 4I4J
Entry DOI | 10.2210/pdb4i4j/pdb |
Descriptor | ACP-polyene thioesterase, D(-)-TARTARIC ACID, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | structural genomics, psi-biology, midwest center for structural genomics, mcsg, enzyme discovery for natural product biosynthesis, natpro, alpha-beta fold, hot-dog fold, esterase, hydrolase |
Biological source | Streptomyces globisporus |
Total number of polymer chains | 8 |
Total formula weight | 145856.66 |
Authors | Kim, Y.,Bigelow, L.,Bearden, J.,Babnigg, J.,Bingman, C.A.,Yennamalli, R.,Lohman, J.,Ma, M.,Shen, B.,Phillips Jr., G.N.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2012-11-27, release date: 2012-12-12, Last modification date: 2022-05-04) |
Primary citation | Annaval, T.,Rudolf, J.D.,Chang, C.Y.,Lohman, J.R.,Kim, Y.,Bigelow, L.,Jedrzejczak, R.,Babnigg, G.,Joachimiak, A.,Phillips Jr., G.N.,Shen, B. Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis. Acs Omega, 2:5159-5169, 2017 Cited by PubMed: 28884166DOI: 10.1021/acsomega.7b00933 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.784 Å) |
Structure validation
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