7NHK
LsaA, an antibiotic resistance ABCF, in complex with 70S ribosome from Enterococcus faecalis
This is a non-PDB format compatible entry.
Summary for 7NHK
Entry DOI | 10.2210/pdb7nhk/pdb |
EMDB information | 12331 |
Descriptor | ABC-F type ribosomal protection protein Lsa(A), 5S rRNA, 50S ribosomal protein L2, ... (58 entities in total) |
Functional Keywords | antibiotic resistance element, ribosomal protein, lsaa, abcf, target protection, antibiotic resistance, ribosome |
Biological source | Enterococcus faecalis More |
Total number of polymer chains | 53 |
Total formula weight | 2232137.36 |
Authors | Crowe-McAuliffe, C.,Kasari, M.,Hauryliuk, V.H.,Wilson, D.N. (deposition date: 2021-02-10, release date: 2021-05-05, Last modification date: 2021-06-23) |
Primary citation | Crowe-McAuliffe, C.,Murina, V.,Turnbull, K.J.,Kasari, M.,Mohamad, M.,Polte, C.,Takada, H.,Vaitkevicius, K.,Johansson, J.,Ignatova, Z.,Atkinson, G.C.,O'Neill, A.J.,Hauryliuk, V.,Wilson, D.N. Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens. Nat Commun, 12:3577-3577, 2021 Cited by PubMed: 34117249DOI: 10.1038/s41467-021-23753-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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