3DLL
 
 | | The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning | | Descriptor: | 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Wilson, D.N, Schluenzen, F, Harms, J.M, Starosta, A.L, Connell, S.R, Fucini, P. | | Deposit date: | 2008-06-27 | | Release date: | 2008-09-16 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Proc.Natl.Acad.Sci.Usa, 105, 2008
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1Y69
 | | RRF domain I in complex with the 50S ribosomal subunit from Deinococcus radiodurans | | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L16, 50S ribosomal protein L27, ... | | Authors: | Wilson, D.N, Schluenzen, F, Harms, J.M, Yoshida, T, Ohkubo, T, Albrecht, R, Buerger, J, Kobayashi, Y, Fucini, P. | | Deposit date: | 2004-12-04 | | Release date: | 2005-03-01 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.33 Å) | | Cite: | X-ray crystallography on ribosome recycling: mechanism of binding and action of RRF on the 50S ribosomal subunit
EMBO J., 24, 2005
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6HTQ
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4V7E
 | | Model of the small subunit RNA based on a 5.5 A cryo-EM map of Triticum aestivum translating 80S ribosome | | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S10E, ... | | Authors: | Barrio-Garcia, C, Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R. | | Deposit date: | 2013-11-22 | | Release date: | 2014-07-09 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (5.5 Å) | | Cite: | Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion.
Nature, 506, 2014
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3J25
 | | Structural basis for TetM-mediated tetracycline resistance | | Descriptor: | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Tetracycline resistance protein tetM | | Authors: | Doenhoefer, A, Franckenberg, S, Wickles, S, Berninghausen, O, Beckmann, R, Wilson, D.N. | | Deposit date: | 2012-08-22 | | Release date: | 2012-10-17 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (7.2 Å) | | Cite: | Structural basis for TetM-mediated tetracycline resistance.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4V6I
 | | Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome | | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein RACK1 (RACK1), ... | | Authors: | Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R. | | Deposit date: | 2010-10-12 | | Release date: | 2014-07-09 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (8.8 Å) | | Cite: | Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107, 2010
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8S1U
 | | YlmH bound to stalled 50S subunits with RqcH and PtRNA | | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Paternoga, H, Wilson, D.N. | | Deposit date: | 2024-02-16 | | Release date: | 2024-06-12 | | Last modified: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | A role for the S4-domain containing protein YlmH in ribosome-associated quality control in Bacillus subtilis.
Nucleic Acids Res., 52, 2024
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8S1P
 | | YlmH bound to PtRNA-50S | | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | | Deposit date: | 2024-02-15 | | Release date: | 2024-06-12 | | Last modified: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (1.96 Å) | | Cite: | A role for the S4-domain containing protein YlmH in ribosome-associated quality control in Bacillus subtilis.
Nucleic Acids Res., 52, 2024
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6ENF
 | | Cryo-EM structure of a polyproline-stalled ribosome in the absence of EF-P | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Huter, P, Arenz, S, Wilson, D.N. | | Deposit date: | 2017-10-04 | | Release date: | 2017-11-22 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.
Mol. Cell, 68, 2017
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7P7R
 | | PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state I | | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | Authors: | Crowe-McAuliffe, C, Wilson, D.N. | | Deposit date: | 2021-07-20 | | Release date: | 2022-03-23 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Nat Commun, 13, 2022
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7NRD
 | | Structure of the yeast Gcn1 bound to a colliding stalled 80S ribosome with MBF1, A/P-tRNA and P/E-tRNA | | Descriptor: | 25S rRNA (3184-MER), 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | Authors: | Pochopien, A.A, Beckert, B, Wilson, D.N. | | Deposit date: | 2021-03-03 | | Release date: | 2021-04-14 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (4.36 Å) | | Cite: | Structure of Gcn1 bound to stalled and colliding 80S ribosomes.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NHN
 | | VgaL, an antibiotic resistance ABCF, in complex with 70S ribosome from Listeria monocytogenes | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Crowe-McAuliffe, C, Turnbull, K.J, Hauryliuk, V, Wilson, D.N. | | Deposit date: | 2021-02-10 | | Release date: | 2021-05-05 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Nat Commun, 12, 2021
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7NHM
 | | 70S ribosome from Staphylococcus aureus | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Crowe-McAuliffe, C, Murina, V, Hauryliuk, V, Wilson, D.N. | | Deposit date: | 2021-02-10 | | Release date: | 2021-05-05 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Nat Commun, 12, 2021
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7NRC
