7RHK
Cryo-EM structure of human rod CNGA1/B1 channel in L-cis-Diltiazem-trapped closed state
Summary for 7RHK
Entry DOI | 10.2210/pdb7rhk/pdb |
EMDB information | 24458 24460 24461 24462 24463 24464 24465 |
Descriptor | cGMP-gated cation channel alpha-1, Cyclic nucleotide-gated cation channel beta-1, CYCLIC GUANOSINE MONOPHOSPHATE, ... (4 entities in total) |
Functional Keywords | ion channel, transport protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 286785.94 |
Authors | |
Primary citation | Xue, J.,Han, Y.,Zeng, W.,Jiang, Y. Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel. Neuron, 110:86-95.e5, 2022 Cited by PubMed: 34699778DOI: 10.1016/j.neuron.2021.10.006 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.27 Å) |
Structure validation
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