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2L7U
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STRUCTURE OF CEL-PEP-RAGE V DOMAIN COMPLEX
Descriptor:Advanced glycosylation end product-specific receptor, Serum albumin peptide
Authors:Xue, J., Rai, V., Schmidt, A., Frolov, S., Reverdatto, S., Singer, D., Chabierski, S., Xie, J., Burz, D., Shekhtman, A., Hoffman, R.
Deposit date:2010-12-23
Release date:2011-05-18
Last modified:2018-05-30
Method:SOLUTION NMR
Cite:Advanced glycation end product recognition by the receptor for AGEs.
Structure, 19, 2011
5XXE
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CRYSTAL STRUCTURE OF POZ1 AND TPZ1
Descriptor:Protection of telomeres protein poz1, Protection of telomeres protein tpz1, SULFATE ION, ...
Authors:Xue, J., Chen, H., Wu, J., Lei, M.
Deposit date:2017-07-03
Release date:2017-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the fission yeast S. pombe telomeric Tpz1-Poz1-Rap1 complex.
Cell Res., 27, 2017
5XXF
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CRYSTAL STRUCTURE OF POZ1, TPZ1 AND RAP1
Descriptor:Protection of telomeres protein poz1, Protection of telomeres protein tpz1, Rap1, ...
Authors:Xue, J., Chen, H., Wu, J., Lei, M.
Deposit date:2017-07-03
Release date:2017-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the fission yeast S. pombe telomeric Tpz1-Poz1-Rap1 complex.
Cell Res., 27, 2017
4GAE
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CRYSTAL STRUCTURE OF PLASMODIUM DXR IN COMPLEX WITH A PYRIDINE-CONTAINING INHIBITOR
Descriptor:1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplast, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Diao, J., Xue, J., Cai, G., Deng, L., Song, Y.
Deposit date:2012-07-25
Release date:2013-02-06
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Antimalarial and Structural Studies of Pyridine-containing Inhibitors of 1-Deoxyxylulose-5-phosphate Reductoisomerase.
ACS Med Chem Lett, 4, 2013
2MOV
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RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS (RAGE) SPECIFICALLY RECOGNIZES METHYLGLYOXAL DERIVED AGES.
Descriptor:Advanced glycosylation end product-specific receptor, N~5~-[(5R)-5-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl]-L-ornithine
Authors:Shekhtman, A., Xue, J., Ray, R., Singer, D., Bohme, D., Burz, D.S., Rai, V., Hoffman, R.
Deposit date:2014-05-05
Release date:2014-06-25
Method:SOLUTION NMR
Cite:The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs.
Biochemistry, 53, 2014
5Y58
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CRYSTAL STRUCTURE OF KU70/80 AND TLC1
Descriptor:ATP-dependent DNA helicase II subunit 1, ATP-dependent DNA helicase II subunit 2, TLC1
Authors:Chen, H., Xue, J., Wu, J., Lei, M.
Deposit date:2017-08-08
Release date:2017-12-20
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Insights into Yeast Telomerase Recruitment to Telomeres
Cell, 172, 2018
5Y59
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CRYSTAL STRUCTURE OF KU80 AND SIR4
Descriptor:ATP-dependent DNA helicase II subunit 2, Sir4p, SULFATE ION
Authors:Chen, H., Xue, J., Wu, J., Lei, M.
Deposit date:2017-08-08
Release date:2017-12-20
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Structural Insights into Yeast Telomerase Recruitment to Telomeres
Cell, 172, 2018
5Y5A
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CRYSTAL STRUCTURE OF EST1 AND CDC13
Descriptor:KLLA0F20702p, KLLA0F20922p
Authors:Chen, H., Xue, J., Wu, J., Lei, M.
Deposit date:2017-08-08
Release date:2017-12-20
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:Structural Insights into Yeast Telomerase Recruitment to Telomeres
Cell, 172, 2018
2YPJ
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NON-CATALYTIC CARBOHYDRATE BINDING MODULE CBM65B
Descriptor:ENDOGLUCANASE CEL5A, BETA-D-GLUCOSE, XYLOPYRANOSE
Authors:Luis, A.S., Venditto, I., Prates, J.A.M., Ferreira, L.M.A., Temple, M.J., Rogowski, A., Basle, A., Xue, J., Knox, J.P., Gilbert, H.J., Fontes, C.M.G.A., Najmudin, S.
