1Y69 | | RRF DOMAIN I IN COMPLEX WITH THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS | | Descriptor: | 23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L16, ... | | Authors: | Wilson, D.N., Schluenzen, F., Harms, J.M., Yoshida, T., Ohkubo, T., Albrecht, R., Buerger, J., Kobayashi, Y., Fucini, P. | | Deposit date: | 2004-12-04 | | Release date: | 2005-03-01 | | Last modified: | 2017-08-02 | | Method: | X-RAY DIFFRACTION (3.33 Å) | | Cite: | X-ray crystallography on ribosome recycling: mechanism of binding and action of RRF on the 50S ribosomal subunit
EMBO J., 24, 2005
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3DLL | | THE OXAZOLIDINONE ANTIBIOTICS PERTURB THE RIBOSOMAL PEPTIDYL-TRANSFERASE CENTER AND EFFECT TRNA POSITIONING | | Descriptor: | rRNA-23S ribosomal RNA, rRNA-5S ribosomal RNA, 50S ribosomal protein L2, ... | | Authors: | Wilson, D.N., Schluenzen, F., Harms, J.M., Starosta, A.L., Connell, S.R., Fucini, P. | | Deposit date: | 2008-06-27 | | Release date: | 2008-09-16 | | Last modified: | 2015-07-22 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3IZD | | MODEL OF THE LARGE SUBUNIT RNA EXPANSION SEGMENT ES27L-OUT BASED ON A 6.1 A CRYO-EM MAP OF SACCHAROMYCES CEREVISIAE TRANSLATING 80S RIBOSOME. 3IZD IS A SMALL PART (AN EXPANSION SEGMENT) WHICH IS IN AN ALTERNATIVE CONFORMATION TO WHAT IS IN ALREADY 3IZF. | | Descriptor: | rRNA expansion segment ES27L in an "out" conformation | | Authors: | Armache, J.-P., Jarasch, A., Anger, A.M., Villa, E., Becker, T., Bhushan, S., Jossinet, F., Habeck, M., Dindar, G., Franckenberg, S., Marquez, V., Mielke, T., Thomm, M., Berninghausen, O., Beatrix, B., Soeding, J., Westhof, E., Wilson, D.N., Beckmann, R. | | Deposit date: | 2010-10-13 | | Release date: | 2010-12-01 | | Last modified: | 2012-05-30 | | Method: | ELECTRON MICROSCOPY (8.6 Å) | | Cite: | Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107, 2010
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4V6I | | LOCALIZATION OF THE SMALL SUBUNIT RIBOSOMAL PROTEINS INTO A 6.1 A CRYO-EM MAP OF SACCHAROMYCES CEREVISIAE TRANSLATING 80S RIBOSOME | | Descriptor: | 40S ribosomal protein RACK1 (RACK1), 40S ribosomal protein rpS0 (S2p), 40S ribosomal protein rpS3 (S3p), ... | | Authors: | Armache, J.-P., Jarasch, A., Anger, A.M., Villa, E., Becker, T., Bhushan, S., Jossinet, F., Habeck, M., Dindar, G., Franckenberg, S., Marquez, V., Mielke, T., Thomm, M., Berninghausen, O., Beatrix, B., Soeding, J., Westhof, E., Wilson, D.N., Beckmann, R. | | Deposit date: | 2010-10-12 | | Release date: | 2014-07-09 | | Last modified: | 2015-03-25 | | Method: | ELECTRON MICROSCOPY (8.8 Å) | | Cite: | Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107, 2010
