7NHL
VgaA-LC, an antibiotic resistance ABCF, in complex with 70S ribosome from Staphylococcus aureus
This is a non-PDB format compatible entry.
Summary for 7NHL
Entry DOI | 10.2210/pdb7nhl/pdb |
EMDB information | 12332 |
Descriptor | Lincosamide-streptogramin A resistance protein, 50S ribosomal protein L4, 50S ribosomal protein L5, ... (57 entities in total) |
Functional Keywords | antibiotic resistance element, abcf, antibiotic resistance, atpase, protein synthesis, ribosome |
Biological source | Staphylococcus haemolyticus More |
Total number of polymer chains | 53 |
Total formula weight | 2231635.24 |
Authors | Crowe-McAuliffe, C.,Murina, V.,Hauryliuk, V.,Wilson, D.N. (deposition date: 2021-02-10, release date: 2021-05-05, Last modification date: 2024-05-01) |
Primary citation | Crowe-McAuliffe, C.,Murina, V.,Turnbull, K.J.,Kasari, M.,Mohamad, M.,Polte, C.,Takada, H.,Vaitkevicius, K.,Johansson, J.,Ignatova, Z.,Atkinson, G.C.,O'Neill, A.J.,Hauryliuk, V.,Wilson, D.N. Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens. Nat Commun, 12:3577-3577, 2021 Cited by PubMed: 34117249DOI: 10.1038/s41467-021-23753-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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