Deposit date:2012-10-30
Release date:2012-12-19
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Understanding How Non-Catalytic Carbohydrate Binding Modules Can Display Specificity for Xyloglucan
J.Biol.Chem., 288, 2013
4O26
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CRYSTAL STRUCTURE OF THE TRBD DOMAIN OF TERT AND THE CR4/5 OF TR
Descriptor:Telomerase reverse transcriptase, Telomerase TR, SULFATE ION
Authors:Huang, J., Wu, J., Lei, M.
Deposit date:2013-12-16
Release date:2014-05-07
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Structural basis for protein-RNA recognition in telomerase.
Nat.Struct.Mol.Biol., 21, 2014
3EB7
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CRYSTAL STRUCTURE OF INSECTICIDAL DELTA-ENDOTOXIN CRY8EA1 FROM BACILLUS THURINGIENSIS AT 2.2 ANGSTROMS RESOLUTION
Descriptor:Insecticidal Delta-Endotoxin Cry8Ea1, SULFATE ION, ACETATE ION
Authors:Guo, S., Ye, S., Song, F., Zhang, J., Wei, L., Shu, C.L.
Deposit date:2008-08-27
Release date:2008-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of Bacillus thuringiensis Cry8Ea1: An insecticidal toxin toxic to underground pests, the larvae of Holotrichia parallela.
J.Struct.Biol., 168, 2009
6AC0
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CRYSTAL STRUCTURE OF TRADD DEATH DOMAIN GLCNACYLATED BY EPEC EFFECTOR NLEB
Descriptor:Tumor necrosis factor receptor type 1-associated DEATH domain protein, N-ACETYL-D-GLUCOSAMINE
Authors:Ding, J., Shao, F.
Deposit date:2018-07-24
Release date:2019-05-01
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.
Mol.Cell, 74, 2019
6AC5
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CRYSTAL STRUCTURE OF RIPK1 DEATH DOMAIN GLCNACYLATED BY EPEC EFFECTOR NLEB
Descriptor:Receptor-interacting serine/threonine-protein kinase 1, N-ACETYL-D-GLUCOSAMINE, SULFATE ION
Authors:Ding, J., Shao, F.
Deposit date:2018-07-25
Release date:2019-05-01
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.
Mol.Cell, 74, 2019
6ACI
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CRYSTAL STRUCTURE OF EPEC EFFECTOR NLEB IN COMPLEX WITH FADD DEATH DOMAIN
Descriptor:T3SS secreted effector NleB homolog, FAS-associated death domain protein, URIDINE-5'-DIPHOSPHATE, ...
Authors:Ding, J., Shao, F.
Deposit date:2018-07-26
Release date:2019-05-01
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.
Mol.Cell, 74, 2019
4BA6
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HIGH RESOLUTION STRUCTURE OF THE C-TERMINAL FAMILY 65 CARBOHYDRATE BINDING MODULE (CBM65B) OF ENDOGLUCANASE CEL5A FROM EUBACTERIUM CELLULOSOLVENS
Descriptor:Endoglucanase cel5A, GLYCEROL
Authors:Venditto, I., Luis, A.S., Basle, A., Temple, M., Ferreira, L.M.A., Fontes, C.M.G.A., Gilbert, H.J., Najmudin, S.
Deposit date:2012-09-11
Release date:2012-12-19
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Understanding how noncatalytic carbohydrate binding modules can display specificity for xyloglucan.
J. Biol. Chem., 288, 2013
4QVX
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DISCOVERY OF A POTENT AND SELECTIVE BCL-XL INHIBITOR THAT DEMONSTRATES THROMBOCYTOPENIA AND INHIBITS TUMOR GROWTH IN VIVO
Descriptor:Bcl-2-like protein 1, 2-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl]-5-(3-{4-[3-(dimethylamino)prop-1-yn-1-yl]-2-fluorophenoxy}propyl)-1,3-thiazole-4-carboxylic acid
Authors:Park, C.H.
Deposit date:2014-07-16
Release date:2015-07-22
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity.
ACS MED.CHEM.LETT., 5, 2014
5VKC
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CRYSTAL STRUCTURE OF MCL-1 IN COMPLEX WITH A BIM COMPETITIVE INHIBITOR
Descriptor:Induced myeloid leukemia cell differentiation protein Mcl-1, 7-(3-{[4-(4-acetylpiperazin-1-yl)phenoxy]methyl}-1,5-dimethyl-1H-pyrazol-4-yl)-3-{3-[(naphthalen-1-yl)oxy]propyl}-1-[(pyridin-3-yl)methyl]-1H-indole-2-carboxylic acid, ZINC ION
Authors:Judge, R.A., Souers, A.J.
Deposit date:2017-04-21
Release date:2017-05-03
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity.
