Author results

1NAV
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THYROID RECEPTOR ALPHA IN COMPLEX WITH AN AGONIST SELECTIVE FOR THYROID RECEPTOR BETA1
Descriptor:hormone receptor alpha 1, THRA1, SULFATE ION, ...
Authors:Ye, L., Li, Y.L., Mellstrom, K., Mellin, C., Bladh, L.G., Koehler, K., Garg, N., Garcia Collazo, A.M., Litten, C., Husman, B., Persson, K., Ljunggren, J., Grover, G., Sleph, P.G., George, R., Malm, J.
Deposit date:2002-11-29
Release date:2003-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1.
J.Med.Chem., 46, 2003
1NAX
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THYROID RECEPTOR BETA1 IN COMPLEX WITH A BETA-SELECTIVE LIGAND
Descriptor:Thyroid hormone receptor beta-1, {3,5-DICHLORO-4-[4-HYDROXY-3-(PROPAN-2-YL)PHENOXY]PHENYL}ACETIC ACID
Authors:Ye, L., Li, Y.L., Mellstrom, K., Mellin, C., Bladh, L.G., Koehler, K., Garg, N., Garcia Collazo, A.M., Litten, C., Husman, B., Persson, K., Ljunggren, J., Grover, G., Sleph, P.G., George, R., Malm, J.
Deposit date:2002-11-29
Release date:2003-06-17
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1.
J.Med.Chem., 46, 2003
2KLN
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SOLUTION STRUCTURE OF STAS DOMAIN OF RV1739C FROM M. TUBERCULOSIS
Descriptor:PROBABLE SULPHATE-TRANSPORT TRANSMEMBRANE PROTEIN, COG0659
Authors:Sharma, A.K., Ye, L., Zolotarev, A.S., Alper, S.L., Rigby, A.C.
Deposit date:2009-07-06
Release date:2010-12-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the Guanine Nucleotide-binding STAS Domain of SLC26-related SulP Protein Rv1739c from Mycobacterium tuberculosis.
J.Biol.Chem., 286, 2011
5V56
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2.9A XFEL STRUCTURE OF THE MULTI-DOMAIN HUMAN SMOOTHENED RECEPTOR (WITH E194M MUTATION) IN COMPLEX WITH TC114
Descriptor:Smoothened homolog,Flavodoxin,Smoothened homolog, N-methyl-N-[1-[4-(2-methylpyrazol-3-yl)phthalazin-1-yl]piperidin-4-yl]-4-nitro-2-(trifluoromethyl)benzamide, FLAVIN MONONUCLEOTIDE, ...
Authors:Zhang, X., Zhao, F., Wu, Y., Yang, J., Han, G.W., Zhao, S., Ishchenko, A., Ye, L., Lin, X., Ding, K., Dharmarajan, V., Griffin, P.R., Gati, C., Nelson, G., Hunter, M.S., Hanson, M.A., Cherezov, V., Stevens, R.C., Tan, W., Tao, H., Xu, F.
Deposit date:2017-03-13
Release date:2017-05-24
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand.
Nat Commun, 8, 2017
5V57
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3.0A SYN STRUCTURE OF THE MULTI-DOMAIN HUMAN SMOOTHENED RECEPTOR IN COMPLEX WITH TC114
Descriptor:Smoothened homolog,Flavodoxin,Smoothened homolog, N-methyl-N-[1-[4-(2-methylpyrazol-3-yl)phthalazin-1-yl]piperidin-4-yl]-4-nitro-2-(trifluoromethyl)benzamide, FLAVIN MONONUCLEOTIDE, ...
Authors:Zhang, X., Zhao, F., Wu, Y., Yang, J., Han, G.W., Zhao, S., Ishchenko, A., Ye, L., Lin, X., Ding, K., Dharmarajan, V., Griffin, P.R., Gati, C., Nelson, G., Hunter, M.S., Hanson, M.A., Cherezov, V., Stevens, R.C., Tan, W., Tao, H., Xu, F.
Deposit date:2017-03-13
Release date:2017-05-24
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand.
Nat Commun, 8, 2017
5VEW
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STRUCTURE OF THE HUMAN GLP-1 RECEPTOR COMPLEX WITH PF-06372222
Descriptor:Glucagon-like peptide 1 receptor,Endolysin chimera, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ...
Authors:Song, G., Yang, D., Wang, Y., Graaf, C.D., Zhou, Q., Jiang, S., Liu, K., Cai, X., Dai, A., Lin, G., Liu, D., Wu, F., Wu, Y., Zhao, S., Ye, L., Han, G.W., Lau, J., Wu, B., Hanson, M.A., Liu, Z.-J., Wang, M.-W., Stevens, R.C.
Deposit date:2017-04-05
Release date:2017-05-24
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators.
Nature, 546, 2017
5VEX
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STRUCTURE OF THE HUMAN GLP-1 RECEPTOR COMPLEX WITH NNC0640
Descriptor:Glucagon-like peptide 1 receptor, Endolysin chimera, 4-{[(4-cyclohexylphenyl){[3-(methylsulfonyl)phenyl]carbamoyl}amino]methyl}-N-(1H-tetrazol-5-yl)benzamide
Authors:Song, G., Yang, D., Wang, Y., Graaf, C.D., Zhou, Q., Jiang, S., Liu, K., Cai, X., Dai, A., Lin, G., Liu, D., Wu, F., Wu, Y., Zhao, S., Ye, L., Han, G.W., Lau, J., Wu, B., Hanson, M.A., Liu, Z.-J., Wang, M.-W., Stevens, R.C.