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2D3O | | STRUCTURE OF RIBOSOME BINDING DOMAIN OF THE TRIGGER FACTOR ON THE 50S RIBOSOMAL SUBUNIT FROM D. RADIODURANS | | Descriptor: | 23S RIBOSOMAL RNA, 50S RIBOSOMAL PROTEIN L23, 50S RIBOSOMAL PROTEIN L24, ... | | Authors: | Schluenzen, F., Wilson, D.N., Hansen, H.A., Tian, P., Harms, J.M., McInnes, S.J., Albrecht, R., Buerger, J., Wilbanks, S.M., Fucini, P. | | Deposit date: | 2005-09-30 | | Release date: | 2005-12-06 | | Last modified: | 2018-10-03 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | The Binding Mode of the Trigger Factor on the Ribosome: Implications for Protein Folding and SRP Interaction
Structure, 13, 2005
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2E5L | | A SNAPSHOT OF THE 30S RIBOSOMAL SUBUNIT CAPTURING MRNA VIA THE SHINE- DALGARNO INTERACTION | | Descriptor: | 16S ribosomal RNA, 5'-R(*GP*AP*AP*AP*GP*A)-3', 30S ribosomal protein S2, ... | | Authors: | Kaminishi, T., Wilson, D.N., Takemoto, C., Harms, J.M., Kawazoe, M., Schluenzen, F., Hanawa-Suetsugu, K., Shirouzu, M., Fucini, P., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-12-21 | | Release date: | 2007-05-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine-Dalgarno interaction
Structure, 15, 2007
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2OM7 | | STRUCTURAL BASIS FOR INTERACTION OF THE RIBOSOME WITH THE SWITCH REGIONS OF GTP-BOUND ELONGATION FACTORS | | Descriptor: | Fragment of 16S rRNA (h14), Fragment of 16S rRNA (h15), Fragment of 16S rRNA (h44), ... | | Authors: | Connell, S.R., Wilson, D.N., Rost, M., Schueler, M., Giesebrecht, J., Dabrowski, M., Mielke, T., Fucini, P., Spahn, C.M.T. | | Deposit date: | 2007-01-21 | | Release date: | 2008-01-15 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (7.3 Å) | | Cite: | Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors.
Mol.Cell, 25, 2007
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2R1C | | COORDINATES OF THE THERMUS THERMOPHILUS RIBOSOME BINDING FACTOR A (RBFA) HOMOLOGY MODEL AS FITTED INTO THE CRYO-EM MAP OF A 30S-RBFA COMPLEX | | Descriptor: | Ribosome-binding factor A | | Authors: | Datta, P.P., Wilson, D.N., Kawazoe, M., Swami, N.K., Kaminishi, T., Sharma, M.R., Booth, T.M., Takemoto, C., Fucini, P., Yokoyama, S., Agrawal, R.K. | | Deposit date: | 2007-08-22 | | Release date: | 2008-03-18 | | Last modified: | 2011-07-13 | | Method: | ELECTRON MICROSCOPY (12.5 Å) | | Cite: | Structural aspects of RbfA action during small ribosomal subunit assembly.
Mol.Cell, 28, 2007
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2R1G | | COORDINATES OF THE THERMUS THERMOPHILUS 30S COMPONENTS NEIGHBORING RBFA AS OBTAINED BY FITTING INTO THE CRYO-EM MAP OF A 30S-RBFA COMPLEX | | Descriptor: | 16S RIBOSOMAL RNA HELIX 1, 16S RIBOSOMAL RNA HELIX 18, 16S RIBOSOMAL RNA HELIX 27, ... | | Authors: | Datta, P.P., Wilson, D.N., Kawazoe, M., Swami, N.K., Kaminishi, T., Sharma, M.R., Booth, T.M., Takemoto, C., Fucini, P., Yokoyama, S., Agrawal, R.K. | | Deposit date: | 2007-08-22 | | Release date: | 2008-03-18 | | Last modified: | 2011-07-13 | | Method: | ELECTRON MICROSCOPY (12.5 Å) | | Cite: | Structural aspects of RbfA action during small ribosomal subunit assembly.
