7RHI

Cryo-EM structure of human rod CNGA1/B1 channel in cGMP-bound openII state

Summary for 7RHI

• Entry DOI: 10.2210/pdb7rhi/pdb
• EMDB information: 24458 24460 24461 24462 24463 24464 24465
• Descriptor: cGMP-gated cation channel alpha-1, Cyclic nucleotide-gated cation channel beta-1, CYCLIC GUANOSINE MONOPHOSPHATE (3 entities in total)
• Functional Keywords: ion channel, transport protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 286371.43

Authors

Xue, J.,Han, Y.,Jiang, Y. (deposition date: 2021-07-17, release date: 2021-11-03, Last modification date: 2022-01-19)

• Primary citation: Xue, J.,Han, Y.,Zeng, W.,Jiang, Y.; Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.; Neuron, 110:86-95.e5, 2022; PubMed: 34699778; DOI: 10.1016/j.neuron.2021.10.006

Experimental method

ELECTRON MICROSCOPY (3.31 Å)