Author results

5X8Y
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A MUTATION IDENTIFIED IN NEONATAL MICROCEPHALY DESTABILIZES ZIKA VIRUS NS1 ASSEMBLY IN VITRO
Descriptor:ZIKV NS1
Authors:Wang, D., Chen, C., Liu, S., Zhou, H., Yang, K., Zhao, Q., Ji, X., Chen, C., Xie, W., Wang, Z., Mi, L.Z., Yang, H.
Deposit date:2017-03-03
Release date:2017-05-17
Method:X-RAY DIFFRACTION (2.817 Å)
Cite:A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in Vitro
Sci Rep, 7, 2017
1S9K
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CRYSTAL STRUCTURE OF HUMAN NFAT1 AND FOS-JUN ON THE IL-2 ARRE1 SITE
Descriptor:Human IL-2 ARRE1 Promoter Element, Plus Strand, Minus Strand, ...
Authors:Wang, D., Stroud, J.C., Chen, L.
Deposit date:2004-02-04
Release date:2005-06-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site
To be Published
1W24
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CRYSTAL STRUCTURE OF HUMAN VPS29
Descriptor:VACUOLAR PROTEIN SORTING PROTEIN 29
Authors:Wang, D., Guo, M., Teng, M., Niu, L.
Deposit date:2004-06-26
Release date:2005-03-23
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Human Vacuolar Protein Sorting Protein 29 Reveals a Phosphodiesterase/Nuclease-Like Fold and Two Protein-Protein Interaction Sites.
J.Biol.Chem., 280, 2005
2CGA
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BOVINE CHYMOTRYPSINOGEN A. X-RAY CRYSTAL STRUCTURE ANALYSIS AND REFINEMENT OF A NEW CRYSTAL FORM AT 1.8 ANGSTROMS RESOLUTION
Descriptor:CHYMOTRYPSINOGEN A
Authors:Wang, D., Bode, W., Huber, R.
Deposit date:1987-01-16
Release date:1987-04-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution.
J.Mol.Biol., 185, 1985
2E2H
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RNA POLYMERASE II ELONGATION COMPLEX AT 5 MM MG2+ WITH GTP
Descriptor:5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', ...
Authors:Wang, D., Bushnell, D.A., Westover, K.D., Kaplan, C.D., Kornberg, R.D.
Deposit date:2006-11-14
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2E2I
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RNA POLYMERASE II ELONGATION COMPLEX IN 5 MM MG+2 WITH 2'-DGTP
Descriptor:5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', ...
Authors:Wang, D., Bushnell, D.A., Westover, K.D., Kaplan, C.D., Kornberg, R.D.
Deposit date:2006-11-14
Release date:2006-12-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2E2J
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RNA POLYMERASE II ELONGATION COMPLEX IN 5 MM MG+2 WITH GMPCPP
Descriptor:5'-R(P*AP*UP*CP*GP*AP*GP*AP*GP*G)-3', 27-MER DNA template strand, 5'-D(P*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*A)-3', ...
Authors:Wang, D., Bushnell, D.A., Westover, K.D., Kaplan, C.D., Kornberg, R.D.
Deposit date:2006-11-14
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2NVQ
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RNA POLYMERASE II ELONGATION COMPLEX IN 150 MM MG+2 WITH 2'DUTP
Descriptor:5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', ...
Authors:Wang, D., Bushnell, D.A., Westover, K.D., Kaplan, C.D., Kornberg, R.D.
Deposit date:2006-11-13
Release date:2006-12-12
Last modified:2015-05-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2NVT
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RNA POLYMERASE II ELONGATION COMPLEX IN 150 MM MG+2 WITH GMPCPP
Descriptor:5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', 5'-D(P*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*TP*T)-3', 5'-D(*GP*TP*AP*CP*TP*TP*G)-3', ...
Authors:Wang, D., Bushnell, D.A., Westover, K.D., Kaplan, C.D., Kornberg, R.D.
Deposit date:2006-11-13
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.36 Å)
Cite:Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2NVX
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RNA POLYMERASE II ELONGATION COMPLEX IN 5 MM MG+2 WITH 2'-DUTP
Descriptor:5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 28-MER DNA template strand, ...
Authors:Wang, D., Bushnell, D.A., Westover, K.D., Kaplan, C.D., Kornberg, R.D.