Mol.Cell, 28, 2007
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2ZJP | | THIOPEPTIDE ANTIBIOTIC NOSIHEPTIDE BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF DEINOCOCCUS RADIODURANS | | Descriptor: | 50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, 50S RIBOSOMAL PROTEIN L35, ... | | Authors: | Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P. | | Deposit date: | 2008-03-07 | | Release date: | 2008-06-17 | | Last modified: | 2012-12-12 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30, 2008
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2ZJQ | | INTERACTION OF L7 WITH L11 INDUCED BY MICROCCOCIN BINDING TO THE DEINOCOCCUS RADIODURANS 50S SUBUNIT | | Descriptor: | ribosomal 23S RNA, ribosomal 5S RNA, 50S ribosomal protein L2, ... | | Authors: | Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P. | | Deposit date: | 2008-03-08 | | Release date: | 2008-06-17 | | Last modified: | 2014-04-16 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
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2ZJR | | REFINED NATIVE STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT (50S) FROM DEINOCOCCUS RADIODURANS | | Descriptor: | ribosomal 23S RNA, ribosomal 5S RNA, 50S ribosomal protein L2, ... | | Authors: | Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P. | | Deposit date: | 2008-03-08 | | Release date: | 2008-06-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
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3CF5 | | THIOPEPTIDE ANTIBIOTIC THIOSTREPTON BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF DEINOCOCCUS RADIODURANS | | Descriptor: | 50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, 50S RIBOSOMAL PROTEIN L35, ... | | Authors: | Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P. | | Deposit date: | 2008-03-02 | | Release date: | 2008-06-17 | | Last modified: | 2012-12-12 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30, 2008
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3DEG | | COMPLEX OF ELONGATING ESCHERICHIA COLI 70S RIBOSOME AND EF4(LEPA)-GMPPNP | | Descriptor: | A/L-tRNA, P-tRNA, 30S RNA helix 8, ... | | Authors: | Connell, S.R., Topf, M., Qin, Y., Wilson, D.N., Mielke, T., Fucini, P., Nierhaus, K.H., Spahn, C.M.T. | | Deposit date: | 2008-06-10 | | Release date: | 2008-08-19 | | Last modified: | 2014-04-16 | | Method: | ELECTRON MICROSCOPY (10.9 Å) | | Cite: | A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation
Nat.Struct.Mol.Biol., 15, 2008
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3J25 | | STRUCTURAL BASIS FOR TETM-MEDIATED TETRACYCLINE RESISTANCE | | Descriptor: | Tetracycline resistance protein tetM, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | Authors: | Doenhoefer, A., Franckenberg, S., Wickles, S., Berninghausen, O., Beckmann, R., Wilson, D.N. | | Deposit date: | 2012-08-22 | | Release date: | 2012-10-17 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (7.2 Å) | | Cite: | Structural basis for TetM-mediated tetracycline resistance.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3J5L | | STRUCTURE OF THE E. COLI 50S SUBUNIT WITH ERMBL NASCENT CHAIN | | Descriptor: | 50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, ... | | Authors: | Arenz, S., Ramu, H., Gupta, P., Berninghausen, O., Beckmann, R., Vazquez-Laslop, N., Mankin, A.S., Wilson, D.N. | | Deposit date: | 2013-10-23 | | Release date: | 2014-03-26 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide.
Nat Commun, 5, 2014
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3J7Z | | STRUCTURE OF THE E. COLI 50S SUBUNIT WITH ERMCL NASCENT CHAIN | | Descriptor: | 50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, ... | | Authors: | Arenz, S., Meydan, S., Starosta, A.L., Berninghausen, O., Beckmann, R., Vazquez-Laslop, N., Wilson, D.N. | | Deposit date: | 2014-08-27 | | Release date: | 2014-10-22 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Drug Sensing by the Ribosome Induces Translational Arrest via Active Site Perturbation.
Mol.Cell, 56, 2014
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3J9W | | CRYO-EM STRUCTURE OF THE BACILLUS SUBTILIS MIFM-STALLED RIBOSOME COMPLEX | | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein uS2, 30S ribosomal protein uS3, ... | | Authors: | Sohmen, D., Chiba, S., Shimokawa-Chiba, N., Innis, C.A., Berninghausen, O., Beckmann, R., Ito, K., Wilson, D.N. | | Deposit date: | 2015-03-16 | | Release date: | 2015-04-29 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structure of the Bacillus subtilis 70S ribosome reveals the basis for species-specific stalling.
Nat Commun, 6, 2015
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3J9Y | | CRYO-EM STRUCTURE OF TETRACYCLINE RESISTANCE PROTEIN TETM BOUND TO A TRANSLATING E.COLI RIBOSOME | | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S4, ... | | Authors: | Arenz, S., Nguyen, F., Beckmann, R., Wilson, D.N. | | Deposit date: | 2015-03-23 | | Release date: | 2015-04-15 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9- angstrom resolution.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4PSL | | CRYSTAL STRUCTURE OF PFUTHERMO-DBP-RP1 (CRYSTAL FORM I) | | Descriptor: | ssDNA binding protein, SULFATE ION | | Authors: | Gahlei, H., von Moeller, H., Eppers, D., Sohmen, D., Wilson, D.N., Loll, B., Wahl, M.C. | | Deposit date: | 2014-03-07 | | Release date: | 2014-04-30 | | Last modified: | 2014-06-25 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Entrapment of DNA in an intersubunit tunnel system of a single-stranded DNA-binding protein.
