7MW5
Structure of the SARS-CoV-2 Spike trimer with one RBD down in complex with the Fab fragment of human neutralizing antibody clone 2
Summary for 7MW5
Entry DOI | 10.2210/pdb7mw5/pdb |
EMDB information | 24063 |
Descriptor | Fab of antibody clone 2, light chain, Fab of antibody clone 2, heavy chain, Spike glycoprotein, ... (5 entities in total) |
Functional Keywords | viral protein, antibody, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 9 |
Total formula weight | 614215.90 |
Authors | |
Primary citation | Peng, L.,Hu, Y.,Mankowski, M.C.,Ren, P.,Chen, R.E.,Wei, J.,Zhao, M.,Li, T.,Tripler, T.,Ye, L.,Chow, R.D.,Fang, Z.,Wu, C.,Dong, M.B.,Cook, M.,Wang, G.,Clark, P.,Nelson, B.,Klein, D.,Sutton, R.,Diamond, M.S.,Wilen, C.B.,Xiong, Y.,Chen, S. Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617. Nat Commun, 13:1638-1638, 2022 Cited by PubMed: 35347138DOI: 10.1038/s41467-022-29288-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.42 Å) |
Structure validation
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