7NHL
VgaA-LC, an antibiotic resistance ABCF, in complex with 70S ribosome from Staphylococcus aureus
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (0) | Lincosamide-streptogramin A resistance protein | polymer | 546 | 63265.3 | 1 | UniProt (A0SNL9) Pfam (PF00005) Pfam (PF12848) | Staphylococcus haemolyticus | |
| 2 | B (D) | P-tRNA fMet | polymer | 76 | 24506.6 | 1 | Staphylococcus aureus subsp. aureus NCTC 8325 | ||
| 3 | C (Z) | 50S ribosomal protein L27 | polymer | 94 | 10334.8 | 1 | UniProt (Q2FXT0) Pfam (PF01016) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 4 | D (P) | 50S ribosomal protein L16 | polymer | 144 | 16274.0 | 1 | UniProt (Q2FW13) Pfam (PF00252) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 5 | E (A) | 23S rRNA | polymer | 2923 | 946696.7 | 1 | GenBank (87201381) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 6 | F (a) | 16S rRNA | polymer | 1551 | 501711.2 | 1 | GenBank (CP000253.1) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 7 | G (B) | 5S rRNA | polymer | 115 | 36974.9 | 1 | GenBank (CP000253.1) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 8 | H (G) | 50S ribosomal protein L2 | polymer | 277 | 30217.2 | 1 | UniProt (P60430) Pfam (PF00181) Pfam (PF03947) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 9 | I (H) | 50S ribosomal protein L3 | polymer | 220 | 23760.3 | 1 | UniProt (Q2FW06) Pfam (PF00297) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 10 | J (I) | 50S ribosomal protein L4 | polymer | 207 | 22495.7 | 1 | UniProt (Q2FW07) Pfam (PF00573) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 11 | K (J) | 50S ribosomal protein L5 | polymer | 179 | 20296.6 | 1 | UniProt (Q2FW18) Pfam (PF00281) Pfam (PF00673) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 12 | L (K) | 50S ribosomal protein L6 | polymer | 178 | 19818.6 | 1 | UniProt (Q2FW21) Pfam (PF00347) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 13 | M (M) | 50S ribosomal protein L13 | polymer | 145 | 16359.4 | 1 | UniProt (Q2FW38) Pfam (PF00572) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 14 | N (N) | 50S ribosomal protein L14 | polymer | 122 | 13157.3 | 1 | UniProt (Q2FW16) Pfam (PF00238) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 15 | O (O) | 50S ribosomal protein L15 | polymer | 146 | 15628.9 | 1 | UniProt (P0A0F8) Pfam (PF00828) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 16 | P (Q) | 50S ribosomal protein L17 | polymer | 122 | 13771.8 | 1 | UniProt (Q2FW33) Pfam (PF01196) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 17 | Q (R) | 50S ribosomal protein L18 | polymer | 119 | 13124.1 | 1 | UniProt (Q2FW22) Pfam (PF00861) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 18 | R (S) | 50S ribosomal protein L19 | polymer | 116 | 13392.8 | 1 | UniProt (Q2FZ42) Pfam (PF01245) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 19 | S (T) | 50S ribosomal protein L20 | polymer | 118 | 13720.3 | 1 | UniProt (Q2FXQ1) Pfam (PF00453) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 20 | T (U) | 50S ribosomal protein L21 | polymer | 102 | 11354.1 | 1 | UniProt (Q2FXS8) Pfam (PF00829) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 21 | U (V) | 50S ribosomal protein L22 | polymer | 117 | 12857.9 | 1 | UniProt (Q2FW11) Pfam (PF00237) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 22 | V (W) | 50S ribosomal protein L23 | polymer | 91 | 10625.4 | 1 | UniProt (Q2FW08) Pfam (PF00276) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 23 | W (X) | 50S ribosomal protein L24 | polymer | 105 | 11561.5 | 1 | UniProt (Q2FW17) Pfam (PF00467) Pfam (PF17136) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 24 | X (Y) | 50S ribosomal protein L25 | polymer | 217 | 23810.6 | 1 | UniProt (Q2G0S0) Pfam (PF01386) Pfam (PF14693) | Staphylococcus aureus subsp. aureus NCTC 8325 | General stress protein CTC |
| 25 | Y (1) | 50S ribosomal protein L28 | polymer | 62 | 6995.3 | 1 | UniProt (Q2FZ60) Pfam (PF00830) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 26 | Z (2) | 50S ribosomal protein L29 | polymer | 69 | 8105.3 | 1 | UniProt (Q2FW14) Pfam (PF00831) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 27 | AA (3) | 50S ribosomal protein L30 | polymer | 59 | 6565.7 | 1 | UniProt (P0A0G2) Pfam (PF00327) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 28 | BA (6) | 50S ribosomal protein L33 2 | polymer | 49 | 5885.8 | 1 | UniProt (Q2FY22) Pfam (PF00471) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 29 | CA (8) | 50S ribosomal protein L35 | polymer | 66 | 7722.4 | 1 | UniProt (Q2FXQ0) Pfam (PF01632) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 30 | DA (7) | 50S ribosomal protein L34 | polymer | 45 | 5454.6 | 1 | UniProt (Q2FUQ0) Pfam (PF00468) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 31 | EA (d) | 30S ribosomal protein S3 | polymer | 217 | 24143.9 | 1 | UniProt (Q2FW12) Pfam (PF07650) Pfam (PF00189) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 32 | FA (e) | 30S