Nucleic Acids Res., 42, 2014
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4UE4 | | STRUCTURAL BASIS FOR TARGETING AND ELONGATION ARREST OF BACILLUS SIGNAL RECOGNITION PARTICLE | | Descriptor: | 6S RNA, FTSQ SIGNAL SEQUENCE, SIGNAL RECOGNITION PARTICLE PROTEIN | | Authors: | Beckert, B., Kedrov, A., Sohmen, D., Kempf, G., Wild, K., Sinning, I., Stahlberg, H., Wilson, D.N., Beckmann, R. | | Deposit date: | 2014-12-15 | | Release date: | 2015-09-09 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (7 Å) | | Cite: | Translational Arrest by a Prokaryotic Signal Recognition Particle is Mediated by RNA Interactions.
Nat.Struct.Mol.Biol., 22, 2015
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4UE5 | | STRUCTURAL BASIS FOR TARGETING AND ELONGATION ARREST OF BACILLUS SIGNAL RECOGNITION PARTICLE | | Descriptor: | 7S RNA, SRP14, SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68, ... | | Authors: | Beckert, B., Kedrov, A., Sohmen, D., Kempf, G., Wild, K., Sinning, I., Stahlberg, H., Wilson, D.N., Beckmann, R. | | Deposit date: | 2014-12-15 | | Release date: | 2015-09-09 | | Last modified: | 2018-10-24 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Translational Arrest by a Prokaryotic Signal Recognition Particle is Mediated by RNA Interactions.
Nat.Struct.Mol.Biol., 22, 2015
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4V5H | | E.COLI 70S RIBOSOME STALLED DURING TRANSLATION OF TNAC LEADER PEPTIDE. | | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Seidelt, B., Innis, C.A., Wilson, D.N., Gartmann, M., Armache, J., Villa, E., Trabuco, L.G., Becker, T., Mielke, T., Schulten, K., Steitz, T.A., Beckmann, R. | | Deposit date: | 2009-10-26 | | Release date: | 2014-07-09 | | Last modified: | 2018-04-18 | | Method: | ELECTRON MICROSCOPY (5.8 Å) | | Cite: | Structural insight into nascent polypeptide chain-mediated translational stalling.
Science, 326, 2009
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4V5M | | TRNA TRANLOCATION ON THE 70S RIBOSOME: THE PRE-TRANSLOCATIONAL TRANSLOCATION INTERMEDIATE TI(PRE) | | Descriptor: | 16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Ratje, A.H., Loerke, J., Mikolajka, A., Bruenner, M., Hildebrand, P.W., Starosta, A.L., Doenhoefer, A., Connell, S.R., Fucini, P., Mielke, T., Whitford, P.C., Onuchic, J.N., Yu, Y., Sanbonmatsu, K.Y., Hartmann, R.K., Penczek, P.A., Wilson, D.N., Spahn, C.M.T. | | Deposit date: | 2010-10-01 | | Release date: | 2014-07-09 | | Last modified: | 2017-08-02 | | Method: | ELECTRON MICROSCOPY (7.8 Å) | | Cite: | Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
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4V5N | | TRNA TRANSLOCATION ON THE 70S RIBOSOME: THE POST- TRANSLOCATIONAL TRANSLOCATION INTERMEDIATE TI(POST) | | Descriptor: | 16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Ratje, A.H., Loerke, J., Mikolajka, A., Bruenner, M., Hildebrand, P.W., Starosta, A.L., Doenhoefer, A., Connell, S.R., Fucini, P., Mielke, T., Whitford, P.C., Onuchic, J.N., Yu, Y., Sanbonmatsu, K.Y., Hartmann, R.K., Penczek, P.A., Wilson, D.N., Spahn, C.M.T. | | Deposit date: | 2010-10-21 | | Release date: | 2014-07-09 | | Last modified: | 2017-08-02 | | Method: | ELECTRON MICROSCOPY (7.6 Å) | | Cite: | Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
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