 | | Structure of the yeast Gcn1 bound to a leading stalled 80S ribosome with Rbg2, Gir2, A- and P-tRNA and eIF5A | | Descriptor: | 18S rRNA (1771-MER), 25S rRNA (3184-MER), 40S ribosomal protein S0-A, ... | | Authors: | Pochopien, A.A, Beckert, B, Wilson, D.N. | | Deposit date: | 2021-03-03 | | Release date: | 2021-05-05 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structure of Gcn1 bound to stalled and colliding 80S ribosomes.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NHK
 | | LsaA, an antibiotic resistance ABCF, in complex with 70S ribosome from Enterococcus faecalis | | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | Authors: | Crowe-McAuliffe, C, Kasari, M, Hauryliuk, V.H, Wilson, D.N. | | Deposit date: | 2021-02-10 | | Release date: | 2021-05-05 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Nat Commun, 12, 2021
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7NHL
 | | VgaA-LC, an antibiotic resistance ABCF, in complex with 70S ribosome from Staphylococcus aureus | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Crowe-McAuliffe, C, Murina, V, Hauryliuk, V, Wilson, D.N. | | Deposit date: | 2021-02-10 | | Release date: | 2021-05-05 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Nat Commun, 12, 2021
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7P7S
 | | PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state II | | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | Authors: | Crowe-McAuliffe, C, Wilson, D.N. | | Deposit date: | 2021-07-20 | | Release date: | 2022-02-23 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Nat Commun, 13, 2022
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7P7U
 | | E. faecalis 70S ribosome with P-tRNA, state IV | | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | Authors: | Crowe-McAuliffe, C, Wilson, D.N. | | Deposit date: | 2021-07-20 | | Release date: | 2022-02-23 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Nat Commun, 13, 2022
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7P7T
 | | PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state III | | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | Authors: | Crowe-McAuliffe, C, Wilson, D.N. | | Deposit date: | 2021-07-20 | | Release date: | 2022-02-23 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Nat Commun, 13, 2022
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7P7Q
 | | E. faecalis 70S ribosome bound by PoxtA-EQ2, high-resolution combined volume | | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | Authors: | Crowe-McAuliffe, C, Wilson, D.N. | | Deposit date: | 2021-07-20 | | Release date: | 2022-02-23 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Nat Commun, 13, 2022
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8B7Y
 | | Cryo-EM structure of the E.coli 70S ribosome in complex with the antibiotic Myxovalargin B. | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Koller, T.O, Graf, M, Wilson, D.N. | | Deposit date: | 2022-10-03 | | Release date: | 2023-01-25 | | Last modified: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition.
J.Am.Chem.Soc., 145, 2023
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4V6U
 | | Promiscuous behavior of proteins in archaeal ribosomes revealed by cryo-EM: implications for evolution of eukaryotic ribosomes | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10P, ... | | Authors: | Armache, J.-P, Anger, A.M, Marquez, V, Frankenberg, S, Froehlich, T, Villa, E, Berninghausen, O, Thomm, M, Arnold, G.J, Beckmann, R, Wilson, D.N. | | Deposit date: | 2012-08-09 | | Release date: | 2014-07-09 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Promiscuous behaviour of archaeal ribosomal proteins: Implications for eukaryotic ribosome evolution.
Nucleic Acids Res., 41, 2013
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4V6X
 | | Structure of the human 80S ribosome | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | Authors: | Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R. | | Deposit date: | 2013-02-27 | | Release date: | 2014-07-09 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (5 Å) | | Cite: | Structures of the human and Drosophila 80S ribosome.
Nature, 497, 2013
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4V5N
 | | tRNA translocation on the 70S ribosome: the post- translocational translocation intermediate TI(POST) | | Descriptor: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | | Authors: | Ratje, A.H, Loerke, J, Mikolajka, A, Bruenner, M, Hildebrand, P.W, Starosta, A.L, Doenhoefer, A, Connell, S.R, Fucini, P, Mielke, T, Whitford, P.C, Onuchic, J.N, Yu, Y, Sanbonmatsu, K.Y, Hartmann, R.K, Penczek, P.A, Wilson, D.N, Spahn, C.M.T. | | Deposit date: | 2010-10-21 | | Release date: | 2014-07-09 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (7.6 Å) | | Cite: | Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
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4V61
 | | Homology model for the Spinach chloroplast 30S subunit fitted to 9.4A cryo-EM map of the 70S chlororibosome. | | Descriptor: | 16S rRNA, 23S rRNA, 4.8S rRNA, ... | | Authors: | Sharma, M.R, Wilson, D.N, Datta, P.P, Barat, C, Schluenzen, F, Fucini, P, Agrawal, R.K. | | Deposit date: | 2007-11-09 | | Release date: | 2014-07-09 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (9.4 Å) | | Cite: | Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins
Proc.Natl.Acad.Sci.Usa, 104, 2007
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