ribosomal protein S4 | polymer | 200 | 23051.4 | 1 | UniProt (Q2FXK6) Pfam (PF00163) Pfam (PF01479) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 33 | GA (h) | 30S ribosomal protein S7 | polymer | 156 | 17826.6 | 1 | UniProt (P48940) Pfam (PF00177) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 34 | HA (k) | 30S ribosomal protein S10 | polymer | 102 | 11598.5 | 1 | UniProt (A0A0D1JTN2) Pfam (PF00338) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 35 | IA (l) | 30S ribosomal protein S11 | polymer | 129 | 13908.0 | 1 | UniProt (Q2FW31) Pfam (PF00411) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 36 | JA (o) | 30S ribosomal protein S14 type Z | polymer | 60 | 7246.7 | 1 | UniProt (Q2FW19) Pfam (PF00253) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 37 | KA (p) | 30S ribosomal protein S15 | polymer | 89 | 10634.3 | 1 | UniProt (Q2G2Q1) Pfam (PF00312) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 38 | LA (q) | 30S ribosomal protein S16 | polymer | 91 | 10253.9 | 1 | UniProt (Q2FZ45) Pfam (PF00886) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 39 | MA (u) | 30S ribosomal protein S20 | polymer | 83 | 9039.5 | 1 | UniProt (Q2FXY6) Pfam (PF01649) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 40 | NA (9) | 50S ribosomal protein L36 | polymer | 37 | 4318.4 | 1 | UniProt (Q2FW29) Pfam (PF00444) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 41 | OA (t) | 30S ribosomal protein S19 | polymer | 92 | 10639.3 | 1 | UniProt (Q2FW10) Pfam (PF00203) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 42 | PA (n) | 30S ribosomal protein S13 | polymer | 121 | 13747.9 | 1 | UniProt (Q2FW30) Pfam (PF00416) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 43 | QA (j) | 30S ribosomal protein S9 | polymer | 132 | 14857.0 | 1 | UniProt (Q2FW39) Pfam (PF00380) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 44 | RA (f) | 30S ribosomal protein S5 | polymer | 166 | 17770.5 | 1 | UniProt (Q2FW23) Pfam (PF00333) Pfam (PF03719) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 45 | SA (i) | 30S ribosomal protein S8 | polymer | 132 | 14854.3 | 1 | UniProt (Q2FW20) Pfam (PF00410) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 46 | TA (s) | 30S ribosomal protein S18 | polymer | 80 | 9332.0 | 1 | UniProt (Q2G111) Pfam (PF01084) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 47 | UA (g) | 30S ribosomal protein S6 | polymer | 98 | 11613.1 | 1 | UniProt (Q2G113) Pfam (PF01250) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 48 | VA (b) | RNA (5'-R(P*GP*GP*AP*GP*GP*UP*AP*UP*G)-3') | polymer | 15 | 4128.4 | 1 | Staphylococcus aureus subsp. aureus NCTC 8325 | ||
| 49 | WA (m) | 30S ribosomal protein S12 | polymer | 137 | 15320.9 | 1 | UniProt (P0A0H0) Pfam (PF00164) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 50 | XA (r) | 30S ribosomal protein S17 | polymer | 87 | 10196.9 | 1 | UniProt (Q2FW15) Pfam (PF00366) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 51 | YA (c) | 30S ribosomal protein S2 | polymer | 255 | 29136.4 | 1 | UniProt (Q2FZ25) Pfam (PF00318) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 52 | ZA (4) | 50S ribosomal protein L31 type B | polymer | 84 | 9737.9 | 1 | UniProt (Q2FWD8) Pfam (PF01197) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 53 | AB (5) | 50S ribosomal protein L32 | polymer | 57 | 6500.6 | 1 | UniProt (A0A0D1H2J5) Pfam (PF01783) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 54 | AC, AD, AE, AF, AG... (A, a, 0, G, O) | MAGNESIUM ION | non-polymer | 24.3 | 138 | Chemie (MG) | |||
| 55 | DB, EB (0) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 56 | BF, CC, DC, EE, FB... (A, P, a) | POTASSIUM ION | non-polymer | 39.1 | 18 | Chemie (K) | |||
| 57 | DH, EH, FH, GH (6, o, 9, 5) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
0: 1 - 522 (UniProt: A0SNL9)
| PDB | External Database | Details |
|---|---|---|
| Gln 105 | Glu 105 | engineered mutation |
| Gln 410 | Glu 410 | engineered mutation |
| Gly 523 | - | expression tag |
| Gly 524 | - | expression tag |
| Asp 525 | - | expression tag |
| Tyr 526 | - | expression tag |
| Lys 527 | - | expression tag |
| Asp 528 | - | expression tag |
| His 529 | - | expression tag |
| Asp 530 | - | expression tag |
| Gly 531 | - | expression tag |
| Asp 532 | - | expression tag |
| Tyr 533 | - | expression tag |
| Lys 534 | - | expression tag |
| Asp 535 | - | expression tag |
| His 536 | - | expression tag |
| Asp 537 | - | expression tag |
| Ile 538 | - | expression tag |
| Asp 539 | - | expression tag |
| Tyr 540 | - | expression tag |
| Lys 541 | - | expression tag |
| Asp 542 | - | expression tag |
| Asp 543 | - | expression tag |
| Asp 544 | - | expression tag |
| Asp 545 | - | expression tag |
| Lys 546 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 53 |
| Total formula weight | 2226301.4 | |
| Non-Polymers* | Number of molecules | 162 |
| Total formula weight | 5333.9 | |
| All* | Total formula weight | 2231635.2 |