Deposit date:2017-04-05
Release date:2017-05-17
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators.
Nature, 546, 2017
6A50
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STRUCTURE OF BENZOYLFORMATE DECARBOXYLASES IN COMPLEX WITH COFACTOR TPP
Descriptor:benzoylformate decarboxylases, MAGNESIUM ION, THIAMINE DIPHOSPHATE
Authors:Guo, Y., Wang, S., Nie, Y., Li, S.
Deposit date:2018-06-21
Release date:2019-02-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Synthetic Pathway for Acetyl-Coenzyme A Biosynthesis
Nat Commun, 2019
5K3A
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CRYSTAL STRUCTURE OF THE FLUOROACETATE DEHALOGENASE RPA1163 - HIS280ASN/FLUOROACETATE - COCRYSTALLIZED - BOTH PROTOMERS REACTED WITH LIGAND
Descriptor:Fluoroacetate dehalogenase, CHLORIDE ION
Authors:Mehrabi, P., Kim, T.H., Prosser, S.R., Pai, E.F.
Deposit date:2016-05-19
Release date:2017-02-01
Method:X-RAY DIFFRACTION (1.511 Å)
Cite:The role of dimer asymmetry and protomer dynamics in enzyme catalysis.
Science, 355, 2017
5K3B
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CRYSTAL STRUCTURE OF THE FLUOROACETATE DEHALOGENASE RPA1163 - ASP110ASN/CHLOROACETATE - COCRYSTALLIZED
Descriptor:Fluoroacetate dehalogenase, CHLORIDE ION, chloroacetic acid
Authors:Mehrabi, P., Kim, T.H., Prosser, S.R., Pai, E.F.
Deposit date:2016-05-19
Release date:2017-02-01
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:The role of dimer asymmetry and protomer dynamics in enzyme catalysis.
Science, 355, 2017
5K3C
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CRYSTAL STRUCTURE OF THE FLUOROACETATE DEHALOGENASE RPA1163 - WT/5-FLUOROTRYPTOPHAN
Descriptor:Fluoroacetate dehalogenase, CHLORIDE ION
Authors:Mehrabi, P., Kim, T.H., Prosser, S.R., Pai, E.F.
Deposit date:2016-05-19
Release date:2017-02-01
Method:X-RAY DIFFRACTION (1.541 Å)
Cite:The role of dimer asymmetry and protomer dynamics in enzyme catalysis.
Science, 355, 2017
5K3D
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CRYSTAL STRUCTURE OF THE FLUOROACETATE DEHALOGENASE RPA1163 - WT/APO - NO HALIDE
Descriptor:Fluoroacetate dehalogenase
Authors:Mehrabi, P., Kim, T.H., Prosser, S.R., Pai, E.F.
Deposit date:2016-05-19
Release date:2017-02-01
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The role of dimer asymmetry and protomer dynamics in enzyme catalysis.
Science, 355, 2017
5K3E
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CRYSTAL STRUCTURE OF THE FLUOROACETATE DEHALOGENASE RPA1163 - ASP110ASN/GLYCOLATE - COCRYSTALLIZED
Descriptor:Fluoroacetate dehalogenase, GLYCOLIC ACID, CHLORIDE ION
Authors:Mehrabi, P., Kim, T.H., Prosser, S.R., Pai, E.F.
Deposit date:2016-05-19
Release date:2017-02-01
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:The role of dimer asymmetry and protomer dynamics in enzyme catalysis.
Science, 355, 2017
5K3F
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CRYSTAL STRUCTURE OF THE FLUOROACETATE DEHALOGENASE RPA1163 - HIS280ASN/FLUOROACETATE - COCRYSTALLIZED - SINGLE PROTOMER REACTED WITH LIGAND
Descriptor:Fluoroacetate dehalogenase, CHLORIDE ION
Authors:Mehrabi, P., Kim, T.H., Prosser, S.R., Pai, E.F.
Deposit date:2016-05-19
Release date:2017-02-01
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:The role of dimer asymmetry and protomer dynamics in enzyme catalysis.
Science, 355, 2017
5SWN
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CRYSTAL STRUCTURE OF THE FLUOROACETATE DEHALOGENASE RPA1163 - ASP110ASN/FLUOROACETATE - COCRYSTALLIZED
Descriptor:Fluoroacetate dehalogenase, fluoroacetic acid, CHLORIDE ION
Authors:Mehrabi, P., Kim, T.H., Prosser, S.R., Pai, E.F.
Deposit date:2016-08-08
Release date:2017-02-01
Method:X-RAY DIFFRACTION (1.541 Å)
Cite:The role of dimer asymmetry and protomer dynamics in enzyme catalysis.
Science, 355, 2017
5T4T
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CRYSTAL STRUCTURE OF THE FLUOROACETATE DEHALOGENASE RPA1163 - ASP110ASN - APO NO HALIDE
Descriptor:Fluoroacetate dehalogenase, ACETATE ION
Authors:Mehrabi, P., Kim, T.H., Prosser, S.R., Pai, E.F.
Deposit date:2016-08-30
Release date:2017-02-01
Method:X-RAY DIFFRACTION (1.511 Å)
Cite:The role of dimer asymmetry and protomer dynamics in enzyme catalysis.
Science, 355, 2017