7LFX

Cryo-EM structure of human cGMP-bound open CNGA1 channel in Na+/Ca2+

Summary for 7LFX

• Entry DOI: 10.2210/pdb7lfx/pdb
• EMDB information: 23308
• Descriptor: cGMP-gated cation channel alpha-1, CYCLIC GUANOSINE MONOPHOSPHATE, CALCIUM ION (3 entities in total)
• Functional Keywords: alpha-helical, membrane protein, ion channel
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 260062.71

Authors

Xue, J.,Han, Y.,Jiang, Y. (deposition date: 2021-01-19, release date: 2021-03-10, Last modification date: 2024-03-06)

• Primary citation: Xue, J.,Han, Y.,Zeng, W.,Wang, Y.,Jiang, Y.; Structural mechanisms of gating and selectivity of human rod CNGA1 channel.; Neuron, 109:1302-1313.e4, 2021; PubMed: 33651975; DOI: 10.1016/j.neuron.2021.02.007

Experimental method

ELECTRON MICROSCOPY (3.1 Å)