1NAV
Thyroid Receptor Alpha in complex with an agonist selective for Thyroid Receptor Beta1
Summary for 1NAV
Entry DOI | 10.2210/pdb1nav/pdb |
Related | 1NAX |
Descriptor | hormone receptor alpha 1, THRA1, SULFATE ION, {3,5-DICHLORO-4-[4-HYDROXY-3-(PROPAN-2-YL)PHENOXY]PHENYL}ACETIC ACID, ... (4 entities in total) |
Functional Keywords | nuclear receptor, thyroid receptor, ligand, complex, membrane protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P10827 |
Total number of polymer chains | 1 |
Total formula weight | 30440.92 |
Authors | Ye, L.,Li, Y.L.,Mellstrom, K.,Mellin, C.,Bladh, L.G.,Koehler, K.,Garg, N.,Garcia Collazo, A.M.,Litten, C.,Husman, B.,Persson, K.,Ljunggren, J.,Grover, G.,Sleph, P.G.,George, R.,Malm, J. (deposition date: 2002-11-29, release date: 2003-06-17, Last modification date: 2024-02-14) |
Primary citation | Ye, L.,Li, Y.L.,Mellstrom, K.,Mellin, C.,Bladh, L.G.,Koehler, K.,Garg, N.,Garcia Collazo, A.M.,Litten, C.,Husman, B.,Persson, K.,Ljunggren, J.,Grover, G.,Sleph, P.G.,George, R.,Malm, J. Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1. J.Med.Chem., 46:1580-1588, 2003 PubMed: 12699376 DOI: 10.1021/jm021080f PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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