J. Med. Chem., 58, 2015
5XYF
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CRYSTAL STRUCTURE OF THE HUMAN TIN2-TPP1-TRF2 TELOMERIC COMPLEX
Descriptor:TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 2, Adrenocortical dysplasia protein homolog
Authors:Hu, C., Chen, Y.
Deposit date:2017-07-07
Release date:2017-12-13
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex.
Cell Res., 27, 2017
6B4L
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CRYSTAL STRUCTURE OF MCL-1 IN COMPLEX WITH A BIM COMPETITIVE INHIBITOR
Descriptor:Induced myeloid leukemia cell differentiation protein Mcl-1, 3-{3-[(naphthalen-1-yl)oxy]propyl}-1H-indole-2-carboxylic acid
Authors:Judge, R.A., Souers, A.J.
Deposit date:2017-09-26
Release date:2017-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity.
J. Med. Chem., 58, 2015
6B4U
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CRYSTAL STRUCTURE OF MCL-1 IN COMPLEX WITH A BIM COMPETITIVE INHIBITOR
Descriptor:Induced myeloid leukemia cell differentiation protein Mcl-1, 7-(2-methylphenyl)-1-[2-(morpholin-4-yl)ethyl]-3-{3-[(naphthalen-1-yl)oxy]propyl}-1H-indole-2-carboxylic acid
Authors:Judge, R.A., Souers, A.J.
Deposit date:2017-09-27
Release date:2017-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity.
J. Med. Chem., 58, 2015
6E66
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CRYSTAL STRUCTURE OF BACTERIAL N-ACETYLGLUCOSAMINE TRANSFERASE NLEB
Descriptor:NleB, 1,2-ETHANEDIOL
Authors:Yao, Q., Zheng, Y.Q., Shao, F.
Deposit date:2018-07-23
Release date:2019-06-05
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.
Mol.Cell, 74, 2019
4AEK
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STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF A NOVEL CARBOHYDRATE BINDING MODULE OF ENDOGLUCANASE CEL5A FROM EUBACTERIUM CELLULOSOLVENS
Descriptor:ENDOGLUCANASE CEL5A
Authors:Luis, A.S., Venditto, I., Prates, J.A.M., Ferreira, L.M.A., Gilbert, H.J., Fontes, C.M.G.A., Najmudin, S.
Deposit date:2012-01-11
Release date:2013-01-16
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Understanding How Non-Catalytic Carbohydrate Binding Modules Can Display Specificity for Xyloglucan.
J.Biol.Chem., 288, 2013
4AEM
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STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF A NOVEL CARBOHYDRATE BINDING MODULE OF ENDOGLUCANASE CEL5A FROM EUBACTERIUM CELLULOSOLVENS
Descriptor:ENDOGLUCANASE CEL5A
Authors:Luis, A.S., Venditto, I., Prates, J.A.M., Ferreira, L.M.A., Gilbert, H.J., Fontes, C.M.G.A., Najmudin, S.
Deposit date:2012-01-11
Release date:2013-01-23
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Understanding How Non-Catalytic Carbohydrate Binding Modules Can Display Specificity for Xyloglucan
J.Biol.Chem., 288, 2013
4AFD
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STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF A NOVEL CARBOHYDRATE BINDING MODULE OF ENDOGLUCANASE CEL5A FROM EUBACTERIUM CELLULOSOLVENS WITH A PARTIALLY BOUND CELLOTETRAOSE MOEITY.
Descriptor:ENDOGLUCANASE CEL5A, BETA-D-GLUCOSE
Authors:Luis, A.S., Venditto, I., Prates, J.A.M., Ferreira, L.M.A., Gilbert, H.J., Fontes, C.M.G.A., Najmudin, S.
Deposit date:2012-01-18
Release date:2012-12-26
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Understanding How Noncatalytic Carbohydrate Binding Modules Can Display Specificity for Xyloglucan.
J.Biol.Chem., 288, 2013
4AFM
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STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF A NOVEL CARBOHYDRATE BINDING MODULE OF ENDOGLUCANASE CEL5A FROM EUBACTERIUM CELLULOSOLVENS.
Descriptor:ENDOGLUCANASE CEL5A, GLYCEROL, ACETATE ION
Authors:Luis, A.S., Venditto, I., Prates, J.A.M., Ferreira, L.M.A., Gilbert, H.J., Fontes, C.M.G.A., Najmudin, S.
Deposit date:2012-01-19
Release date:2012-12-19
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Understanding How Non-Catalytic Carbohydrate Binding Modules Can Display Specificity for Xyloglucan.
J.Biol.Chem., 288, 2013
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