5MBV
| Cryo-EM structure of Lambda Phage protein GamS bound to RecBCD. | Descriptor: | Host-nuclease inhibitor protein gam, RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ... | Authors: | Wilkinson, M, Chaban, Y, Wigley, D.B. | Deposit date: | 2016-11-08 | Release date: | 2017-01-11 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones. Elife, 5, 2016
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8B1U
| RecBCD-DNA in complex with the phage protein Abc2 and host PpiB | Descriptor: | Anti-RecBCD protein 2, DNA (70-MER), MAGNESIUM ION, ... | Authors: | Wilkinson, M, Wilkinson, O.J, Feyerherm, C, Fletcher, E.E, Wigley, D.B, Dillingham, M.S. | Deposit date: | 2022-09-12 | Release date: | 2022-12-28 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub. Elife, 11, 2022
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8B1R
| RecBCD in complex with the phage protein gp5.9 | Descriptor: | MAGNESIUM ION, Probable RecBCD inhibitor gp5.9, RecBCD enzyme subunit RecB, ... | Authors: | Wilkinson, M, Wilkinson, O.J, Feyerherm, C, Fletcher, E.E, Wigley, D.B, Dillingham, M.S. | Deposit date: | 2022-09-12 | Release date: | 2022-12-28 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub. Elife, 11, 2022
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8B1T
| RecBCD-DNA in complex with the phage protein Abc2 | Descriptor: | Anti-RecBCD protein 2, DNA (70-MER), MAGNESIUM ION, ... | Authors: | Wilkinson, M, Wilkinson, O.J, Feyerherm, C, Fletcher, E.E, Wigley, D.B, Dillingham, M.S. | Deposit date: | 2022-09-12 | Release date: | 2022-12-28 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub. Elife, 11, 2022
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5LD2
| Cryo-EM structure of RecBCD+DNA complex revealing activated nuclease domain | Descriptor: | Fork-Hairpin DNA (70-MER), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Wilkinson, M, Chaban, Y, Wigley, D.B. | Deposit date: | 2016-06-23 | Release date: | 2016-10-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.83 Å) | Cite: | Mechanism for nuclease regulation in RecBCD. Elife, 5, 2016
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6QXT
| Cas1-Cas2-Csn2-DNA dimer complex from the Type II-A CRISPR-Cas system | Descriptor: | CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... | Authors: | Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. | Deposit date: | 2019-03-08 | Release date: | 2019-05-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (8.9 Å) | Cite: | Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System. Mol.Cell, 75, 2019
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6QY3
| Segment of the Cas1-Cas2-Csn2-DNA filament complex from the Type II-A CRISPR-Cas system | Descriptor: | CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... | Authors: | Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. | Deposit date: | 2019-03-08 | Release date: | 2019-05-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (9.1 Å) | Cite: | Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System. Mol.Cell, 75, 2019
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6QXF
| Cas1-Cas2-Csn2-DNA complex from the Type II-A CRISPR-Cas system | Descriptor: | CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... | Authors: | Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. | Deposit date: | 2019-03-07 | Release date: | 2019-05-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System. Mol.Cell, 75, 2019
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8A7P
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8A7Q
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8A7O
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8A7T
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8AWT
| IAPP S20G lag-phase fibril polymorph 2PF-P | Descriptor: | Islet amyloid polypeptide | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | Deposit date: | 2022-08-30 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural evolution of fibril polymorphs during amyloid assembly. Cell, 186, 2023
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8AZ3
| IAPP S20G growth-phase fibril polymorph 4PF-CU | Descriptor: | Islet amyloid polypeptide | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | Deposit date: | 2022-09-05 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural evolution of fibril polymorphs during amyloid assembly. Cell, 186, 2023
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8AZ4
| IAPP S20G plateau-phase fibril polymorph 2PF-L | Descriptor: | Islet amyloid polypeptide | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | Deposit date: | 2022-09-05 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Structural evolution of fibril polymorphs during amyloid assembly. Cell, 186, 2023
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8AZ5
| IAPP S20G plateau-phase fibril polymorph 4PF-CU | Descriptor: | Islet amyloid polypeptide | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | Deposit date: | 2022-09-05 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural evolution of fibril polymorphs during amyloid assembly. Cell, 186, 2023
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8AZ6
| IAPP S20G plateau-phase fibril polymorph 4PF-LU | Descriptor: | Islet amyloid polypeptide | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | Deposit date: | 2022-09-05 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural evolution of fibril polymorphs during amyloid assembly. Cell, 186, 2023
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8AZ7
| IAPP S20G plateau-phase fibril polymorph 4PF-LJ | Descriptor: | Islet amyloid polypeptide | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | Deposit date: | 2022-09-05 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural evolution of fibril polymorphs during amyloid assembly. Cell, 186, 2023
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8AZ0
| IAPP S20G growth-phase fibril polymorph 2PF-L | Descriptor: | Islet amyloid polypeptide | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | Deposit date: | 2022-09-05 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural evolution of fibril polymorphs during amyloid assembly. Cell, 186, 2023
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8AZ1
| IAPP S20G growth-phase fibril polymorph 2PF-C | Descriptor: | Islet amyloid polypeptide | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | Deposit date: | 2022-09-05 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural evolution of fibril polymorphs during amyloid assembly. Cell, 186, 2023
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8AZ2
| IAPP S20G growth-phase fibril polymorph 3PF-CU | Descriptor: | Islet amyloid polypeptide | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | Deposit date: | 2022-09-05 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural evolution of fibril polymorphs during amyloid assembly. Cell, 186, 2023
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8OHI
| Structure of the Fmoc-Tau-PAM4 Type 2 amyloid fibril | Descriptor: | Microtubule-associated protein tau | Authors: | Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J. | Deposit date: | 2023-03-21 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Local structural preferences in shaping tau amyloid polymorphism. Nat Commun, 15, 2024
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8OH2
| Structure of the Tau-PAM4 Type 1 amyloid fibril | Descriptor: | Microtubule-associated protein tau | Authors: | Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J. | Deposit date: | 2023-03-20 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Local structural preferences in shaping tau amyloid polymorphism. Nat Commun, 15, 2024
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8OHP
| Structure of the Fmoc-Tau-PAM4 Type 3 amyloid fibril | Descriptor: | Microtubule-associated protein tau | Authors: | Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J. | Deposit date: | 2023-03-21 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Local structural preferences in shaping tau amyloid polymorphism. Nat Commun, 15, 2024
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8OI0
| Structure of the Fmoc-Tau-PAM4 Type 4 amyloid fibril | Descriptor: | Microtubule-associated protein tau | Authors: | Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J. | Deposit date: | 2023-03-21 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Local structural preferences in shaping tau amyloid polymorphism. Nat Commun, 15, 2024
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