Deposit date:2006-11-13
Release date:2006-12-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2NVY
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RNA POLYMERASE II FORM II IN 150 MM MN+2
Descriptor:DNA-directed RNA polymerase II largest subunit, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 45 kDa polypeptide, ...
Authors:Wang, D., Bushnell, D.A., Westover, K.D., Kaplan, C.D., Kornberg, R.D.
Deposit date:2006-11-13
Release date:2006-12-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2NVZ
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RNA POLYMERASE II ELONGATION COMPLEX WITH UTP, UPDATED 11/2006
Descriptor:5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', ...
Authors:Wang, D., Bushnell, D.A., Westover, K.D., Kaplan, C.D., Kornberg, R.D.
Deposit date:2006-11-14
Release date:2006-12-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2YU9
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RNA POLYMERASE II ELONGATION COMPLEX IN 150 MM MG+2 WITH UTP
Descriptor:5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', ...
Authors:Wang, D., Bushnell, D.A., Westover, K.D., Kaplan, C.D., Kornberg, R.D.
Deposit date:2007-04-06
Release date:2007-04-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
Cell(Cambridge,Mass.), 127, 2006
3GTG
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BACKTRACKED RNA POLYMERASE II COMPLEX WITH 12MER RNA
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, D., Bushnell, D.A., Huang, X., Westover, K.D., Levitt, M., Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.78 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTJ
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BACKTRACKED RNA POLYMERASE II COMPLEX WITH 13MER RNA
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, D., Bushnell, D.A., Huang, X., Westover, K.D., Levitt, M., Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTK
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BACKTRACKED RNA POLYMERASE II COMPLEX WITH 18MER RNA
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, D., Bushnell, D.A., Huang, X., Westover, K.D., Levitt, M., Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTL
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BACKTRACKED RNA POLYMERASE II COMPLEX WITH 13MER WITH G<>U MISMATCH
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, D., Bushnell, D.A., Huang, X., Westover, K.D., Levitt, M., Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.38 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTM
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CO-COMPLEX OF BACKTRACKED RNA POLYMERASE II WITH TFIIS
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, D., Bushnell, D.A., Huang, X., Westover, K.D., Levitt, M., Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTO
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BACKTRACKED RNA POLYMERASE II COMPLEX WITH 15MER RNA
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, D., Bushnell, D.A., Huang, X., Westover, K.D., Levitt, M., Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTP
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BACKTRACKED RNA POLYMERASE II COMPLEX WITH 24MER RNA
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, D., Bushnell, D.A., Huang, X., Westover, K.D., Levitt, M., Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTQ
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BACKTRACKED RNA POLYMERASE II COMPLEX INDUCED BY DAMAGE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, D., Bushnell, D.A., Huang, X., Westover, K.D., Levitt, M., Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3M3Y
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RNA POLYMERASE II ELONGATION COMPLEX C
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, D., Zhu, G., Huang, X., Lippard, S.J.
Deposit date:2010-03-10
Release date:2010-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M4O
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RNA POLYMERASE II ELONGATION COMPLEX B
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Wang, D., Zhu, G., Huang, X., Lippard, S.J.
Deposit date:2010-03-11
Release date:2010-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.57 Å)
Cite:X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.
Proc.Natl.Acad.Sci.USA, 107, 2010
4FF5
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STRUCTURE BASIS OF A NOVEL VIRULENCE FACTOR GHIP A GLYCOSYL HYDROLASE 25 OF STREPTOCOCCUS PNEUMONIAE PARTICIPATING IN HOST CELL INVASION
Descriptor:Glycosyl hydrolase 25, 1,2-ETHANEDIOL
Authors:Wang, D.
Deposit date:2012-05-31
Release date:2013-07-17
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structure basis for GhiA a surface associated Glycosyl hydrolase 25 of Streptococcus pneumoniae required for entry into eukaryotic cells and virulence
To be Published
4FFJ
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THE CRYSTAL STRUCTURE OF SPDHBPS FROM S.PNEUMONIAE
Descriptor:Riboflavin biosynthesis protein ribBA, SULFATE ION, GLYCEROL
Authors:Wang, D.
Deposit date:2012-06-01
Release date:2013-07-17
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The crystal structure of SpDHBPs from S. pneumoniae
To be Published